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	题名	作者	年代	出处	被引量
1	Red pigment production by Penicillium purpurogenum GH2 is influenced by pH and temperature显示文摘The combined effects of pH and temperature on red pigment production and fungal morphology were evaluated in a submerged culture of Penicillium purpurogenum GH2, using Czapek-Dox media with D-xylose as a carbon source. An experimental design with a factorial fix was used: three pH values (5, 7, and 9) and two temperature levels (24 and 34 °C) were evaluated. The highest production of red pigment (2.46 g/L) was reached with a pH value of 5 and a temperature of 24 °C. Biomass and red pigment production were not directly associated. This study demon- strates that P. purpurogenum GH2 produces a pigment of potential interest to the food industry. It also shows the feasibility of producing and obtaining natural water-soluble pigments for potential use in food industries. A strong combined effect (p<0.05) of pH and temperature was associated with maximal red pigment production (2.46 g/L).	Alejandro MéNDEZ Catalina PéREZ Julio Cesar MONTAéZ Gabriela MARTíNEZ Cristóbal Noé AGUILAR	2011	Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2011，12，12：	4
2	Frequency and prognostic role of mucosal healing in patients with Crohn's disease and ulcerative colitis after one-year of biological therapy显示文摘AIM:To assess the endoscopic activity before and after a one-year period of biological therapy and to evaluate the frequency of relapses and need for retreatment after stopping the biologicals in patients with Crohn’s disease(CD)and ulcerative colitis(UC).METHODS:The data from 41 patients with CD and 22 patients with UC were assessed.Twenty-four CD patients received infliximab,and 17 received adalimumab.The endoscopic severity of CD was quantified with the simplified endoscopic activity score for Crohn’s disease in CD and with the Mayo endoscopic subscore in UC.RESULTS:Mucosal healing was achieved in 23 CD and7 UC patients.Biological therapy had to be restarted in78%of patients achieving complete mucosal healing with CD and in 100%of patients with UC.Neither clinical remission nor mucosal healing was associated with the time to restarting the biological therapy in either CD or UC.CONCLUSION:Mucosal healing did not predict sustained clinical remission in patients in whom the biological therapies had been stopped.	Klaudia Farkas Péter László Lakatos Mónika Szcs va Pallagi-Kunstár Anita Bálint Ferenc Nagy Zoltán Szepes Noémi Vass Lajos S Kiss Tibor Wittmann Tamás Molnár	2014	World Journal of Gastroenterology2014，20，11：	2
3	益生菌抑制自发性高血压大鼠的菌群失调和血压升高:短链脂肪酸的作用显示文摘该研究旨在评估益生菌短双歧杆菌CECT7263(BFM)及发酵乳酸杆菌CECT5716(LC40)、短链脂肪酸丁酸盐及醋酸盐对自发性高血压大鼠(spontaneously hypertensive rat,SHR)心血管的作用。方法和结果:5周龄的Wistar Kyoto大鼠(WKY)10只和周龄匹配的SHR 50只随机分为6组:对照WKY、对照SHR、BFM干预的SHR、LC40干预的SHR、丁酸盐干预的SHR和醋酸盐干预的SHR。	袁源(译) 练桂丽(审校) Robles-Vera I Toral M de la Visitación N Sánchez M Gómez-Guzmán M Romero M Yang T Izquierdo-Garcia JL Jiménez R Ruiz-Cabello J Guerra-Hernández E Raizada MK Pérez-Vizcaíno F Duarte J	2020	中华高血压杂志2020，28，9：	2
4	New insights into the management of acne: An update from the Global Alliance to Improve Outcomes in Acne Group显示文摘	Diane Thiboutot Harald Gollnick Vincenzo Bettoli Brigitte Dréno Sewon Kang James J. Leyden Alan R. Shalita Vicente Torres Lozada Diane Berson Andrew Finlay Chee Leok Goh María Isabel Herane Ana Kaminsky Raj Kubba Alison Layton Yoshiki Miyachi Montserrat P	2009	Journal of the American Academy of Dermatology2009，，5：	2
5	Treatment for microcarcinoma of the thyroid -clinical experience显示文摘	Kucuk NO Tari P Tokmak E	2007	Clin Nucl Med2007，32，4：	1
6	Antibacterial activity of chitosans and chitosan oligomers with different molecular weights显示文摘	No H K Young Park N Ho Lee S Meyers S P	2002	International Journal of Food Microbiology2002，74，12：	1
7	Effects of pH Neutral, Super-Oxidized Solution on Human Dermal Fibroblasts in vitro显示文摘	Gonz a lez-Espinosa D P e rez-Romano L Guzm a n-Sofia- no B	2007	Int Wound2007，4，3：	1
8	Pancrontic metastasis from renal carcino- ma managed by Whipple resection: a case report and literature re- view of metastatic pattern, surgrial management and outcome 显示文摘	Machado NO Chopra P	2009	JOP2009，10，4：	1
9	A new family of binary pseudorandom sequences having optimal periodic correlation properties and large linear span显示文摘	No J S Kumar P V	1989	IEEE Trans Inform Theory1989，35，2：	1
10	A Lyapunov function ap- proach to longitudinal control of vehicles in a platoon 显示文摘	No T P Chong K T Roh D H	2001	IEEE Transactions on Vehicular Technology2001，50，1：	1
11	Changes on diffusion- weighted MRI with focal motor status epilepticus: case report 显示文摘	Senn P Lvblad NO Zutter D	2003	Neuroradiology2003，45，4：	1
12	2 fuel oil-contaminated soil显示文摘	CAMAN E P CROSSMAN T L GATILIFF E G Phytorernediation of No	1998	Soil contam1998，7，4：	1
13	Crystal structure of the IMP-1 metallo-β-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor显示文摘	Concha NO Janson CA Rowling P	2000	Biochemistry2000，，：	1
14	The skewness of science in 219 sub-fields and a number of aggregates 显示文摘	ALBARRAN P CRESPO J ORTU NO I	2011	Scientometrics2011，88，2：	1
15	Exploring ultrashort high-energy electron-induced damage in hu- man eareinoma cells显示文摘	Rigaud O Fortunel NO Vaigot P	2010	Cell Death Dis2010，，1：	1
16	Antibacterial activity of chitosans and chitosan oligomers with different molecular weights 显示文摘	No H K Park N Y Lee S H Meyers S P	2002	International Journal of Food Microbiology2002，74，12：	1
17	Evaluation using extracted human teeth of Ricetral as a storage medium for avulsions-an in vitro study显示文摘	Rajendran P Varghese NO Varughese JM	2011	Dent Traumatol2011，27，3：	1
18	A new family of binary pseudorandom se- quences having optimal periodic correlation properties and large linear span显示文摘	] No J S Kumar P V	1989	IEEE Transactions on Information Theory1989，，：	1
19	Tendon repair augmented with a novel circulating stem cell population显示文摘	Daher RJ Chahine NO Razzano P		0，，03：	1
20	Human side population keratinocytes exhibit longterm proliferative potential and a specific gene expression profile and can form a pluristratified epidermis 显示文摘	Larderet G Fortunel NO Vaigot P Cegalerba M MaItere P Zobiri 0 et at	2006	Stem Cells2006，24，4：	1

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