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| 1 | Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs显示文摘AIM To investigate the long-term effect of dietary education on a low fermentable oligosaccharide, disaccharide and polyol(FODMAP) diet on irritable bowel syndrome(IBS) symptoms and quality of life(Qo L).METHODS Participants with IBS(Rome III) were randomized to two groups. Group I commenced a low FODMAP diet at baseline. At three months, group II, so far a comparator group, crossed over to a low FODMAP diet while group I started re-challenging foods. All patients completed the IBS SSS(IBS symptom severity scoring system, 0-500 points increasing with severity), IBS Qo L questionnaire(0-100 increasing with Qo L), a FODMAP specific food frequency questionnaire and provided a stool sample at baseline, three and six months for microbiome analysis.RESULTS Fifty participants were enrolled into group I(n = 23) or group II(n = 27). Participants in both groups were similar in baseline values but with more men in group I. There was a significantly lower IBS SSS(275.6 ± 63.6 to 128.8 ± 82.5 vs 246.8 ± 71.1 to 203.6 ± 70.1)(P < 0.0002) and increased Qo L(68.5 ± 18.0 to 83 ± 13.4 vs 72.9 ± 12.8 to 73.3 ± 14.4)(P < 0.0001) in group I vs group II at 3 mo. The reduced IBS SSS was sustained at 6 mo in group I(160 ± 102) and replicated in group II(124 ± 76). Fiber intake decreased on the low FODMAP diet(33 ± 17 g/d to 21 ± 8 g/d)(P < 0.01) and after re-introducing FODMAP containing foods increased again to 27 ± 9 g/d. There was no change seen in the intestinal microbiome when participants adopted a low FODMAP diet.CONCLUSION This study demonstrated that a reduction in FODMAPs improves symptoms in IBS and this improvement can be maintained while reintroducing FODMAPs. | Ruth M Harvie Alexandra W Chisholm Jordan E Bisanz Jeremy P Burton Peter Herbison Kim Schultz Michael Schultz | 2017 | World Journal of Gastroenterology2017，23，25： | 5 |
| 2 | Gas chromatography/snitIing port analysis and sensory evaluation of commercially dried bell peppers(Capsicum annuum) after rehydration显示文摘 | Van Ruth S M Roozen J P | 1994 | Food Chemistry1994，51，： | 1 |
| 3 | Regional energy demand responses to climate change methodology and application to the commonwealth of Massachusetts 显示文摘 | Amato A D Ruth M Kirshen P | 2005 | Climate Change2005，71，1： | 1 |
| 4 | In vitro binding of matrix metalloproteinase-2 (MMP-2), MMP-9,and bacterial collagenase on collagenous wound dressings 显示文摘 | Metzmacher I Ruth P Abel M | 2007 | Wound Repair Regen2007，15，4： | 1 |
| 5 | Enhancement and inhibition of microbial activity in hydrocarbon- contaminated arctic soils: implications for nutrient-amended bioremediation 显示文摘 | BRADDOCK J F RUTH M L CATTERALL P H | 1997 | Environ- mental Science & Technology1997，，31： | 1 |
| 6 | Estimation of a photon energy spectrum for a computed tomography scanner 显示文摘 | C Ruth P M Joseph | 1997 | Medical Physics1997，24，5： | 1 |
| 7 | Regional energy demand responses to climate change:methodology and application to the commonwealth of Massachusetts 显示文摘 | Amato A D Ruth M Kirshen P | 2005 | Climate Change2005，71，1： | 1 |
| 8 | Enhancement and inhibition of microbial activity in hydrocarbon- contaminated arctic soils: implications for nutrient-amended bioremediation 显示文摘 | BRADDOCK J F RUTH M L CATTERALL P H | 1997 | Environmental Science & Technology1997，，31： | 1 |
| 9 | Gas chromatography/sniffing port analysis and sensory evaluation of commercially dried bell pepper (capsicum annum) after rehydration显示文摘 | Van Ruth S M Roozen J P | 1994 | Food Chem1994，51，2： | 1 |
| 10 | Implica- tion of Loyalty Programs and Service Experiences for Customer Retention and Value显示文摘 | Ruth N Bohon P K Kannan M D Bramlett | | 0，，01： | 1 |
| 11 | Enhancement and inhibition of microbial activity in hydrocarbon-contaminated arctic soils: Implications for nutrient-amended bioremediation 显示文摘 | Braddock J F Ruth M L Catterall P H | 1997 | Environ Sci Technol1997，31，7： | 1 |
| 12 | Volatile compounds of rehydrated French beans bell peppers and leeks显示文摘 | Van Ruth S M Roozen J P | 1995 | Food Chem1995，53，1： | 1 |
| 13 | Terahertz Pulse Imaging in Reflection Geometry ofHuman Skin Cancer and Skin Tissue 显示文摘 | Woodward Ruth M Cole Bryan E Wallace Vincent P | 2002 | Physics inMedicine And Biology (S0031-9155)2002，47，21： | 1 |
| 14 | Modification of Polymers by Plasma-based Ion Implantation for Biomedical Applications 显示文摘 | McKenzie D R Newton M K Ruth P | 2004 | Surface & Coatings Technology2004，186，12： | 1 |
| 15 | 查看详情显示文摘 | Ruth P S A Barrett C A Kilner M A H | | 0，，： | 1 |
| 16 | Modification of the lipid-protein interaction in human low-density lipoprotein destabilizes and decreases oxidizabili- ty 显示文摘 | Peter M A Karl L Ruth P | 1999 | Biochemistry1999，38，2： | 1 |
| 17 | Effect of CVT-E002TM(COLD-fX(R)) versus a ginsenoside extract on systemic and gutassociated immune function显示文摘 | BIONDO P D GORUK S RUTH M R | 2008 | International Immunopharmacology2008，8，8： | 1 |
| 18 | Characterization of a legumain/vacuolar processing enzyme and YVADase activity in Papaver pollen显示文摘 | Maurice B Natalie S P Ruth M P | 2010 | Plant Mol Biol2010，74，： | 1 |
| 19 | Transferability of results of cost utility analyses for biologicals in inflammatory conditions for Central and Eastern European countries显示文摘 | László Gulácsi Fanni Rencz Márta Péntek Valentin Brodszky Ruth Lopert Noémi V. Hevér Petra Baji | 2014 | The European Journal of Health Economics2014，，1： | 1 |
| 20 | Gas chromatography/sniff- ing port analysis and sensory evaluation of commercially dried bell peppers ( Capsicum annuum) after rehydration 显示文摘 | van Ruth S M Roozen J P | 1994 | FoodChem1994，51，： | 1 |
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