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| 1 | 滋养细胞组织 GATA-3表达:445例免疫组化及其诊断应用分析显示文摘GATA-3主要表达在乳腺癌和尿路上皮癌,而在正常或病变滋养细胞组织中的表达报道甚少。作者选取445例正常/病变滋养细胞组织及其肿瘤进行 GATA-3免疫组化评估,根据着色强弱标记为(-~-),探讨GATA-3在下列组织中的表达意义。这些组织包括孕囊/中晚期妊娠胎盘/异位妊娠、葡萄胎、胎盘结节、正常/异常植入部位、绒毛膜癌、上皮样滋养细胞肿瘤、胎盘滋养细胞肿瘤、非典型平滑肌瘤(含平滑肌肉瘤)、子宫颈和肺的鳞状细胞癌。 | Natalie B Allen M G Ie-Ming S 许文静 余英豪 | 2015 | 临床与实验病理学杂志2015，31，9： | 11 |
| 2 | Foot length in fetuses with abnormal growth显示文摘 | NATALIE B M CANDE V A JOHN C M | 2000 | J Ultrasound Med2000，19，： | 1 |
| 3 | The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trial显示文摘 | Natalie C Ward Jason HY Wu Michael W Clarke Ian B Puddey Valerie Burke Kevin D Croft Jonathan M Hodgson | 2007 | Journal of Hypertension2007，，1： | 1 |
| 4 | Characterization of a legumain/vacuolar processing enzyme and YVADase activity in Papaver pollen显示文摘 | Maurice B Natalie S P Ruth M P | 2010 | Plant Mol Biol2010，74，： | 1 |
| 5 | Oxidative stress in human hypertension: association with antihypertensive treatment, gender, nutrition, and lifestyle显示文摘 | Natalie C Ward Jonathan M Hodgson Ian B Puddey Trevor A Mori Lawrence J Beilin Kevin D Croft | 2003 | Free Radical Biology and Medicine2003，，2： | 1 |
| 6 | Anterior-only Stabilization of Three-column Thoracolumbar Injuries显示文摘 | Rick C S Natalie M B Thomas M R | 2005 | J Spinal Disord Tech2005，18，1： | 1 |
| 7 | Electron microscopy ob- servation of human bocavirus (HBoV) in nasopharyngeal sam- pies from HBoV-infected children 显示文摘 | Natalie B Gay B Segondy M | 2007 | J Clin Microbiol2007，45，10： | 1 |
| 8 | Intra-arterial thrombolytics during endovascular thrombectomy for acute ischaemic stroke in the MR CLEAN Registry显示文摘Introduction The efficacy and safety of local intra-arterial(IA)thrombolytics during endovascular thrombectomy(EVT)for large-vessel occlusions is uncertain.We analysed how often IA thrombolytics were administered in the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands(MR CLEAN)Registry,whether it was associated with improved functional outcome and assessed technical and safety outcomes compared with EVT without IA thrombolytics.Methods In this observational study,we included patients undergoing EVT for an acute ischaemic stroke in the anterior circulation from the MR CLEAN Registry(March 2014-November 2017).The primary endpoint was favourable functional outcome,defined as an modified Rankin Scale score≤2 at 90 days.Secondary endpoints were reperfusion status,early neurological recovery and symptomatic intracranial haemorrhage(sICH).Subgroup analyses for IA thrombolytics as primary versus adjuvant revascularisation attempt were performed.Results Of the 2263 included patients,95(4.2%)received IA thrombolytics during EVT.The IA thrombolytics administered were urokinase(median dose,250000 IU(IQR,193750-250000))or alteplase(median dose,20 mg(IQR,12-20)).No association was found between IA thrombolytics and favourable functional outcome(adjusted OR(aOR),1.16;95%CI 0.71 to 1.90).Successful reperfusion was less often observed in those patients treated with IA thrombolytics(aOR,0.57;95%CI 0.36 to 0.90).The odds of sICH(aOR,0.82;95%CI 0.32 to 2.10)and early neurological recovery were comparable between patients treated with and without IA thrombolytics.For primary and adjuvant revascularisation attempts,IA thrombolytics were