|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 孕前血压及其到妊娠早期的变化:先兆子痫和妊娠期高血压的早期危险因素显示文摘先兆子痫和妊娠期高血压是常见的妊娠并发症,与母婴发病率显著相关。尽管对怀孕期间的危险因素进行了广泛的研究,但大多数患妊娠期高血压疾病的妇女并不被认为是高风险的,预防措施仍不清楚。研究者评估了妊娠前的血压及其到妊娠早期的变化,将其作为妊娠高血压疾病发展新的危险标志。 | 刘青(译) 刘莉(摘/审校) Nobles CJ Mendola P Mumford SL Silver RM Kim K Andriessen VC Connell M Sjaarda L Perkins NJ Schisterman EF | 2020 | 中华高血压杂志2020，28，12： | 12 |
| 2 | Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus显示文摘AIM:To assess tumour regression grade(TRG)and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS:Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal junction treated with surgery alone or neoadjuvant chemotherapy and surgery between 2005and 2011 at a single institution were reviewed.Triplet neoadjuvant chemotherapy consisting of platinum,fluoropyrimidine and anthracycline was considered for operable patients(World Health Organization performance status≤2)with clinical stage T2-4 N0-1.Response to neoadjuvant chemotherapy(NAC)was assessed using TRG,as described by Mandard et al.In addition lymph node downstaging was also assessed.Lymph node downstaging was defined by cN1 at diagnosis:assessed radiologically(computed tomography,positron emission tomography,endoscopic ultrasonography),then pathologically recorded as N0 after surgery;ypN0 if NAC given prior to surgery,or pN0if surgery alone.Patients were followed up for 5 years post surgery.Recurrence was defined radiologically,with or without pathological confirmation.An association was examined between t TRG and lymph node downstaging with disease free survival(DFS)and a comprehensive range of clinicopathological characteristics.RESULTS:Two hundred and eighteen patients underwent esophageal resection during the study interval with a mean follow up of 3 years(median follow up:2.552,95%CI:2.022-3.081).There was a 1.8%(n=4)inpatient mortality rate.One hundred and thirty-six(62.4%)patients received NAC,with 74.3%(n=101)of patients demonstrating some signs of pathological tumour regression(TRG 1-4)and 5.9%(n=8)having a complete pathological response.Forty four point one percent(n=60)had downstaging of their nodal disease(cN1 to ypN0),compared to only 15.9%(n=13)that underwent surgery alone(pre-operatively overstaged:cN1 to pN0),(P<0.0001).Response to NAC was associated with significantly increased DFS(mean DFS;TRG 1-2:5.1years,95%CI:4.6-5.6 vs TRG 3-5:2.8 years,95%CI:2.2-3.3,P<0.0001).Nodal down-staging conferred a significant DFS advantage for those patients with a poor primary tumour response to NAC(median DFS;TRG 3-5 and nodal down-staging:5.533 years,95%CI:3.558-7.531 vs TRG 3-5 and no nodal down-staging:1.114 years,95%CI:0.961-1.267,P<0.0001).CONCLUSION:Response to NAC in the primary tumour and in the lymph nodes are both independently associated with improved DFS. | Fergus Noble Luke Nolan Adrian C Bateman James P Byrne Jamie J Kelly Ian S Bailey Donna M Sharland Charlotte N Rees Timothy J Iveson Tim J Underwood Andrew R Bateman | 2013 | World Journal of Gastroenterology2013，19，48： | 4 |
| 3 | Maturation effects on absolute biomarker concentration in a suite of coals and associated vitrinite concentrates 显示文摘 | Dzou L I P Noble R A | 1995 | Org Geochemistry1995，23，7： | 2 |
