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| 1 | Randomized controlled trial of bipolar diathermy vs ultrasonic scalpel for closed hemorrhoidectomy显示文摘AIM:To compare hemorrhoidectomy with a bipolar electrothermal device or hemorrhoidectomy using an ultrasonically activated scalpel.METHODS:Sixty patients with grade Ⅲ or Ⅳ hemorrhoids were prospectively randomized to undergo closed hemorrhoidectomy assisted by bipolar diathermy(group 1) or hemorrhoidectomy with the ultrasonic scalpel(group 2).Operative data were recorded,and patients were followed at 1,3,and 6 wk to evaluate complications.Independent assessors were assigned to obtain postoperative pain scores,oral analgesic requirement and satisfaction scores.RESULTS:Reduced intraoperative blood loss median 0.9 mL(95% CI:0.8-3.7) vs 4.6 mL(95% CI:3.8-7.0),P = 0.001 and a short operating time median 16(95% CI:14.6-18.2) min vs 31(95% CI:28.1-35.3) min,P < 0.0001 was observed in group 1 compared with group 2.There was a trend towards lower postoperative pain scores on day 1 group 1 median 2(95% CI:1.8-3.5) vs group 2 median 3(95% CI:2.6-4.2),P = 0.135.Reduced oral analgesic requirement during postoperative 24 h after operation median 1(95% CI:0.4-0.9) tablet vs 1(95% CI:0.9-1.3) tablet,P = 0.006 was observed in group 1 compared with group 2.There was no difference between the two groups in the degree of patient satisfaction or number of postoperative complications.CONCLUSION:Bipolar diathermy hemorrhoidectomy is quick and bloodless and,although as painful as closed hemorrhoidectomy with the ultrasonic scalpel,is associated with a reduced analgesic requirement immediately after operation. | Akira Tsunoda Haruki Sada Takuya Sugimoto Nobuyasu Kano Mariko Kawana Tadanori Sasaki Hideki Hashimoto | 2011 | World Journal of Gastrointestinal Surgery2011，3，10： | 6 |
| 2 | Granular cell tumor of the common bile duct: A Japanese case显示文摘Granular cell tumor (GCT) of the biliary system is rare. It is reported that it occurs more commonly in young black women. We report here our seldom experience of a Japanese case in whom icterus was found as a first symptom just after a caesarean operation. A 36-year-old Japanese woman developed icterus after delivery by the Caesarean operation. A surgical operation was performed without can deny that there was a tumor-related change in a bile duct as a result of examination for various images. As a result of pathological evaluation, GCT was diagnosed. By the preoperative organization biomicroscopy result, it was not able to be attachd a right diagnosis. It was thought that this tumor, although rare, should be considered as one of the causes of biliary stenosis in the younger population. | Junko Saito Michiko Kitagawa Hiroshi Kusanagi Nobuyasu Kano Eiji Ishii So Nakaji Nobuto Hirata Kazuei Hoshi | 2012 | World Journal of Gastroenterology2012，18，43： | 2 |
| 3 | Differentiating a large abdominal cystic lymphangioma from multicystic mesothelioma: report of a case显示文摘 | Hiroshi Nagata Yutaka Yonemura Emel Canbay Haruaki Ishibashi Makoto Narita Makio Mike Nobuyasu Kano | 2014 | Surgery Today2014，，7： | 2 |
| 4 | 在有在有 diltiazem 的热门治疗以后的长期的肛门裂缝的病人的生活的质量显示文摘 AIM:To assess the physical and mental health of fissure patients before and after topical treatment with diltiazem.METHODS:Consecutive patients were enrolled prospectively into the study.Quality of life was measured with the short-forum 36 health survey(SF-36) before and after 6-wk treatment with diltiazem.Patients scored symptoms of pain,bleeding,and irritation using numeral rating scales at the initial and follow-up visits.Fissure healing was assessed and side effects were noted.RESULTS:Fissures healed in 21 of 30(70%) patients.There were significant reductions in the scores of pain,bleeding,and irritation after 1 wk of treatment,respectively.Four patients experienced perianal itching and one patient reported headache.When measured at baseline,pain and irritation showed a negative impact on two of the eight subscales on the SF-36,respectively(bodily pain and social functioning for pain;vitality and mental health for irritation).Repeating the SF-36 showed an improvement in bodily pain(P = 0.001).Patients whose fissures healed reported an improvement in bodily pain,health-perception,vitality,and mental health(P < 0.05).CONCLUSION:Successful treatment of chronic anal fissure with topical diltiazem leads to improvement in health-related quality of life. | Akira Tsunoda Yasuharu Kashiwagura Ken-ichi Hirose Tadanori Sasaki Nobuyasu Kano | 2012 | World Journal of Gastrointestinal Surgery2012，4，11： | 2 |
