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526篇 您的检索式：作者名="OWEN J C"

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	题名	作者	年代	出处	被引量
1	p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival显示文摘响应 DNA 损坏的房间命运的中央仲裁人是 p53,它调整涉及房间周期拘捕,幸存和 apoptosis 的基因的表示。尽管 DNA 损坏开始的许多回答被描绘了,肌动朊细胞骨架管理者的角色大部分是未知的。我们现在显示出那 RhoC 和秘鲁利玛机场之代号 kinase (LIMK2 ) 2 是 genotoxic 代理人导致的直接 p53 目标基因。尽管 RhoC 和 LIMK2 在肌动朊细胞骨架规定有生长得很好的角色,我们的结果显示 LIMK2 的激活也有支持幸存的功能追随者 DNA 损坏。由调停 siRNA 的击倒或选择的药理学封锁的 LIMK 抑制敏化房间到无线电 -- 或化疗,以便当与 LIMK 抑制结合了时,当单身地管理了时,是尚不致命的治疗导致了房间死亡。我们的调查结果建议把 LIMK 禁止者与 genotoxic 治疗相结合能比单个代理人的管理更有效,并且加亮在肌动朊细胞骨架管理者和 DNA 之间的一个新奇连接导致损坏的房间幸存机制。	Daniel R Croft Diane Crighton Michael S Samuel Filipe C Lourenco June Munro Jenifer Wood Karim Bensaad Karen H Vousden Owen J Sansom Kevin M Ryan Michael F Olson	2011	Cell Research2011，21，4：	3
2	Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours显示文摘	Owens DM Hulsken J	2002	Development2002，129，1：	1
3	Solid phase microextraction(SPME)combined with gas-chromatography and olfactometry-massspectrometry for characterization ofcheesearoma compounds显示文摘	FRANK D C OWEN C M PATTERSON J	2004	Lebensm-Wiss Technol2004，37，：	1
4	CBF10rthologs in Sour Cherry and Strawberry and The Heterologous Expression of CBFI in Strawberry显示文摘	OWENS C L THOMASHOW M F HANCOCK J F	2002	J Am Soci Hort Sci2002，127，4：	1
5	Feature-based reverse engineering of mechanical parts显示文摘	Thompson W B Owen J C Stark S R	1999	IEEE Transactions on Robotics and Automation1999，15，1：	1
6	The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys 显示文摘	Stremlau M Owens C M Perron M J	2004	Nature2004，427，6977：	1
7	Mapping the sigma70 subunit contact sites on Escherichia coli RNA polymerase with a sigma70-conjugated chemical protease显示文摘	Owens J T Miyake R Meares C F	1998	Proc Natl Aced Sci USA1998，95，：	1
8	Temporal variability of denitrification in estuarine sediments显示文摘	LAW C S REES A P OWENS N J P	1991	Estuarine Coastal and Shelf Science1991，33，1：	1
9	Enhancement of Freezing Tolerance of Strawberry by Heterologous Expression of CBFI显示文摘	OWENS C L LEZZONI A F HANCOCK J F	2003	ActaHort2003，，626：	1
10	Efficacy of anescherichia coli phytase in broilers fed adequate or reducedphosphorus diets and its effect on carcass characteristics显示文摘	Pillai P B Owens C M Emmert J L	2006	Poult Sci2006，85，10：	1
11	Characterization of the resin transfer moulding process显示文摘	KENDALL K N RUDD C D OWEN M J	1992	Composites Manufacturing1992，3，4：	1
12	Neonatal nasal intermittent positive pressure ventilation: a survey of practice in England显示文摘	Owen LS Morley C J Davis PG	2008	Arch Dis Child Fetal Neonatal Ed2008，93，14：	1
13	Volatile compounds in Bacillus-fermented soybeans显示文摘	LEEJEERAJUMNEAN A DUCKHAM S C OWENS J D	2001	Journal of the Science of Food and Agriculture2001，81，5：	1
14	Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture显示文摘	Cory A H Owen T C Barltrop J A	1991	Cancer Commun1991，3，7：	1
15	Nitrous oxide: Estuarine sources and atmospheric flux 显示文摘	LAW C S REES A P OWENS N J P	1992	Estuarine Coastal and Shelf Science1992，35，3：	1
16	Feature-based re- verse engineering of mechanical parts 显示文摘	THOMPSON W B OWEN J C JAMES H	1999	IEEE Transactions on Robotics and Automation1999，15，1：	1
17	SMB: collision detection based on temporal coherence 显示文摘	LI C F FENG Y T OWEN D R J	2006	Computer Methods in Applied Mechanics and Engineering2006，195，1922：	1
18	Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine dependent cell lines显示文摘	Buttke T MeCubrey J A Owen T C	1993	Immunol Methods1993，，：	1
19	Neonatal nasal intermittent positive pres- sure ventilation : A survey of practice in England 显示文摘	Owen LS Morley C J Davis PG	2008	Arch Dis Child Fe- tal Neonatal Ed2008，93，2：	1
20	Late-phase contrast-en- hanced ultrasound reflects biological features of instability in human carotid atherosclerosis显示文摘	Shalhoub J Monaco C Owen DR l	2011	Stroke2011，42，：	1

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