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| 1 | NVP-BEZ235, a novel dual PI3K/mTOR inhibitor, enhances the radiosensitivity of human glioma stem cells in vitro显示文摘 | Wen-juan WANG Lin-mei LONG Neng YANG Qing-qing ZHANG Wen-jun JI Jiang-hu ZHAO Zheng-hong QIN ZhongWANG Gang CHEN Zhong-qin LIANG | 2013 | Acta Pharmacologica Sinica2013，34，5： | 14 |
| 2 | The Intervention Effect of Rosiglitozone in Ovarian Fibrosis of PCOS Rats显示文摘Objective To explore the Intervention effect of Rosiglitozone in ovarian fibrosis of PCOS rats.Methods 60 female SD rats were randomly divided into 3 groups:control group,model group and treatment group.The model and treatment groups were established by subcutaneous injection of DHEA,while the treatment group was given RGZ.The serum hormone values,pathohistology of ovarian structure of rats,ovarian ultrastructure and the expressions of TGF-β 1 and CTGF were detected.Results The PCOS model was established successfully.The expression intensity of TGF-β 1 and CTGF in Oocytes of the PCOS groups was 9.545±2.954 and 9.665±2.400,respectively and was significantly higher than that of the control group 6.636±2.264 and 7.036±2.133;after treatment with rosiglitazone,the expression was significantly decreased 6.980±2.421 and 6.642±2.721 as compared with that of the model group (P<0.05,P<0.001).The values in serum of the PCOS groups were 3.749±2.054 and 0.265±0.129,and 1.914±1.801 and 0.096±0.088 in the control group which had statistically significant difference (P<0.05,P<0.001).After treatment with rosiglitazone,the values were 2.3100±1.825 and 0.112±0.187 and were significantly different with those of the model group (P<0.05,P<0.001).Conclusion TGF-β 1 and CTGF play an important role in the development of ovary fibrosis in PCOS.However,RGZ may postpone the development of fibrosis by decreasing the levels of TGF-β 1 and CTGF. | MIAO Zhu Lin GUO Liang WANG Yong Xia CUI Rong YANG Ning HUANG Mi Qiong QIN Wei Bing CHEN Jin LI Hong Mei WANG Zi Neng WEI Xiang Cai | 2012 | Biomedical and Environmental Sciences2012，25，1： | 14 |
| 3 | Inhibition of cathepsin L sensitizes human glioma cells to ionizing radiation in vitro through NF-KB signaling pathway显示文摘 | Neng YANG Pan WANG Wen-juan WANG Yun-zhen SONG Zhong-qin LIANG | 2015 | Acta Pharmacologica Sinica2015，36，3： | 5 |
| 4 | A flow cytometer based protocol for quantitative analysis of bloom-forming cyanobacteria(Microcystis) in lake sediments显示文摘A quantitative protocol for the rapid analysis of Microcystis cells and colonies in lake sediment was developed using a modified flow cytometer,the CytoSense.For cell enumeration,diluted sediment samples containing Microcystis were processed with sonication to disintegrate colonies into single cells.An optimized procedure suggested that 5 mg dw(dry weight)/mL dilution combined with 200 W × 2 min sonication yielded the highest counting efficiency.Under the optimized determination conditions,the quantification limit of this protocol was 3.3×10 4 cells/g dw.For colony analysis,Microcystis were isolated from the sediment by filtration.Colony lengths measured by flow cytometry were similar to those measured by microscopy for the size range of one single cell to almost 400 μm in length.Moreover,the relationship between colony size and cell number was determined for three Microcystis species,including Microcystis flos-aquae,M.aeruginosa and M.wessenbergii.Regression formulas were used to calculate the cell numbers in differentsized colonies.The developed protocol was applied to field sediment samples from Lake Taihu.The results indicated the potential and applicability of flow cytometry as a tool for the rapid analysis of benthic Microcystis.This study provided a new capability for the high frequency monitoring of benthic overwintering and population dynamics of this bloom-forming cyanobacterium. | Quan Zhou Wei Chen Huiyong Zhang Liang Peng Liming Liu Zhiguo Han Neng Wan Lin Li Lirong Song | 2012 | Journal of Environmental Sciences2012，24，9： | 5 |
| 5 | Cathepsin L suppression increases the radiosensitivity of human glioma U251 cells via G2/M cell cycle arrest and DNA damage显示文摘 | Qing-qing ZHANG Wen-juan WANG Jun LI Neng YANG Gang CHEN Zhong WANG Zhong-qin LIANG | 2015 | Acta Pharmacologica Sinica2015，36，9： | 3 |
