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21篇 您的检索式:作者名="Nat R"
    题名 作者 年代 出处 被引量
1Relevance of MUC1 mucin variable number of tandem repeats polymorphism in H pylori adhesion to gastric epithelial cells显示文摘AIM:To evaluate the influence of MUC1 mucin variable number of tandem repeats (VNTR) variability on H pylori adhesion to gastric cells. METHODS: Enzyme linked immunosorbent assay (ELISA)-based adhesion assays were performed to measure the adhesion of different H pylori strains (HP26695 and HPTx30a) to gastric carcinoma cell lines (GP202 and MKN45) and GP202 clones expressing recombinant MUC1 with different VNTR lengths. RESULTS: Evaluation of adhesion results shows that H pylori pathogenic strain HP26695 has a significantly higher (P < 0.05) adhesion to all the cell lines and clones tested, when compared to the non-pathogenic strain HPTx30a. Bacteria showed a significantly higher (P < 0.05) adhesion to the GP202 cell line, when compared to the MKN45 cell line. Furthermore, both strains showed a significantly higher (P < 0.05) adhesion to GP202 clones with larger MUC1 VNTR domains. CONCLUSION: This work shows that MUC1 mucin variability conditions H pylori binding to gastric cells. The extent of bacterial adhesion depends on the size of theMUC1 VNTR domain. The adhesion is further dependent on bacterial pathogenicity and the gastric cell line. MUC1 mucin variability may contribute to determine H pylori colonization of the gastric mucosa.Natália R Costa Nuno Mendes Nuno T Marcos Celso A Reis Thomas Caffrey Michael A Hollingsworth Filipe Santos-Silva 2008World Journal of Gastroenterology2008,14,9:4
2Co-stimulatory and adhesion molecules of dendritic cells in rheumatoid arthritis显示文摘Banlanesu A Radu E Nat R 2002J Cell Mol Med2002,6,:1
3Salmonella carrier state in chicken: comparison of expression of immune response genes between susceptible and resistant animals显示文摘Jean-Rémy Sadeyen Jér?me Trotereau Philippe Velge José Marly Catherine Beaumont Paul A. Barrow Nat Bumstead Anne-Christine Lalmanach 2004Microbes and Infection2004,,14:1
4Transmission of h7n7 avian influenza a virus to human beings during a large outbreak in commercial poultry farms in the neth erlands 显示文摘Koopmans M Wilbrink B Conyn M Natrop G van der Nat H Vennema H Meijer A van Steenbergen J Fouchier R Osterhaus A Bosman A 2004Lancet2004,363,9409:1
5Co-stimulatory and adhesion molecules of dendritic cells in rheumatoid arthritis 显示文摘Balanescu A Radu E Nat R 2002J Cell Mol Med2002,6,3:1
6Wear in cast titanium carbide reinforced ferrous composites under dry sliding显示文摘Rai V K Srivastava R Nat h S K 1999Wear1999,231,2:1
7In-itu stresses in low-permeability,Nonmarine Rocks显示文摘Warpinski N R Teufel L W Sandia Nat SPE/DOE16400,1640,:1
8Early and late effect of infliximab on circulating dendritic cells phenotype in rheumatoid arthritis patients显示文摘Balanescu A Radu E Nat R etal 2005lnt J Clin Pharmacol Res2005,25,:1
9Jet pump cavitation 显示文摘CUNNINGHAM R G HANSEN A G NAT Y 1970ASME: Journal of Basic Engineer- ing1970,92,3:1
10Luminescence properties of Sm -aetivatedbarium chloroborates 显示文摘Qing Z Nat han K Mark R 2002Journal of Luminescence2002,104,12:1
11Microphysiological testing for chemosensitivity of living tumor ceils with multiparametric microsensor chips 显示文摘Otto A M Nat R Brischwein M 2003Cancer Detection and Prevention2003,27,4:1
12Neurogenic neuroepithelial and radial glial cells generated from six human embryonic stem cell lines in serum-free suspension and adherent cultures显示文摘Nat R Nilbratt M Narkilahti S 2007GGa2007,55,4:1
13Correlation between the immunophenotypical presentation of dendritic cells and the clinical response to anti-rheumatic treatment in rheumatoid arthritis 显示文摘Balanescu A Nat R Regalia T 2003Rom J Intern Med2003,41,3:1
14Neurogenic neuroepithelial and radial glial cells generated from six human embryonic stem cell lines in serum-free suspension and adherent cultures显示文摘Nat R Nilbratt M Narkilahti S 2007Glia2007,55,4:1
15Mechanisms of Nitrate Transfer from Soil to Stream in an Agricultural Watershed of French Brittany显示文摘Jér?me Molénat Patrick Durand Chantal Gascuel-Odoux Philippe Davy Gérard Gruau 2002Water Air and Soil Pollution (-)2002,,1:1
16Flow of a viscoelastic fluid over a stretching sheet 显示文摘RAJAGOPAL K R NAT Y GUPTA A S 1984Rheologica Acta1984,23,:1
17Use of high-performance liquid chromatography to study the pharmacokinetics of cnlistin sulfate in rats following intravenous administration显示文摘LI J MILNE R W NAT ION R L 2003Antimicrob Agents Chemoth- er2003,47,5:1
18Mechanisms of injury in bacterial meningitis 显示文摘Gerber J Nat R 2010Current Opinion in Neurology2010,23,3:1
19Correlation between the immunophenotypical presentation of dendritic cells and the clinical response to antirheumatic treatment in rheumatoid arthritis显示文摘Balanescu A Nat R Regalia T 2003Rom J Intern Med2003,41,3:1
20Value of the clinical examination in diagnosingenzootic pneumonia in fattening pigs 显示文摘NAT HUES H SPERGSER J ROSENGARTEN R 2012Vet J2012,193,2:1
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