| 5 | Purification and Charac- terization of a Protease Degrading 30 ku Yolk Proteins ofthe Silkworm, Bomtryx mor/显示文摘 | NOBUYASU MAKI OKITSUGU YAMASHITA | 1997 | Insect Biochem Molecl1997，27，： | 1 |
| 6 | Comparison of low-level polycyclic aromatic hydrocarbons in sediment revealed by Soxhlet extraction, microwave-assisted extraction, and pressurized liquid extraction显示文摘 | Nobuyasu Itoh Masahiko Numata Yoshie Aoyagi Takashi Yarita | 2008 | Analytica Chimica Acta2008，，1： | 1 |
| 7 | Language Model Adaptation using Word Clustering显示文摘 | SHINSUKE M NISHIMURA M NOBUYASU I | 2003 | Joho Shori Gakkai Kenkyu Hokoku2003，2003，14： | 1 |
| 8 | Detection of food poisoning bacteria in fresh vegetables using DNA microar- ray显示文摘 | Masafumi I Nobuyasu Y Katsuji T | 2006 | Journal of Health Science2006，52，1： | 1 |
| 9 | Relapse of polyneuropathy,organomegaly,endocrinopathy,M-protein,and skin changes(POEMS) syndrome without increased level of vascular endothelial growth factor following successful autologous peripheral blood stem cell transplantation显示文摘 | Noboru I Jun T Nobuyasu Y | 2009 | Neuromuscul Disord2009，19，： | 1 |
| 10 | Effect of carbonsources on the growth and flavonoid formation of Scutellsria baicalensis stem callus cultures显示文摘 | Hisaka Y Nobuyasu C Kume W | 1986 | J Pharmacog1986，40，： | 1 |
| 11 | Optimization of aqueous acetylation for determination of hydroxy polycyclic aromat- ic hydrocarbons in water by stir bar sorptive extraction and thermal desorption - gas chromatography - mass spectrometry显示文摘 | Nobuyasu Itoh Hiroaki Tao Takashi Ibusuki | 2005 | Analyti- ca Chimica Acta2005，，535： | 1 |
| 12 | Quantitative analysis of the dependence of hardening on copper precipitate diameter and density in Fe-Cu alloys显示文摘 | KIMIHIRO N NOBUYASU N HIDEKI M | | 0，，： | 1 |
| 13 | Comparison of low-level polycyclic aromatic hydrocarbons in sediment revealed by Soxhlet extraction,microwave-assisted extraction,and pressurized liquid extraction显示文摘 | NOBUYASU I NUMATA M AOYAGI Y | 2008 | Analytica Chimica Acta2008，612，： | 1 |
| 14 | Isomerization reactions with sulfur-containing pentane over Metal/SO4^2- /ZrO2 catalysts显示文摘 | Katsuya Watanabe Nobuyasu Oshio Takahito Kawakami | 2004 | Applied Catalysis A : General2004，272，： | 1 |
| 15 | Progressive Disappearance of Anti-Hepatitis B Surface Antigen Antibody and Reverse Seroconversion after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Previous Hepatitis B Virus Infection显示文摘 | Masahiro Onozawa Satoshi Hashino Koh Izumiyama Kaoru Kahata Makoto Chuma Akio Mori Takeshi Kondo Nobuyasu Toyoshima Shuichi Ota Sumiko Kobayashi Shuhei Hige Tomomi Toubai Junji Tanaka Masahiro Imamura Masahiro Asaka | 2005 | Transplantation2005，，5： | 1 |
| 16 | Isomerization reactions with sulfur-containing pentane over Metal/SO4^2-/ZrO2 catalysts 显示文摘 | KATSUYA W NOBUYASU O TAKAHITO K | 2004 | Applied Catalysis A: General2004，272，12： | 1 |
| 17 | Effect of carbon sources on the growth and flavonoid formation of Scutellaria baicalensis stem callus cultures 显示文摘 | HISAKA Y NOBUYASU C KUME W | 1986 | J Pharmacog1986，40，1： | 1 |
| 18 | Comparison oflow-level polycyclic aromatic hydrocarbons in sediment revealed bySoxhlet extraction,microwave-assisted extraction,and pressurizedliquid extraction显示文摘 | Nobuyasu Itoh Masahiko Numata Yoshie Aoyagi | 2008 | Analytica Chimica Acta2008，62，1： | 1 |
| 19 | Detection of food poisoning bacteria in fresh vegetables using DNA microarray显示文摘 | Masafumi Ikeda Nobuyasu Yamaguchi Katsuji Tani | 2006 | Journal of Health Science2006，52，1： | 1 |
| 20 | Prognostic Value of the Sixth Edition AJCC/UICC TNM Classification for Differentiated Thyroid Carcinoma with Extrathyroid Extension显示文摘 | Nobuyuki Wada Hirotaka Nakayama Nobuyasu Suganuma Yoshihiko Masudo Yasushi Rino Munetaka Masuda Toshio Imada | 2007 | The Journal of Clinical Endocrinology & Metabolism2007，，1： | 1 |
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