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| 1 | Trabecular Bone Score: A Noninvasive Analytical Method Based Upon the DXA Image显示文摘 | Barbara C Silva William D Leslie Heinrich Resch Olivier Lamy Olga Lesnyak Neil Binkley Eugene V McCloskey John A Kanis John P Bilezikian | 2014 | J Bone Miner Res2014，，3： | 2 |
| 2 | CT angiography in acute ischemic stroke:preliminary results显示文摘 | Piero V Lawrence N T Neil M B | 2002 | Stroke2002，33，： | 1 |
| 3 | Indices of landscape pattern显示文摘 | Krummel J R | 1988 | Landscape Ecology1988，1，： | 1 |
| 4 | Novel therapeutic targetsin non - small cell lung cancer 显示文摘 | Alamgeer M Canju V Neil WD | 2013 | Curr Opin Pharmacol2013，，： | 1 |
| 5 | Graham, Indices of landscape pattern显示文摘 | O'Neil R V J R Krummel R H Gardner | 1988 | Landscape Ecology1988，1，： | 1 |
| 6 | Sustained Kilowatt Lasing in a Free-Electron Laser with Same-Cell Energy Recovery显示文摘 | Neil G R Bohn C L Benson S V | 2000 | PHYSICAL REVIEW LETTERS2000，84，4： | 1 |
| 7 | Expression patterns of slit and robo family members during vertebrate limb development显示文摘 | Neil V Victor L Izabell M | 2001 | Mechanisms of Development2001，106，： | 1 |
| 8 | Indices of land- scape structure 显示文摘 | O Neil R V Krummel J R Gardner R H | 1988 | Landscape Ecology1988，1，3： | 1 |
| 9 | Pancreaticogastrostomy following pancreaticoduodenectomy:Review of 102 cunsective cases显示文摘 | O`neil S Pickleman J Aranha G V | 2001 | World J Surg2001，25，5： | 1 |
| 10 | Shear strength properties of geomembrane/ geotextile interfaces显示文摘 | RUSSELL D JONES V NEIL Dixon | 1998 | Geotextiles and Geomembranes1998，16，： | 1 |
| 11 | The STAT3 oncogene as a predictive marker of drug resistance显示文摘 | Benjamin B Arnaud V Neil P | 2007 | Trend Mol Med2007，13，： | 1 |
| 12 | Comparative genonic hybridization for the diagnosis of melanoma显示文摘 | Christopher V Neil T | 2010 | Eur J Ptast Surg2010，33，12： | 1 |
| 13 | Pancreaticogastrostomy following ancreaticodupodenectomy:review of 102 consecutive cases显示文摘 | O Neil S Pickleman J Aranha G V | 2001 | World J Surg2001，25，5： | 1 |
| 14 | i ASPP oncoprotein is a key inhibitor of p53 conserved from worm to human显示文摘 | Bergamaschi D Samuels V O'Neil N J | 2003 | Nat Genet2003，33，2： | 1 |
| 15 | Replacing 100%fruit juice with whole fruit results in a trade-off of only two nutrients in the diets of children显示文摘 | T A Nicklas C E O'Neil V L Fulgoni | 2014 | Journal of the Academy of Nutrition and dietetics2014，114，9： | 1 |
| 16 | The value of the world's ecosystem service and nature capital 显示文摘 | O' Neil R V Rarelo J Raskin R G | 1998 | Ecological Economy1998，25，： | 1 |
| 17 | Prevalence of ischemic nephropathy in patients with renal insufficiency显示文摘 | O'Neil E A Hansen K J Canzanello V J | 1992 | Am Surg1992，58，： | 1 |
| 18 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 19 | A factor analysis of landscpe pattern and structure metrics显示文摘 | Riitters K H O Neil R V Hunsaker C T | 1995 | Landscape Ecology1995，10，： | 1 |
| 20 | Is it time to bury the ecosystem concept显示文摘 | O'Neil R V | 2001 | E-cology2001，82，12： | 1 |
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