3篇
您的检索式：作者名="Nianlong LI"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | HER2 gene status and the relationship with p21 protein expression in gastric cancer显示文摘我们瞄准了到分析的目的有在胃的癌的 p21 蛋白质表示的 HER2 基因地位和它的关系。在 situ 杂交(鱼) 和 immunohistochemistry (IHC ) 的方法荧光技术被用来在胃的癌症的 59 种情况中检测 HER2 基因地位和 p53 蛋白质。HER2 基因扩大率的结果鱼察觉是 16.9%(10/59 ) ,在没有拷贝数字获得的 49 种情况中的 HER2 基因扩大和基因扩大是 49.2% 的一个总数(29/59 ) 。HER2 蛋白质表示是 42.4%(25/59 ) ,在有 +++ 的病人的 HER2 基因扩大率,, ++ HER2 蛋白质表示在有 + HER2 蛋白质表示的病人是 3/3 和 5/8,它是 2/14,有重要差别(P < 0.05 ) 。p21 蛋白质表示率是 49.2%(29/59 ) , HER2 基因扩大率和 p21 蛋白质表示在肿瘤侵略深度有重要差别,淋巴节点转移(P < 0.05 ) ;在组织学的类型的有的不统计的意义,变老,性差别(P > 0.05 ) 。结论 HER2 基因扩大率和基因拷贝数字断然与 p21 蛋白质表示, HER2 基因地位和联合察觉能提供的 p21 蛋白质的表示有关联在胃的癌症转移,病人条件开发和预后的引用值,它能也指导单个治疗的临床的开发。 | Yongjie Li Yangkun Wang Xianwei Zhang Fulin Li Nianlong Meng Xutao Yuan Jinsheng Song | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，3： | 3 |
| 2 | Protective effects and mechanisms of Lizhong decoction(理中汤) against non-alcoholic fatty liver disease in a rat model显示文摘OBJECTIVE: To investigate the protective effects and molecular mechanisms of Lizhong decoction( 理中汤, LZD) against non-alcoholic fatty liver disease(NAFLD). METHODS: Male Wistar rats were fed a high-fat diet for four weeks to induce NAFLD, and were administered LZD by gavage for four weeks. Potential therapeutic targets for NAFLD were analyzed using network pharmacology. Liver pathology was evaluated using Oil Red O and hematoxylin-eosin staining. Furthermore, mitochondrial function, lipid metabolism, oxidative stress, and inflammatory response were examined. RESULTS: Rats with NAFLD exhibited high levels of hepatic damage and cholesterol deposition. Moreover, apoptosis was increased, superoxide dismutase and glutathione content were reduced, malondialdehyde content was increased, and the protein expression of inflammatory cytokines and p-c-Jun N-terminal kinase was increased. The LZD treatment ameliorated mitochondrial dysfunction, reduced liver damage,inhibited oxidative stress and inflammatory response, upregulated peroxisome proliferator-activated receptor(PPAR)-γ expression, and suppressed dipeptidyl peptidase 4(DPP4) expression in the liver. CONCLUSION: It was found that LZD alleviates NAFLD by activating PPAR-γ and inhibiting DPP4. | YANG Jiayao TAO Dongqing MA Wei LIU Song LIAO Yan SHU Lei ZHANG Shu LI Chenyu DU Nianlong | 2022 | Journal of Traditional Chinese Medicine2022，42，5： | 0 |
| 3 | Sexual interference and allomaternal behavior as predictors of rank recognition in female golden snub-nosed monkeys显示文摘Rank recognition allows social animals to adapt to complex and changeable environments and to cope with hierarchical relationships within their societies(Crone 2017).Rank recognition can improve the distribution of advantageous resources,individual adaptation,and social cohesion among group-living animals(Marmolejo-Ramos and Angiulli 2014).Empirical evidence suggests that rank recognition is a basic behavioral manifestation of social cognition adopted by a wide range of insects,birds,and mammals,including nonhuman primates(Schmitt and Fischer 2011;Smith et al.2017).Unlike most other vertebrates,primates have unusually large brains and form complex social groups. | Haitao ZHAO Jiaxuan LI Yan WANG Nianlong LI Xiaowei WANG Chengliang WANG Yi REN Ting JIA Wei LI Ruliang PAN Baoguo LI | 2021 | Current Zoology2021，67，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员