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| 1 | Physical activity in primary and secondary prevention of cardiovascular disease:Overview updated显示文摘Although the observed progress in the cardiovascular disease treatment, the incidence of new and recurrent coronary artery disease remains elevated and constitutes the leading cause of death in the developed countries. Three-quarters of deaths due to cardiovascular diseases could be prevented with adequate changes in lifestyle, including increased daily physical activity. New evidence confirms that there is an inverse dose-response relationship between physical activity and cardiovascular disease and mortality risk. However, participation in moderate to vigorous physical activity may not fully attenuate the independent effect of sedentary activities on increased risk for cardiovascular diseases. Physical activity also plays an important role in secondary prevention of cardiovascular diseases by reducing the impact of the disease, slowing its progress and preventing recurrence. Nonetheless, most of eligible cardiovascular patients still do not benefit from secondary prevention/cardiac rehabilitation programs. The present review draws attention to the importance of physical activity in the primary and secondary prevention of cardiovascular diseases. It also addresses the mechanisms by which physical activity and regular exercise can improve cardiovascular health and reduce the burden of the disease. | Alberto J Alves Joao L Viana Suiane L Cavalcante Nórton L Oliveira JoséA Duarte Jorge Mota JoséOliveira Fernando Ribeiro | 2016 | World Journal of Cardiology2016，8，10： | 6 |
| 2 | Giant hepatic extra-gastrointestinal stromal tumor treated with cytoreductive surgery and adjuvant systemic therapy:A case report and review of literature显示文摘BACKGROUND Primary extra-gastrointestinal stromal tumors(E-GIST)of the liver are rare.The clinical presentation may range from asymptomatic to bleeding or manifestations of mass effect.Oncologic surgery followed by adjuvant therapy with imatinib is the standard of care.However,under specific circumstances,a cytoreductive approach may represent a therapeutic option.We describe herein the case of an 84-year-old woman who presented with a tender,protruding epigastric mass.Abdominal computed tomography scan revealed a large,heterogeneous mass located across segments III,IV,V,and VIII of the liver.The initial approach was transarterial embolization of the tumor,which elicited no appreciable response.Considering the large size and central location of the tumor and the advanced age of the patient,non-anatomic complete resection was indicated.Due to substantial intraoperative bleeding and hemodynamic instability,only a near-complete resection could be achieved.Histopathology and immunohistochemical staining confirmed the diagnosis of primary E-GIST of the liver.Considering the risk/benefit ratio for therapeutic options,debulking surgery may represent a strategy to control pain and prolong survival.CASE SUMMARY Here,we present a case report of a patient diagnosed with E-GIST primary of the liver,which was indicated a cytoreductive surgery and adjuvant therapy with imatinib.CONCLUSION E-GIST primary of the liver is a rare conditional,the treatment is with systemic therapy and total resection surgery.However,a cytoreductive surgery will be necessary when a complete resection is no possible. | Michel Ribeiro Fernandes Caroline Lorenzoni Almeida Ghezzi Tomaz J M Grezzana-Filho Flávia Heinz Feier Ian Leipnitz Aljamir Duarte Chedid Carlos Thadeu Schmidt Cerski Marcio Fernandes Chedid Cléber RositoPinto Kruel | 2021 | World Journal of Gastrointestinal Surgery2021，13，3： | 3 |
