|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Simplified criteria for diagnosing superficial esophageal squamous neoplasms using Narrow Band Imaging magnifying endoscopy显示文摘AIM To simplify the diagnostic criteria for superficial esophageal squamous cell carcinoma(SESCC) on Narrow Band Imaging combined with magnifying endoscopy(NBI-ME).METHODS This study was based on the post-hoc analysis of a randomized controlled trial. We performed NBI-ME for 147 patients with present or a history of squamous cell carcinoma in the head and neck, or esophagus between January 2009 and June 2011. Two expert endoscopistsdetected 89 lesions that were suspicious for SESCC lesions, which had been prospectively evaluated for the following 6 NBI-ME findings in real time: 'intervascular background coloration'; 'proliferation of intrapapillary capillary loops(IPCL)'; and 'dilation', 'tortuosity', 'change in caliber', and 'various shapes(VS)' of IPCLs(i.e., Inoue's tetrad criteria). The histologic examination of specimens was defined as the gold standard for diagnosis. A stepwise logistic regression analysis was used to identify candidates for the simplified criteria from among the 6 NBI-ME findings for diagnosing SESCCs. We evaluated diagnostic performance of the simplified criteria compared with that of Inoue's criteria.RESULTS Fifty-four lesions(65%) were histologically diagnosed as SESCCs and the others as low-grade intraepithelial neoplasia or inflammation. In the univariate analysis, proliferation, tortuosity, change in caliber, and VS were significantly associated with SESCC(P < 0.01). The combination of VS and proliferation was statistically extracted from the 6 NBI-ME findings by using the stepwise logistic regression model. We defined the combination of VS and proliferation as simplified dyad criteria for SESCC. The areas under the curve of the simplified dyad criteria and Inoue's tetrad criteria were 0.70 and 0.73, respectively. No significant difference was shown between them. The sensitivity, specificity, and accuracy of diagnosis for SESCC were 77.8%, 57.1%, 69.7% and 51.9%, 80.0%, 62.9% for the simplified dyad criteria and Inoue's tetrad criteria, respectively.CONCLUSION The combination of proliferation and VS may serve as simplified criteria for the diagnosis of SESCC using NBIME. | Akira Dobashi Kenichi Goda Noboru Yoshimura Tomohiko R Ohya Masayuki Kato Kazuki Sumiyama Masato Matsushima Shinichi Hirooka Masahiro Ikegami Hisao Tajiri | 2016 | World Journal of Gastroenterology2016，22，41： | 10 |
| 2 | Diagnostic utility of narrow-band imaging endoscopy for pharyngeal superfi cial carcinoma显示文摘AIM: To investigate the endoscopic features of pharyngeal superfi cial carcinoma and evaluate the utility of narrow-band imaging (NBI) for this disease. METHODS: In the present prospective study, 335 patients underwent conventional white light (CWL) en-doscopy and non-magnifi ed/magnifi ed NBI endoscopy, followed by an endoscopic biopsy, for 445 superfi cial lesions in the oropharynx and hypopharynx. The macroscopic appearance of superfi cial lesions was categorized as either elevated (< 5 mm in height), flat, or depressed (not ulcerous). Superficial carcinoma (SC) was defi ned as a superfi cial lesion showing high-grade dysplasia or squamous cell carcinoma on histology. The color, delineation, and macroscopic appearances of the lesions were evaluated by CWL endoscopy. The ratio of the brownish area/intervascular brownish epithelium (IBE), as well as microvascular proliferation, dilation, and irregularities, was determined by non-magnifi ed/ magnifi ed NBI endoscopy. An experienced pathologist who was unaware of the endoscopic fi ndings made the histological diagnoses. By comparing endoscopic fi ndings with histology, we determined the endoscopic features of SC and evaluated the diagnostic utility of NBI. RESULTS: The 445 lesions were divided histologically into two groups: a non-SC group, including non-neoplasia and low-grade dysplasia cases, and an SC group. Of the 445 lesions examined, 333 were classified as non-SC and 112 were classif ied as SC. There were no significant differences in