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| 1 | Anthropogenic influences on groundwater arsenic concentrations in Bangladesh 显示文摘 | Neumann R B Ashfaque K N Badruzzaman A B M | 2010 | Nature Geoscience2010,3,1: | 1 |
| 2 | Germline mutations in nonsyndromic pheochromocytoma显示文摘 | Neumann H P Bausch B McWhinney S R | 2002 | N Engl J Med2002,346,19: | 1 |
| 3 | Determination of the nucleotide sequence for the penton-base gene of human adenovirus type 5显示文摘 | Neumann R Chroboczek J Jacrot B | 1988 | Gene1988,69,1: | 1 |
| 4 | Metal-coded affinity tag labeling:a demonstration of analytical robustness and suitability for biological applications显示文摘 | AHRENDS R PIEPER S NEUMANN B | 2009 | Anal Chem2009,81,6: | 1 |
| 5 | Quantum register based on coupled electron spins in a room-temperature solid显示文摘 | Neumann P Kolesov R Naydenov B Beck J Rempp F Steiner M Jacques V Balasubramanian G Markham M L Twitchen D J Pezzagna S Meijer J Twamley J Jelezko F Wrachtrup J | 2010 | Nature Physics2010,,4: | 1 |
| 6 | Endotoxin-induced lung inflammation is independent of the complement membrane attack complex显示文摘 | Brauer R B Gegenfurtner C Neumann B | 2000 | Infect Immun2000,68,: | 1 |
| 7 | Reduction of nitroaromatic compounds by Fe(Ⅱ) species associated with iron- rich smectites 显示文摘 | Hofstetter T B Neumann A Schwarzenbach R P | 2006 | Environmental Science and Technology2006,40,1: | 1 |
| 8 | Dexmedeto- midine for awake fiberoptic intubation in a parturient with spinal muscular atrophy type for cesarean delivery 显示文摘 | Neumann M M Davio M B Macknet M R | 2009 | Int J Obstet Anesth2009,18,4: | 1 |
| 9 | The Oslo Rift:a review显示文摘 | Neumann E R Olsen K H Baldridge W S Sundvoll B | | 0,,: | 1 |
| 10 | Ionic conduction, rectification, and selectivity in single conical nanopores 显示文摘 | CERVERA J SCHIEDT B NEUMANN R | 2006 | The Journal of Chemical Physics2006,124,10: | 1 |
| 11 | Anthropogenic influences on groundwater arsenic concentrations in Bangladesh 显示文摘 | Neumann R B Ashfaque K N Badruzzaman A B | 2010 | Nature Geoscience2010,3,1: | 1 |
| 12 | Anthropogenic influences on groundwater arsenic concentrations in Bangladesh显示文摘 | Neumann R B Ashfaque K N Badruzzaman A B M | 2009 | Nature Geoscience2009,3,1: | 1 |
| 13 | White-coat hypertension and autonomic nervous system dysregulation显示文摘 | Neumann S A Jennings J R Muldoon M F Manuck S B | 2005 | Am J Hypertens2005,18,: | 1 |
| 14 | IRF-1 expression is essential for natural killer cells to suppress metastasis 显示文摘 | Ksienzyk A Neumann B Nandakumar R | 2011 | Cancer Res2011,71,: | 1 |
| 15 | On distance matrices and Laplacians 显示文摘 | Bapat R B Kirkland S J Neumann M | 2005 | Linear Algebra Appl2005,401,: | 1 |
| 16 | High rate of complete histopathological response in hepatocellular carcinoma patients after combined transarterial chemoembolization and stereotactic body radiation therapy显示文摘BACKGROUND Liver transplantation(LT)presents a curative treatment option in patients with early stage hepatocellular carcinoma(HCC)who are not eligible for resection or ablation therapy.Due to a risk of up 30%for waitlist drop-out upon tumor progression,bridging therapies are used to halt tumor growth.Transarterial chemoembolization(TACE)and less commonly stereotactic body radiation therapy(SBRT)or a combination of TACE and SBRT,are used as bridging therapies in LT.However,it remains unclear if one of those treatment options is superior.The analysis of explant livers after transplantation provides the unique opportunity to investigate treatment response by histopathology.AIM To analyze histopathological response to a combination of TACE and SBRT in HCC in comparison to TACE or SBRT alone.METHODS In this multicenter retrospective study,27 patients who received liver transplantation for HCC were analyzed.Patients received either TACE or SBRT alone,or a combination of TACE and SBRT as bridging therapy to liver transplantation.Liver explants of all patients who received at least one TACE and/or SBRT were analyzed for the presence of residual vital tumor tissue by histopathology to assess differences in treatment response to bridging therapies.Statistical analysis was performed using Fisher-Freeman-Halton exact test,Kruskal-Wallis and Mann-Whitney-U tests.RESULTS Fourteen patients received TACE only,four patients SBRT only,and nine patients a combination therapy of TACE and SBRT.There were no significant differences between groups regarding age,sex,etiology of underlying liver disease or number and size of tumor lesions.Strikingly,analysis of liver explants revealed that almost all patients in the TACE and SBRT combination group(8/9,89%)showed no residual vital tumor tissue by histopathology,whereas TACE or SBRT alone resulted in significantly lower rates of complete histopathological response(0/14,0%and 1/4,25%,respectively,P value<0.001).CONCLUSION Our data suggests that a combination of TACE and SBRT increases the rate of complete histopathological response compared to TACE or SBRT alone in bridging to liver transplantation. | Ulrike Bauer Sabine Gerum Falk Roeder Stefan Münch Stephanie E Combs Alexander B Philipp Enrico N De Toni Martha M Kirstein Arndt Vogel Carolin Mogler Bernhard Haller Jens Neumann Rickmer F Braren Marcus R Makowski Philipp Paprottka Markus Guba Fabian Geisler Roland M Schmid Andreas Umgelter Ursula Ehmer | 2021 | World Journal of Gastroenterology2021,27,24: | 1 |
| 17 | Movement direction or change in distance? Self-and object-related approach-avoidance motions 显示文摘 | Seibt B Neumann R Nussinson R | 2008 | Journal of Experimental Social Psychology2008,44,3: | 1 |
| 18 | Oral Ibuprofen versus Intravenous Ibuprofen or Intravenous Indomethacin for the Treatment of Patent Ductus Arteriosus in Preterm Infants:A Systematic Review and Meta-Analysis显示文摘 | Neumann R Schulzke SM Bührer C | | 0,,: | 1 |
| 19 | Prevalence, morphology and biology of renal cell carcinoma i in von Hippel-Lindau disease compared to sporadicrenal cell carcinoma 显示文摘 | Neumann H r Bender B U Berger D p | 1998 | J Urol1998,160,4: | 1 |
| 20 | Paclitaxel in combi-nation with sorafenib and bevacizumab in patients with locally advanced or metastatic solid tumors显示文摘 | Schultheis B Neumann H Roy R | | 0,,01: | 1 |