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| 1 | 与蝉花有关的虫草菌生物多样性的研究Ⅱ:重要药用真菌蝉花有性型的发现及命名显示文摘我国重要药用真菌蝉花的分类地位和学名在国内外长期混乱,因其有性型未被发现,长期以来误作为根据巴西标本命名的Isaria (Paecilomyces) cicadae。作者最近在井冈山发现了其有性型,研究了标本及分离物的形态特征及多位点系统发育特征,并与GenBank中相关种类的序列进行了对比,证明I.cicadae是物种复合群,确定蝉花是虫草科虫草属中的新种,使用传统药用真菌蝉花的古老名称将其命名为Cordycepschanhua。蝉花子座淡橙色到淡桔黄色,子囊壳半埋生,475–602×222–319μm,子囊孢子246–360×1.5–1.8μm,分孢子圆筒形,6.4–13.8×2.1–3.1μm。孢梗束淡黄色至淡黄褐色,分生孢子长椭圆形或圆筒形,3.5–10.5×1.5–4.5μm。 | 李增智 栾丰刚 HYWEL-JONES Nigel L 张胜利 陈名君 黄勃 孙长胜 陈祝安 李春如 谭悠久 董建飞 | 2021 | 菌物学报2021，40，1： | 18 |
| 2 | Subcellular spatial resolution achieved for deep-brain imaging in vivo using a minimally invasive multimode fiber显示文摘Achieving intravital optical imaging with diffraction-limited spatial resolution of deep-brain structures represents an important step toward the goal of understanding the mammalian central nervous system1–4.Advances in wavefrontshaping methods and computational power have recently allowed for a novel approach to high-resolution imaging,utilizing deterministic light propagation through optically complex media and,of particular importance for this work,multimode optical fibers(MMFs)5–7.We report a compact and highly optimized approach for minimally invasive in vivo brain imaging applications.The volume of tissue lesion was reduced by more than 100-fold,while preserving diffraction-limited imaging performance utilizing wavefront control of light propagation through a single 50-μm-core MMF.Here,we demonstrated high-resolution fluorescence imaging of subcellular neuronal structures,dendrites and synaptic specializations,in deep-brain regions of living mice,as well as monitored stimulus-driven functional Ca2+responses.These results represent a major breakthrough in the compromise between high-resolution imaging and tissue damage,heralding new possibilities for deep-brain imaging in vivo. | Sebastian A.Vasquez-Lopez Raphaël Turcotte Vadim Koren Martin Plöschner Zahid Padamsey Martin J.Booth TomášČižmár Nigel J.Emptage | 2018 | Light(Science & Applications)2018，7，1： | 4 |
| 3 | 策略将在肝移植以后减少丙肝病毒复发显示文摘 Hepatitis C virus (HCV) is a major health problem that leads to chronic hepatitis, cirrhosis and hepatocellular carcinoma, being the most frequent indication for liver transplantation in several countries. Unfortunately, HCV re-infects the liver graft almost invariably following reperfusion, with an accelerated history of recurrence, leading to 10%-30% of patients progressing to cirrhosis within 5 years of transplantation. In this sense, some groups have even advocated for not retransplanting this patients, as lower patient and graftoutcomes have been reported. However, the management of HCV recurrence is being optimized and several strategies to reduce post-transplant recurrence could improve outcomes, decrease the rate of re-transplantation and optimize the use of available grafts. Three moments may be the focus of potential actions in order to decrease the impact of viral recurrence: the pretransplant moment, the transplant environment and the post-transplant management. In the pre-transplant setting, it is not well established if reducing the pre transplant viral load affects the risk for HCV progression after transplant. Obviously, antiviral treatment can render the patient HCV RNA negative post transplant but the long-term benefit has not yet been fully established to justify the cost and clinical risk. In the transplant moment, factors as donor age, cold ischemia time, graft steatosis and ischemia/reperfusion injury may lead to a higher and more aggressive viral recurrence. After the transplant, discussion about immunosuppression and the moment to start the treatment (prophylactic, pre-emptive or once-confirmed) together with new antiviral drugs are of interest. This review aims to help clinicians have a global overview of posttransplant HCV recurrence and strategies to reduce its impact on our patients. | Ruben Ciria María Pleguezuelo Shirin Elizabeth Khorsandi Diego Davila Abid Suddle Hector Vilca-Melendez Sebastian Rufian Manuel de la Mata Javier Briceo Pedro López Cillero Nigel Heaton | 2013 | World Journal of Hepatology2013，5，5： | 2 |