age, gender, or the location of the lesions between the patients in the two groups. The mean diameter of the SC lesions was signif icantly greater than that of non-SC lesions (11.0 ± 7.6 mm vs 4.6 ± 3.6 mm, respectively, P < 0.001). Comparisons of CWL endoscopy fi ndings for SC and non-SC lesions by univariate analysis revealed that the incidence of redness (72% vs 41%, respectively, P < 0.001) and a flat or depressed type of lesion (58% vs 44%, respectively, P = 0.013) was significantly higher in the SC group. Using non-magnifi ed NBI endoscopy, the incidence of a brownish area was signifi cantly higher for SC lesions (79% vs 57%, respectively, P < 0.001). On magnifi ed NBI endoscopy, the incidence of IBE (68% vs 33%, P < 0.001) and microvascular proliferation (82% vs 51%, P < 0.001), dilation (90% vs 76%, P =0.002), and irregularity (82% vs 31%, P < 0.001) was also signifi cantly higher for the SC compared with the non-SC lesions. Multivariate analysis revealed that the incidence of redness (P = 0.022) on CWL endoscopy and IBE (P < 0.001) and microvascular irregularities (P < 0.001) on magnif ied NBI endoscopy was signif icantly higher in SC than non-SC lesions. Redness alone exhibited signifi cantly higher sensitivity and signifi cantly lower specifi city for the diagnosis of SC compared with redness plus IBE and microvascular irregularities (72% vs 52%, P = 0.002; and 59% vs 92%, P < 0.001, respectively). The accuracy of redness plus IBE and irregularities for the diagnosis of SC was signifi cantly greater than using redness alone (82% vs 62%, respectively, P < 0.001). CONCLUSION: Redness, IBE, and microvascular irregularities appear to be closely related to SC lesions. Magnifi ed NBI endoscopy may increase the diagnostic accuracy of CWL endoscopy for SC. | Noboru Yoshimura Kenichi Goda Hisao Tajiri Yukinaga Yoshida Takakuni Kato Yoichi Seino Masahiro Ikegami Mitsuyoshi Urashima | 2011 | World Journal of Gastroenterology2011，17，45： | 7 |
| 3 | Hydrophobic transfer of RTV silicone rubber aged in single and multiple environmental stress and the behavior of LMW silicone fluid显示文摘 | Seiji Kumagai Noboru Yoshimura | 2003 | IEEE Transactions on Power Delivery2003，18，2： | 1 |
| 4 | Hydrophobic transfer of RTV silicone rubber aged in single and multiple environmental stresses and the behavior of LMW silicone fluid显示文摘 | Seiji Kumagai Noboru Yoshimura | 2003 | IEEE Transactions on Power Delivery2003，18，2： | 1 |
| 5 | Hydro phobic transfer of RTV silicone rubber aged in single and multiple enviromental stress and the behavior of LMW silicone fluid显示文摘 | Seiji Kumagai Noboru Yoshimura | 2003 | IEEE Transactions on Power Delivery2003，18，2： | 1 |
| 6 | Ultrathin endoscopy versus high-resolution endoscopy for diagnosing superficial gastric neoplasia显示文摘 | Hirobumi Toyoizumi Mitsuru Kaise Hiroshi Arakawa Jin Yonezawa Yukinaga Yoshida Masayuki Kato Noboru Yoshimura Ken-ichi Goda Hisao Tajiri | 2009 | Gastrointestinal Endoscopy2009，，2： | 1 |
| 7 | Comparison of Methimazole and Propylthiouracil in Patients with Hyperthyroidism Caused by Graves’ Disease显示文摘 | Hirotoshi Nakamura Jaeduk Yoshimura Noh Koichi Itoh Shuji Fukata Akira Miyauchi Noboru Hamada | 2007 | The Journal of Clinical Endocrinology & Metabolism2007，，： | 1 |
| 8 | Ultrathin endoscopy versus high-resolution endoscopy for diagnosing superficial gastric neoplasia显示文摘 | Hirobumi Toyoizumi Mitsuru Kaise Hiroshi Arakawa Jin Yonezawa Yukinaga Yoshida Masayuki Kato Noboru Yoshimura Ken-ichi Goda Hisao Tajiri | 2009 | Gastrointestinal Endoscopy2009，，2： | 1 |
| 9 | Hydro phobic transfer of RTV silicone rubber aged in single and multiple enviromental stress and the behavior of LMW silicone fluid显示文摘 | Seiji Kumagai Noboru Yoshimura | 2003 | IEEE Transactions on Power Delivery2003，18，2： | 1 |
| 10 | Trimodal imaging endoscopy may improve diagnostic accuracy of early gastric neoplasia: a feasibility study显示文摘 | Masayuki Kato Mitsuru Kaise Jin Yonezawa Kenichi Goda Hirobumi Toyoizumi Noboru Yoshimura Yukinaga Yoshida Muneo Kawamura Hisao Tajiri | 2009 | Gastrointestinal Endoscopy2009，，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员