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| 1 | Rubber band ligation for 750 cases of symptomatic hemorrhoids out of 2200 cases显示文摘AIM: To study the results for the treatment of symptomatic hemorrhoids using rubber band ligation (RBL) method. METHODS: A retrospective study for 750 patients who came to the colorectal unit from June, 1998 to September, 2006, data was retrieved from archived fi les. RBL was performed using the Mc Gown applicator on an outpatient basis. The patients were asked to return to out-patient clinic for follow up at 2 wk, 1 mo, 6 mo and through telephone call every 6 mo for 2 years). RESULTS: After RBL, 696 patients (92.8%) were cured with no difference in outcome for second or third degree hemorrhoids (P = 0.31). Symptomatic recurrence was detected in 11.04% after 2 years. A total of 52 patients (6.93%) had 77 complications from RBL which required no hospitalization. Complications were pain, rectal bleeding and vaso-vagal symptoms(4.13%, 4.13% and 1.33% of patients, respectively). At 1 mo there were a significant improvement in mean SF-36 scores over baseline in five items, while after 2 years there were improvement in all items over baseline, but not significant. No significant manometeric changes after band ligation. CONCLUSION: RBL is a simple, safe and effective method for treating symptomatic second and third degree hemorrhoids as an out patient procedure with signifi cant improvement in quality of life. RBL doesn't alter ano-rectal functions. | Ayman M El Nakeeb Amir A Fikry Waleed H Omar Elyamani M Fouda Tito A El Metwally Hosam E Ghazy Sabry A Badr Mohmed Y Abu Elkhar Salih M Elawady Hisham H Abd Elmoniam Waiel W Khafagy Mosaad M Morshed Ramadan E El Lithy Mohamed E Farid | 2008 | World Journal of Gastroenterology2008，14，42： | 24 |
| 2 | Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases显示文摘AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary tumors.METHODS This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.CONCLUSION Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%. | ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab | 2017 | World Journal of Gastroenterology2017，23，38： | 15 |
| 3 | 固氮螺菌(Azosprillum brasilense)NO40在红壤性水稻土上的接种效应显示文摘裂区设计田间试验结果表明 ,在 3个供氮水平下接种巴西固氮螺菌 ( Azospirillum brasilense)NO4 0 ,使分蘖期与灌浆期水稻根际及根内的固氮菌数量均比对照明显增加 ,而土体中的固氮菌数量未见明显变化 ;同时 ,接种该菌株可显著提高分蘖期与灌浆期水稻新展开叶的叶绿素含量及水稻株高 。 | 方萍 张丽梅 贾小明 M N A Omar | 2001 | 浙江大学学报(农业与生命科学版)2001，27，1： | 12 |
| 4 | w显示文摘一系列新 2,5-disubstituted-1,3,4-oxadiazole 和 1,2,4-triazole 衍生物被酸一种肺结核特效药的 heterocyclization 综合 1 和 thiosemicarbazide 衍生物 2。而且,非循环的 C-nucleoside 类似物被反应被他们的相应的糖 hydrazones 的环合与醋性的酐准备。准备混合物的抗菌剂活动被评估,一些综合混合物对真菌揭示了好活动。 | EI-Sayed, Wael A. Ali, Omar M Hendy, Hend A AbdeI-Rahman, Adel A.-H.t | 2012 | Chinese Journal of Chemistry2012，30，1： | 9 |