| 4 | Disruption of the acetate kinase (ack) gene of Clostridium acetobutylicum results in delayed acetate production显示文摘 | Wouter Kuit Nigel Minton Ana López-Contreras Gerrit Eggink | 2012 | Applied Microbiology and Biotechnology2012，，3： | 1 |
| 5 | Intrapulmonary lesions: percutaneous automa ted biopsy with a detachable, 18-gauge,coaxial cutting needle显示文摘 | Oliver L Nigel H | 1998 | Radiology1998，207，10： | 1 |
| 6 | A ferricchelatereductase for iron uptake from soils显示文摘 | Nigel J R Catherine M P Connolly E L | 1999 | Nature1999，397，69： | 1 |
| 7 | Phylogenetic classification of Cordyceps and the clavicipitaceous fungi显示文摘 | Sung G H Nigel L Hywel-Jones N L Sung J M Luangsa-Ard J J Shrestha B Spatafora J W | 2007 | Studies in Mycology2007，57，： | 1 |
| 8 | RULA: a survey method for the investigation of work-related upper limb disorders 显示文摘 | McAtamney L Nigel Corlett E | 1993 | Appl Ergon1993，24，2： | 1 |
| 9 | Protease-activated receptors in inflammation, neuronal signaling and pain显示文摘 | Nathalie Vergnolle John L Wallace Nigel W Bunnett Morley D Hollenberg | 2001 | Trends in Pharmacological Sciences2001，，3： | 1 |
| 10 | Function and transcript analysis of gibberellin-biosynthetic enzymes in wheat显示文摘 | Nigel A Daniel E John L | 2006 | Planta2006，223，3： | 1 |
| 11 | Nanocry stalline semiconductors synthesis properties and perspectives显示文摘 | Paul O Nigel L P | 2001 | ChemMater2001，13，： | 1 |
| 12 | 显示文摘 | John L Dektar Nigel P Hacker | 1990 | J Am Chem Soc1990，112，： | 1 |
| 13 | Pharmacological characterization of strychnine and brucine analogues at glycine and α7 nicotinic acetylcholine receptors显示文摘 | Anders AJ Parviz G Nigel J M et a l | 2006 | European Journal of Pharamacology2006，539，： | 1 |
| 14 | Phylogenetic classification of Cordyceps and the clavicipitaceous fungi显示文摘 | Sung Gi-Ho Nigel L Hywel-Jones Sung Jae-Mo Jennifer Luangsa-ard J Bhushan Shrestha Joseph W Spatafora | 2007 | Studies in Mycology2007，57，： | 1 |
| 15 | Disruption of the acetate kinase(ack)gene of Clostridium acetobutylicum results in delayed acetate production显示文摘 | Wouter K Nigel P M Ana M L | 2012 | Applied and Microbiology Biotechnology2012，3，94： | 1 |
| 16 | Identifying managerial influences on exporting: Past research and future directions显示文摘 | eonidou L Katsikeas C Constantine S and Piercy Nigel F | 1998 | Journal of International Marketing1998，6，2： | 1 |
| 17 | Effects of treatment with myo-inositol or its 1,2,6-triphodphate (PP56) on nerve conduction instreptozocin-diabetes显示文摘 | A L Carrington Nigel A Calcutt Claudia B Ettlinger | 1993 | Eur J of Pharmacology1993，237，： | 1 |
| 18 | A TaqMan real-time PCR system for the identification and quantification of bovine DNA in meats, milks and cheeses显示文摘 | Zhang C L Mark R F Nigel W S | 2007 | Food Control2007，18，9： | 1 |
| 19 | , 2000, Bioadsorption of pentachlorophenol fromaqueous solution by activated sludge biomass显示文摘 | Qian Y Nigel H | 2000 | Bioresource Technology2000，75，： | 1 |
| 20 | Nanocrystalline semiconductors:synthesis, properties and perspectives显示文摘 | Tito T D Paul O B Nigel L P | 2001 | Chem Mater2001，13，1： | 1 |
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