| 6 | In vitro porcine brain tubulin assembly inhibition by water extract from a Chinese medicinal herb,Tripterygium hypoglaucum Hutch显示文摘瞄准:在汇编和导管素的拆卸过程和它行动的可能的模式上调查 Tripterygium hypoglaucum 兔笼(THH ) 的效果。方法:在试管内猪的大脑导管素集会试金被采用在不同集中分析 THH 的禁止的效果(0.05 microg/L, 0.07 microg/L, 0.09 microg/L ) 。用番红花作原料而制成的植物盐基(0.0025 mmol/L, 0.0050 mmol/L, 0.0075 mmol/L ) 被用作积极控制。结果:THH 能显著地禁止根本测试的孤立的猪的大脑导管素的集会集中。结论:THH 能够经由导管素聚合抑制小径在哺乳动物导致非整倍性并且可以提出基因风险到人。 | Zi-Qin Liang Neng Cao Zhong-Kui Song Xu Wang | 2006 | World Journal of Gastroenterology2006，12，7： | 2 |
| 7 | Generation of strong magnetic fields with a laser-driven coil显示文摘As a promising new way to generate a controllable strong magnetic field, laser-driven magnetic coils have attracted interest in many research fields. In 2013, a kilotesla level magnetic field was achieved at the Gekko XⅡ laser facility with a capacitor–coil target. A similar approach has been adopted in a number of laboratories, with a variety of targets of different shapes. The peak strength of the magnetic field varies from a few tesla to kilotesla, with different spatiotemporal ranges. The differences are determined by the target geometry and the parameters of the incident laser. Here we present a review of the results of recent experimental studies of laser-driven magnetic field generation, as well as a discussion of the diagnostic techniques required for such rapidly changing magnetic fields. As an extension of the magnetic field generation, some applications are discussed. | Zhe Zhang Baojun Zhu Yutong Li Weiman Jiang Dawei Yuan Huigang Wei Guiyun Liang Feilu Wang Gang Zhao Jiayong Zhong Bo Han Neng Hua Baoqiang Zhu Jianqiang Zhu Chen Wang Zhiheng Fang Jie Zhang | 2018 | High Power Laser Science and Engineering2018，6，3： | 2 |
| 8 | Ground Response during Pile Driving显示文摘 | Jin-Hung Hwang Neng Liang Cheng-Hsing Chen | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001，，11： | 2 |
| 9 | Ground response during pile driving显示文摘 | Jin-Hung Hwang Neng Liang and Cheng-Hsing Chen | 2001 | Journal of Geotechnical and Geoenvironmental engineering2001，2001，： | 1 |
| 10 | Ground response during pile driving显示文摘 | in-Hung Hwang Neng Liang Cheng-Hsing Chen | 2001 | Journal of geotechnical and geoenvironmental engineering[J]2001，，： | 1 |
| 11 | Ground response during pile driving显示文摘 | HUANG Jin-hung NENG Liang CHEN Cheng-hsing | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001，127，11： | 1 |
| 12 | Theoretical prediction of the Kovat's retention index for oxygen-containing organic compounds using novel topological indices显示文摘 | Fengping Liu Yizeng Liang Chenzhong Cao Neng Zhou | 2007 | Analytica Chimica Acta2007，594，： | 1 |
| 13 | Implicit mental models in teaching cases: an empirical study of popular MBA cases in the United States and China显示文摘 | Neng Liang Jiaoqian Wang | 2004 | Academy of Management Learning&Education2004，3，4： | 1 |
| 14 | Ground response during pile driving显示文摘 | IN-HUNG HWANG NENG LIANG CHENG-HSING CHEN | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001，127，11： | 1 |
| 15 | Ground re- spense during pile driving 显示文摘 | Hwamg Jinhung Liang Neng Chen Cheng Sing | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001，127，11： | 1 |
| 16 | Ground response during pile driving显示文摘 | HWANGJ H LIANG Neng CHEN Cheng Hsing | 2001 | Journal of Geotechnical and Geoenironmental Engineering2001，127，11： | 1 |
| 17 | Fault diagnosis strategy for incompletely described samples and its application to refrigeration system显示文摘 | REN Neng LIANG Jun GU Bo | 2008 | Mechanical Systems and Signal Processing2008，22，2： | 1 |
| 18 | Mechanism study on the frequent variations of cell-bound microcystins in cy- anobacterial blooms in Lake Taihu: implications for water quality monitoring and assessments 显示文摘 | Chen Wei Peng Liang Wan Neng | 2009 | Chemosphere2009，77，11： | 1 |
| 19 | Ground response during pile driving 显示文摘 | HUANG Jin-hung LIANG Neng CHEN Cheng-hsing | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001，127，11： | 1 |
| 20 | 18β-Glycyrrhetinic acid interaction with bovine serum albumin显示文摘 | ZHOU Neng LIANG Yizeng WANG Ping | 2007 | Photochemistry-and Photobiology A: Chemistry2007，185，23： | 1 |
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