| 5 | Increased expression of tumor necrosis factor-a is associated with advanced colorectal cancer stages显示文摘AIM:To detect the expression of tumor necrosis factor-a(TNF-a)in colorectal cancer(CRC)cells among Saudi patients,and correlate its expression with clinical stages of cancer.METHODS:Archival tissue specimens were collected from 30 patients with CRC who had undergone surgical intervention at King Khalid University Hospital.Patient demographic information,including age and gender,tumor sites,and histological type of CRC,was recorded.To measure TNF-a m RNA expression in CRC,total RNA was extracted from tumor formalin-fixed,paraffinembedded,and adjacent normal tissues.Reverse transcription and reverse transcription polymerase chain reaction were performed.Colorectal tissue microarrays were constructed to investigate the protein expression of TNF-a by immunohistochemistry.RESULTS:The relative expression of TNF-a m RNA in colorectal cancer was significantly higher than that seen in adjacent normal colorectal tissue.High TNF-a gene expression was associated with StageⅢandⅣneoplasms when compared with earlier tumor stages(P=0.004).Eighty-three percent of patients(25/30)showed strong TNF-a positive staining,while only 10%(n=3/30)of patients showed weak staining,and 7%(n=2/30)were negative.We showed the presence of elevated TNF-a gene expression in cancer cells,which strongly correlated with advanced stages of tumor.CONCLUSION:High levels of TNF-a expression could be an independent diagnostic indicator of colorectal cancer,and targeting TNF-a might be a promising prognostic tool by assessment of the clinical stages of CRC. | Omar A Al Obeed Khayal A Alkhayal Abdulmalik Al Sheikh Ahmad M Zubaidi Mansoor-Ali Vaali-Mohammed Robin Boushey James H Mckerrow Maha-Hamadien Abdulla | 2014 | World Journal of Gastroenterology2014，20，48： | 8 |
| 6 | Role of vitamins in gastrointestinal diseases显示文摘A tremendous amount of data from research was published over the past decades concerning the roles of different vitamins in various gastrointestinal diseases.For instance,most vitamins showed an inverse relationship with the risk of colorectal carcinoma as well as other malignancies like gastric and esophageal cancer in observational trials,however interventional trials failed to prove a clear beneficial preventive role.On the other hand,more solid evidence was obtained from high quality studies for a role of certain vitamins in specific entities.Examples for this include the therapeutic role of vitamin E in patients with nonalcoholic steatohepatitis,the additive role of vitamins B12 and D to the standard therapy of chronic hepatitis C virus,the role of vitamin C in reducing the risk of gallstones,the positive outcome with vitamin B12 in patients with aphthous stomatitis,and the beneficial effect of vitamin D and B1 in patients with inflammatory bowel disease.Other potential uses are yet to be elaborated,like those on celiac disease,pancreatic cancer,pancreatitis,cholestasis and other potential fields.Data from several ongoing interventional trials are expected to add to the current knowledge over the coming few years.Given that vitamin supplementation is psychologically accepted by patients as a natural compound with relative safety and low cost,their use should be encouraged in the fields where positive data are available. | Omar A Masri Jean M Chalhoub Ala I Sharara | 2015 | World Journal of Gastroenterology2015，21，17： | 8 |