| 3 | 益生菌抑制自发性高血压大鼠的菌群失调和血压升高:短链脂肪酸的作用显示文摘该研究旨在评估益生菌短双歧杆菌CECT7263(BFM)及发酵乳酸杆菌CECT5716(LC40)、短链脂肪酸丁酸盐及醋酸盐对自发性高血压大鼠(spontaneously hypertensive rat,SHR)心血管的作用。方法和结果:5周龄的Wistar Kyoto大鼠(WKY)10只和周龄匹配的SHR 50只随机分为6组:对照WKY、对照SHR、BFM干预的SHR、LC40干预的SHR、丁酸盐干预的SHR和醋酸盐干预的SHR。 | 袁源(译) 练桂丽(审校) Robles-Vera I Toral M de la Visitación N Sánchez M Gómez-Guzmán M Romero M Yang T Izquierdo-Garcia JL Jiménez R Ruiz-Cabello J Guerra-Hernández E Raizada MK Pérez-Vizcaíno F Duarte J | 2020 | 中华高血压杂志2020，28，9： | 2 |
| 4 | CO2 Emissions Embodied in International Trade:Evidence for Spain显示文摘 | Sanchez C J Duarte R | 2004 | Energy Policy2004，32，18： | 1 |
| 5 | paraquat poisonings:mechanisms of lung toxicity,clinicalfeatures,and treatment显示文摘 | Dinis-Oliveira R J Duarte J A Sanchez-Navarro A | 2008 | Toxicol2008，38，： | 1 |
| 6 | Polymorphisms of the DNA repair genes XRCC1 and XRCC3 in a Brazilian population显示文摘 | Duarte MC Colombo J Rossit AR | 2005 | Genetics and Molecular Biology2005，28，3： | 1 |
| 7 | Three-port triple- half-bridge bidirectional converter with zero-voltage switc- hing 显示文摘 | Tao H Duarte J L Hendrix M A M | 2008 | IEEE Transactions on Power Electronics2008，23，2： | 1 |
| 8 | Surgical results and com- plications in a series of 71 consecutive cervical spondylotic corpec- tomies显示文摘 | Bilbao G Duart M Aurrecoechea J J | 2010 | Acta Neurochir(wien)2010，152，7： | 1 |
| 9 | CO2 emissions embodied in international trade:evidence for Spain显示文摘 | Sánchez-Chóliz J Duarte R | | 0，，18： | 1 |
| 10 | The flavonoid paradox:conjugation and deconjugation as key steps for the biological activity of flavonoids显示文摘 | Perez-Vizcaino F Duarte J Santos-Buelga C | 2012 | J Sci Food Agric2012，92，9： | 1 |
| 11 | Ultra-trace determination of per- sistent organic pollutants in arctic ice using stir bar sorp- tive extraction and gas chromatography coupled to mass spectrometry 显示文摘 | Lacortea S Quintana J Taulera R Ventura F Tovar- Sanchez A Duarte CM | 2009 | J Chromatogr A2009，1216，49： | 1 |
| 12 | Three-port bidirectional converter for hybrid fuel cell systems 显示文摘 | Duarte J L Hendrix M Simoes M G | 2007 | Power Electronics IEEE Transactions on2007，22，2： | 1 |
| 13 | Pliant active and reactive power control for grid-interactive converters under unbalanced voltage dips显示文摘 | WANG F DUARTE J L HENDRIX MAM | 2011 | IEEE Transactions on Power Electronics2011，26，5： | 1 |
| 14 | CO2 emissions embodied in international trade: Evidence for Spain 显示文摘 | Snchez-Ch61iz J Duarte R | 2004 | Energy Policy2004，，18： | 1 |
| 15 | Plumbing the Global Carbon Cycle: integrating inland waters into the terrestrial carbon budget 显示文摘 | Cole JJ Prairie YT Caraco NF McDowell WH Tranvik LJ Striegl RG Duarte CM Kortelainen P Downing JA Middelburg JJ Melack J | 2007 | Ecosystems2007，10，： | 1 |
| 16 | Effect offunctionalized carbon as Pt electrocatalyst support on themethanol oxidation reaction显示文摘 | Salgado J R C Duarte D G Ilharco L M | 2011 | Applied Catalysis B: En-vironmental2011，102，： | 1 |
| 17 | Dexamethasone-loaded scaffolds prepared by supercritical-assisted phase inversion显示文摘 | Duarte A R C Mano J F Reis R L | 2009 | Acta Biomaterialia2009，5，6： | 1 |
| 18 | Pliant active and reactive power control for grid interactive converters under unbalanced voltage dips显示文摘 | Wang F Duarte J Hendrix M | | 0，，05： | 1 |
| 19 | Unifying nutrientchlorophyll relationships in lakes显示文摘 | PRAIRIE Y T DUARTE C M KALFF J | | 0，，： | 1 |
| 20 | Trans- former-coupled muhiport ZVS bidirectional DC-DC converter with wide input range 显示文摘 | TAO Haimin KOTSOPOULOS A DUARTE J L | 2008 | IEEE Transactions on Power Electronics2008，23，2： | 1 |
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