| 4 | Hyaluronan in tissue injury and repair 显示文摘 | Jiang D Liang J Noble P W | 2007 | Annu Rev Cell Dev Biol2007，23，： | 1 |
| 5 | Fabrication of 'hairy' colloidosomes with shells of polymeric microrods显示文摘 | Noble P F Cayre O J Alargova R G | 2004 | Journal of the American Chemical Society2004，126，26： | 1 |
| 6 | IL-11 receptor | alpha | in the pathogenesis of IL-13-induced inflammation and remodeling显示文摘 | Chen Q Rabach L Noble P | 2005 | J Immunol2005，174，4： | 1 |
| 7 | PTSD and dopaminergic genes, DRD2 and DAT, in muhigenerational families exposed to the Spitak earthquake 显示文摘 | BAILEY J N GOENJIAN A K NOBLE E P | 2010 | Psychiatry Res2010，178，3： | 1 |
| 8 | Industrial pricing, theory and managerial practice 显示文摘 | Noble P M Grucca T S | 1999 | Marketing Science1999，18，3： | 1 |
| 9 | Idiopathie pulmonary, fibrosis:new insights into classi- fication and pathogenesis usher in a new era in therapeutic approaches 显示文摘 | Noble P W | 2003 | Am J Respir Cell Mol Biol2003，29，1： | 1 |
| 10 | Dietary energy intake at the age of 4 months predicts postnatal weight gain and childhood body mass index显示文摘 | Ong K K Emmett P M Noble S | 2006 | Pe- diatrics2006，117，3： | 1 |
| 11 | Citalopram ; A review of its pharmacology, clinical efficacy and tolerability in the treatment of depression显示文摘 | Noble S Benfield P | 1997 | CNS drugs1997，8，： | 1 |
| 12 | UK muhicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal translucency thickness at 10 - 14 weeks of ges- tation显示文摘 | Snijders RJM Noble P Sebire N Souka A Nicolaides KH | 1998 | Lancet1998，351，： | 1 |
| 13 | A forest simulation model for predicting eucalypt dynamics and habitat quality for arboreal marsupials 显示文摘 | Pausas J G Austin M P Noble A R | 1997 | Ecological Applications1997，7，5： | 1 |
| 14 | The Near-infrared Combination and Frequencies of Dioctahedral Smectites, Micas, and Illites显示文摘 | Post J L Noble P N | 1993 | Clays and Clay Minerals1993，41，6： | 1 |
| 15 | Signaling properties of hyaluronan receptors 显示文摘 | Turley E A Noble P W Bourguignon L Y | 2002 | J Biol Chem2002，277，7： | 1 |
| 16 | Second-line or subsequent systemic therapy for recurrent or progressive non-small cell lung cancer:a systematic review and practice guideline显示文摘 | Noble J Ellis P M Mackay J A Evans W K | 2006 | J Thorac Oncol2006，1，： | 1 |
| 17 | Recent patterns and mechanisms of carbon exchange by terrestrial ecosystems显示文摘 | Schimel D S House J I Hibbard K A Bousquet P Ciais P Peylin P Braswell B H Apps M J Baker D Bondeau A Canadell J Churkina C: Cramer W Denning A S Field CB Friedlingstein P Goodale C Heimann M Houghton RA Melillo J M Moore B 3rd Murdiyarso D Noble L Pacala S W Prentice I C Raupach M R Rayner P J Scholes R J Steffen W L Wirth C | 2001 | Nature2001，414，： | 1 |
| 18 | Non-reducing alkaline solubilization and rapid on-column refolding of recombinant prion protein显示文摘 | Walsh D J Noble G P Piro J R | | 0，，01： | 1 |
| 19 | The effect of in vivo mechanical loading on estrogen receptor alpha expression in rat ulnar osteoeytes 显示文摘 | Ehrlich P J Noble B S Jessop H L | 2002 | J Bone MinerRes2002，17，9： | 1 |
| 20 | Limitation of infarct size by trimetazidine in the rabbit 显示文摘 | Noble M I Belcher P R Drake-Holland A J | 1995 | Am J Cardiol1995，76，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员