| 7 | 培养基铁浓度对不同非共生固氮菌株与小麦基因型联合固氮效率的影响显示文摘采用Spermospheremodels测定5种培养基铁浓度下两株非共生固氮菌(巴西固氮螺菌NO40和多粘芽孢杆菌)及两者的混合菌分别与两个小麦基因型(Giza167和Sakha8)的联合固氮效率,发现培养基的铁浓度对联合固氮效率具有显著的影响.若不考虑菌株间和小麦基因型间的差异,培养基铁浓度在2.583~14.715mg/L时的联合固氮效率显著高于铁浓度为42.883~166.31mg/L;联合固氮效率在小麦基因型间未表现出显著差异,但在不同菌株之间差异极显著.表现为:巴西固氮螺菌>混合菌>多粘芽孢杆菌;联合固氮效率在培养基铁浓度与不同菌株之间存在明显的交互作用,巴西固氮螺菌对铁浓度的适应范围比多粘芽孢杆菌及混合菌广,在固氮高峰期巴西固氮螺菌与小麦基因型Giza167组合的联合固氮效率在5种供试铁浓度下均达较高水平而未表现出显著的差异,巴西固氮螺菌与Sakha8组合的联合固氮效率在铁浓度为2.583~42.883mg/L时最高.说明巴西固氮螺菌NO40对培养基中供铁水平的适应范围较广,因而具有良好的应用前景. | 方萍 A M N Omar | 1997 | 浙江农业大学学报1997，23，6： | 4 |
| 8 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 9 | 腹腔镜与开腹全结肠系膜切除术治疗右半结肠癌的比较显示文摘目的:全结肠系膜切除术(complete mesocolic excision,CME)应用于结肠癌治疗中越来越受欢迎。本研究目的是比较腹腔镜CME(laparoscopic complete mesocolic excision,LCME)和开腹CME(open complete mesocolic excision,OC⁃ME)在右半结肠癌治疗中的可行性、安全性、围手术期并发症以及患者的预后方面的差异。方法:这是一项前瞻性研究,纳入了2012年1月至2019年12月在Assiut大学南方埃及肿瘤中心接受根治性CME右半结肠切除术,术后病理证实为Ⅱ期或Ⅲ期的结肠癌患者作为研究对象。根据手术入路方式的不同将患者分为LCME组(n=48)或OCME组(n=48)。结果:LCME组的平均手术时间明显长于OCME组,平均术中出血量更少。LCME组中有4例(8.3%)患者中转开腹。与OCME组相比,LCME组获取淋巴结数目更多【(39.81±16.74)vs.(32.65±12.28),P=0.010】,第一次排气时间更短,术后进流质饮食和恢复正常饮食的时间更早,术后住院时间更短。LCME组术后并发症发生率为14.7%,略低于OC⁃ME组的27.2%(P=0.252)。LCME组的3年总生存率与OCME组相似(78.2%vs.63.2%,P=0.423)。LCME组3年无疾病进展生存率为74.5%,高于OCME组的60.0%,但差异无统计学意义(P=0.266)。结论:对于专科外科医师,LCME在技术上是安全可行的。对于Ⅱ期或Ⅲ期结肠癌患者,LCME的长期肿瘤预后与OCME相当。 | 杜斌斌 姜雷 ZEDAN A ELSHIEKH E OMAR M I | 2021 | 结直肠肛门外科2021，27，3： | 2 |
| 10 | Synthesis and Invitro Antimicrobial and Antifungul Properties of Some Novel 1,3,4-thiadiazole and s-triazolethiadiazole显示文摘 | Omar A M E Aboulwafa O M | 1986 | Heterocycl Chem1986，23，： | 1 |
| 11 | Magnetic nanocomposites: preparation and characterization of Co-ferrite nanopariticles显示文摘 | Khedr M H Omar A A Abdel-Moaty S A | 2006 | Colloids Surf A2006，281，： | 1 |
| 12 | Interface properties due to microslip from vibration measurement显示文摘 | Sherif H A Omar T M A | 2001 | Journal of Tribology2001，123，1： | 1 |
| 13 | Xanthanolides from Xanthium spinosum 显示文摘 | Omar A A Elrashidy E M Ghazy N A | 1984 | Phytochemistry1984，23，4： | 1 |
| 14 | Evaluation of hand function after early excision and skin grafting of burns versus delayed skin grafting a randomized clinical trial显示文摘 | Omar M T Hassan A A | 2011 | Burns2011，37，4： | 1 |
| 15 | Development of Nonlinear Elastic Leaf Spring Model for MultibodyVehicle Systems显示文摘 | Sugiyama H Shabana A A Omar M A | 2006 | Computer Methods in Applied Mechanics and Engineering2006，195，5051： | 1 |
| 16 | Novel benzothiazole-2- carbomates as potential anthelmintieagents显示文摘 | Omar A M M E Ahmed I C | 2007 | Alexandria J of Pharm Scien2007，21，2： | 1 |
| 17 | Systematic re- view of oncological outcomes following surgical man agement of localised renal cancer显示文摘 | MacLennan S Imanmra M Lapitan M C Omar M I Lain T B Hilvano-Cabungcal A M | 2012 | Eur Urol2012，61，97： | 1 |
| 18 | Cell morphology of extrusion foamed poly(lactic acid)using endothermic chemical foaming agent显示文摘 | Laurent M Matuana Omar Faruk Carlos A Diaz | 2009 | Bioresource Technology2009，100，： | 1 |
| 19 | Multibody system modeling of leaf spring显示文摘 | OMAR M A SHABANA A A MIKKOLA A | | 0，，11： | 1 |
| 20 | Supercritical carbon dioxide (SC-CO2) extraction and fractionation of palm kernel oil from palm kernel as cocoa butter replacers blend显示文摘 | Zaidul I S M Norulaini N A N Omar A K M | | 0，，： | 1 |
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