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| 1 | Clinical implications of diabetes in chronic liver disease:Diagnosis,outcomes and management,current and future perspectives显示文摘Diabetes mellitus(DM)is common in liver cirrhosis(LC).The pathophysiological association is bidirectional.DM is a risk factor of LC and LC is a diabetogenic condition.In the recent years,research on different aspects of the association DM and LC has been intensified.Nevertheless,it has been insufficient and still exist many gaps.The aims of this review are:(1)To discuss the latest understandings of the association of DM and LC in order to identify the strategies of early diagnosis;(2)To evaluate the impact of DM on outcomes of LC patients;and(3)To select the most adequate management benefiting the two conditions.Literature searches were conducted using Pub Med,Ovid and Scopus engines for DM and LC,diagnosis,outcomes and management.The authors also provided insight from their own published experience.Based on the published studies,two types of DM associated with LC have emerged:Type 2 DM(T2 DM)and hepatogenous diabetes(HD).High-quality evidences have determined that T2 DM or HD significantly increase complications and death pre and post-liver transplantation.HD has been poorly studied and has not been recognized as a complication of LC.The management of DM in LC patients continues to be difficult and should be based on drug pharmacokinetics and the degree of liver failure.In conclusion,the clinical impact of DM in outcomes of LC patients has been the most studied item recently.Nevertheless many gaps still exist particularly in the management.These most important gaps were highlighted in order to propose future lines for research. | Diego García-Compeán Emanuela Orsi Ramesh Kumar Felix Gundling Tsutomu Nishida Jesús Zacarías Villarreal-Pérez Ángel N Del Cueto-Aguilera JoséA González-González Giuseppe Pugliese | 2022 | World Journal of Gastroenterology2022，28，8： | 4 |
| 2 | PNAS:糖尿病药物的免疫抗癌作用显示文摘二甲双胍是一类双胍类口服降血糖药,特别适合于用单纯饮食控制及体育锻炼治疗无效的II型糖尿病,也就是肥胖II型糖尿病。近年来的研究表明二甲双胍与某些抗癌特性有关联,回访调查也表明这种广泛应用的糖尿病药物可以使某些癌症患者受益。 | Eikawa S Nishida M Mizukami S | 2015 | 疾病监测2015，30，1： | 2 |
| 3 | Cementite decomposition in heavily drawn pearlite steel wire显示文摘 | K Hono M Ohnuma M Murayama S Nishida A Yoshie T Takahashi | 2001 | Scripta Materialia2001，，： | 2 |
| 4 | Nonradiative dielectric waveguide for millimeter-wave integrated circuits显示文摘 | Yoneyama T Nishida S | 1981 | IEEE Trans Microwave Theory Tech1981，29，11： | 1 |
| 5 | R&D of oxide dispersion strengthened ferritic martensitic steels for FBR显示文摘 | Ukai S Nishida T Okuda T | 1998 | Journal of Nuclear Materials1998，，： | 1 |
| 6 | Length and quality of survival following external beam radiotherapy combined wit h expandable metallic stent for unresectable hilar cholangiocarcinoma显示文摘 | Shinchi H Takao S Nishida H | 2000 | J Surg Oncol2000，75，2： | 1 |
| 7 | Neoendothelialization after peripheral blood stem cell transplantation in humans: a case report of a Tokaimura nuclear accident victim 显示文摘 | Suzuki T Nishida M Futami S | 2003 | Cardiovasc Res2003，58，2： | 1 |
| 8 | Signal separation of background EEG and spike by using morphological filter显示文摘 | NISHIDA S NAKAMURA M IKEDA A | 1999 | Medical Engineering and Physics1999，21，9： | 1 |
| 9 | Effect of c-kit mutation on prognosis of gastrointestinal stromal cell tumors 显示文摘 | TANIGUCHI M NISHIDA T HIROTA S | 1997 | Gastrointest Endosc1997，45，6： | 1 |
| 10 | Epigalloeatechin- 3-gal- late increases the number of neural stem cells around the damaged area after rat traumatic brain injury显示文摘 | hoh T Imano M Nishida S | 2012 | J Neural Transm2012，119，： | 1 |
| 11 | Multidetector CT of high-risk patients with occuh gastrointestinal stromal tumors显示文摘 | Nishida T Kumano S Sugiura T | 2003 | AmJ Roentgenol2003，180，1： | 1 |
| 12 | Molecular detection of disseminated cancer cells in the peripheral blood of patients with gastric cancer 显示文摘 | Kitamura K Ichikawa D | 2000 | Anti cancer Res2000，20，3： | 1 |
| 13 | In vitro culture technique for Cryptocaryon irritans,a parasitic ciliate of marine teleosts显示文摘 | Yoshinaga T Akiyama K Nishida S | 2007 | Dis Aquat Organ2007，78，： | 1 |
| 14 | Human intervertebral disc cells are genetically modifiable by adenovirus-mediated gene transfer:implications for the clinical management of intervertebral disc disorders显示文摘 | MOON S H GILBERTSON L G NISHIDA K | 2000 | Spine2000，25，20： | 1 |
| 15 | Metabolic effects of melatonin on oxidative stress and diabetes mellitus显示文摘 | Nishida S | 2005 | Endocrine2005，27，： | 1 |
| 16 | Feasibility Study of S-1 and In- traperitoneal Docetaxel Combination Chemotherapy for Gastric Cancer with Peritoneal Dissemination 显示文摘 | Fujiwara Y Nishida T Takiguchi S | 2010 | Anticancer Res2010，30，4： | 1 |
| 17 | Neoendothelialization after peripheral blood stem cell transplantation in humans:a case report of a Tokaimura nuclear accident victim显示文摘 | Suzuki T Nishida M Futami S | | 0，，02： | 1 |
| 18 | The effect of TGF-betal on differential gene expression profiles in human corneal epithelium studied by cDNA expression array显示文摘 | Hayashida-Hibino S Watanabe H Nishida K | 2001 | Invest Ophthalmol Vis Sci2001，42，8： | 1 |
| 19 | Trypsin inhibitor activity incommercial soybean products in Japan显示文摘 | MIYAGI Y SHINJO S NISHIDA R | 1997 | Journal of Nutritional Scienceand Vitaminology1997，43，5： | 1 |
| 20 | Connective tissue grow th factor increased by hypoxia may initiate angiogenesis in collaboration w ith matrix metalloprotei-nases显示文摘 | Kondo S Kubota S Shimo T Nishida T Yosimichi G Eguchi T | 2002 | Carcinogenesis2002，23，5： | 1 |
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