more often administered for proximal than for distal occlusions.Functional outcomes were comparable for patients receiving IA thrombolytics as a primary versus adjuvant revascularisation attempt.Conclusion Local IA thrombolytics were rarely used in the MR CLEAN Registry.In the relatively small study sample,no statistical difference was observed between groups in the rate of favourable functional outcome or sICH.Patients whom required and underwent IA thrombolytics were patients less likely to achieve successful reperfusion,probably due to selection bias. | Sabine L Collette Reinoud P H Bokkers Aryan Mazuri Geert J LycklamaàNijeholt Robert J van Oostenbrugge Natalie E LeCouffe Faysal Benali Charles B L M Majoie Jan Cees de Groot Gert Jan R Luijckx Maarten Uyttenboogaart 无 | 2023 | Stroke & Vascular Neurology2023，8，1： | 0 |
| 9 | Association between dairy intake,lipids and vascular structure and function in diabetes显示文摘AIM To determine lipid species that change in response to a change in dairy consumption. In addition, to investigate whether dairy associated lipid species are correlated with changes in measures of vascular structure and function.METHODS A 12-mo randomised controlled trial was conducted to determine the effect of increased consumption of fruit, vegetables and dairy, compared to usual diet, on measures of vascular structure and function in adults with type 1 and type 2 diabetes(n = 108). Thispaper comprises post-hoc analyses investigating the relationship between dairy intake, serum lipid species and vascular health. Central and peripheral blood pressure, carotid femoral pulse wave velocity, augmentation index, serum lipid species and dietary intake were measured at baseline and 3-mo. Common carotid artery intima media thickness was measured at baseline and 12-mo.RESULTS Serum lipid species [lysophosphatidylcholine(LPC) 14:0, LPC 15:0, LPC 16:1, phosphatidylcholine(PC) 29:0 PC 30:0, PC 31:0 and cholesterol ester(CE) 14:0] were associated with the change in full fat dairy consumption(rho 0.19-0.25; P < 0.05). The 3-mo change in some lipids was positively associated with the 3-mo change in central systolic [LPC 14:0(rho 0.30; P = 0.007), PC 30:0(rho 0.28; P = 0.010)] and diastolic blood pressure [LPC 14:0(rho 0.32; P = 0.004), LPC 15:0(rho 0.23; P = 0.04), LPC 16:1(rho 0.23; P = 0.035), PC 29:0(rho 0.28; P = 0.01), PC 30:0(rho 0.36; P = 0.001), PC 31:0(rho 0.30; P = 0.007)] and 12-mo change in common carotid artery intimal medial thickness [CE 14:0(rho 0.22; P = 0.02)]. Pulse wave velocity and augmentation index were unrelated to dairy and lipid species.CONCLUSION An increase in dairy associated lipids appears to be associated with an increase in blood pressure and common carotid intimal medial thickness. | Kristina S Petersen Jennifer B Keogh Natalie Lister Jacquelyn M Weir Peter J Meikle Peter M Clifton | 2017 | World Journal of Diabetes2017，8，5： | 0 |
| 10 | 父母2型糖尿病病史,转录因子7类似物2变异体和低胰岛素分泌与高血压发生相关显示文摘胰岛素分泌和高血压发生之间的关系尚未明确。研究人员假设,父母糖尿病史和转录因子7类似物2(transcription factor 7-like2,TCF7L2)rs7903146基因多态性与高血压发生相关。同时研究人员对另一个独立的队列进行分析,评估低胰岛素分泌与高血压发生的关系。 | Bonnet F Roussel R Natali A Cauchi S Petrie J Laville M Yengo L Froguel P Lange C Lantieri O Marre M Balkau B Ferrannini E 刘莉 叶鹏 | 2013 | 中华高血压杂志2013，21，9： | 0 |
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