|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ketamine anesthesia reduces intestinal ischemia/reperfusion injury in rats显示文摘AIM: To investigate the effects of ketamine anesthesia on the motility alterations and tissue injury caused by ischemia/reperfusion in rats. METHODS: Thirty male Wistar rats weighing 200-250 g were used. Ischemia was induced by ob-structing blood flow in 25% of the total small intesti-nal length (ileum) with a vascular clamp for 45 min, after which either 60 min or 24 h of reperfusion was allowed. Rats were either anesthetized with pento-barbital sodium (50 mg/kg) or ketamine (100 mg/kg). Control groups received sham surgery. After 60 min of reperfusion, the intestine was examined for mor-phological alterations, and after 24 h intestinal basic electrical rhythm (BER) frequency was calculated, and intestinal transit determined in all groups. RESULTS: The intestinal mucosa in rats that were anesthetized with ketamine showed moderate altera-tions such as epithelial lifting, while ulceration and hemorrhage was observed in rats that received pento-barbital sodium after 60 min of reperfusion. Quantita-tive analysis of structural damage using the Chiu scaleshowed significantly less injury in rats that received ketamine than in rats that did not (2.35 ± 1.14 vs 4.58 ± 0.50, P < 0.0001). The distance traveled by a mark-er, expressed as percentage of total intestinal length, in rats that received pentobarbital sodium was 20% ± 2% in comparison with 25.9% ± 1.64% in rats that re-ceived ketamine (P = 0.017). BER was not statistically different between groups. CONCLUSION: Our results show that ketamine anesthesia is associated with diminished intestinal injury and abolishes the intestinal transit delay induced by ischemia/reperfusion. | Carlos Rodrigo Cámara Francisco Javier Guzmán Ernesto Alexis Barrera Andrés Jesús Cabello Armando Garcia Nancy Esthela Fernández Eloy Caballero Jesus Ancer | 2008 | World Journal of Gastroenterology2008，14，33： | 5 |
| 2 | Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12显示文摘 | Birgit Oppmann Robin Lesley Bianca Blom Jackie C Timans Yuming Xu Brisdell Hunte Felix Vega Nancy Yu Jing Wang Komal Singh Francesca Zonin Elena Vaisberg Tatyana Churakova Man-ru Liu Daniel Gorman Janet Wagner Sandra Zurawski Yong-Jun Liu John S Abrams Ke | 2000 | Immunity2000，，5： | 2 |
| 3 | Global malaria mortality between 1980 and 2010: a systematic analysis显示文摘 | Christopher JL Murray Lisa C Rosenfeld Stephen S Lim Kathryn G Andrews Kyle J Foreman Diana Haring Nancy Fullman Mohsen Naghavi Rafael Lozano Alan D Lopez | 2012 | The Lancet2012，，9814： | 2 |
| 4 | Synthesis and processing of the trasmembrane envelope protein of equine infectious anemia virus显示文摘 | Nancy R Louise H Raymond C S | 1990 | J Virol1990，64，： | 1 |
| 5 | Global malaria mortality between 1980 and 2010: a systematic analysis显示文摘 | Christopher JL Murray Lisa C Rosenfeld Stephen S Lim Kathryn G Andrews Kyle J Foreman Diana Haring Nancy Fullman Mohsen Naghavi Rafael Lozano Alan D Lopez | 2012 | 2012 (9814)2012，，9814： | 1 |
| 6 | Con- version of Alanine, Asportate and Lactate to Glucose and CO in Liver from Stress-Susceptible and Stress-Resistant Pigs 显示文摘 | Peggy S Darrah Nancy M DiMarco Donald C Beitz | 1979 | Jour- nal of Nutrition1979，109，： | 1 |
| 7 | The untapped potential of genetically-engineered mouse models in chemoprevention research:Opportunities and challenges显示文摘 | CORY A S POWEL H B NANCY H C | 2008 | Cancer Prev Res2008，1，3： | 1 |
| 8 | New drugs for rheumatoid arthritis 显示文摘 | Nancy J Olsen C Michael S | 2004 | N Engl J Med2004，350，： | 1 |
| 9 | Genomic features of intertypic recombinant Sabin poliovirus strains excreted by primary vaccinees 显示文摘 | Nancy S C Sophie G Natalia R | 2001 | J Virol2001，75，13： | 1 |
| 10 | Nitrogen and phosphorus budgets for the Yucatdn littoral: an approach for groundwater management显示文摘 | NANCY A C FRANCISCO C JORGE H S | 2010 | Environmental Monitoring and Assessment2010，172，14： | 1 |
| 11 | Neonatal manipulation of oxytocin influences female reproductive behavior and success显示文摘 | Cushing B S Levine K Nancy L C | 2005 | Hormones and Behavior2005，47，1： | 1 |
| 12 | Polyamines and somatic embryngenesis in carrot Ⅲ effects of methylglyoxal bis (guanylhydrazone)显示文摘 | Subhash C Minnocha Nancy S | 1991 | Plant and Cell Physiol1991，32，3： | 1 |
| 13 | Controlling surface morphology of electrospun polystyrene fobers: Effect of humidity and molecular weight in the electro- spinning process显示文摘 | Cheryl L C Jean S S Nancy G T | 2004 | Macromolecules2004，37，2： | 1 |
| 14 | SAW parameters on Y-cut langasite structured materials显示文摘 | DEREK P DONALD M C NANCY S | 2007 | IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control2007，54，： | 1 |
| 15 | Polyamines and somatic embryogenesis in carrot Ⅲ effects of methylglyoxal bis(guanylhydrazone) 显示文摘 | Subhash C Minnocha Nancy S | 1991 | Plant and Cell Physiol1991，32，3： | 1 |
| 16 | Global malaria mortality between 1980 and 2010: a systematic analysis显示文摘 | Christopher JL Murray Lisa C Rosenfeld Stephen S Lim Kathryn G Andrews Kyle J Foreman Diana Haring Nancy Fullman Mohsen Naghavi Rafael Lozano Alan D Lopez | 2012 | The Lancet2012，，9814： | 1 |
| 17 | Validation of Companion Diagnostic for Detection of Mutations in Codons 12 and 13 of the KRAS Gene in Patients with Metastatic Colorectal Cancer: Analysis of the NCIC CTG CO.17 Trial显示文摘 | Harbison Christopher T Horak Christine E Ledeine Jean-Marie Mukhopadhyay Pralay Malone Daniel P O’Callaghan Chris Jonker Derek J Karapetis Christos S Khambata-Ford Shirin Gustafson Nancy Trifan Ovidiu C Chang Shao-Chun Ravetto Paul Green Geo | 2013 | Archives of Pathology & Laboratory Medicine2013，，6： | 1 |
| 18 | Topical Voriconazole as a Novel Treatment for Fungal Keratitis显示文摘 | William S Nancy C Demi D | 2006 | Antimicrob Agents Chemother2006，50，1： | 1 |
| 19 | Efficacy of reco mbinant methionyl human leptin therapy for the extreme insulin resistance of the rabson-mendenhallsy ndrome显示文摘 | Elaine C Janice R Y Nancy S | 2004 | J Clin Endocrinol Metab2004，89，4： | 1 |
| 20 | Reducing organic chloride contaminats in polyamide polyamines epichlorohydrin wet-strength resins显示文摘 | Danidl Nancy S C Stephen A F | 1991 | TAPPI1991，74，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员