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| 1 | Comprehensive and innovative techniques for livertransplantation in rats: A surgical guide显示文摘AIM: To investigate our learning curves of orthotopic liver transplantation (OLT) in rats and the most important factor for successful surgery. METHODS: We describe the surgical procedures for our rat OLT model, and determined the operator learning curves. The various factors that contributed to successful surgery were determined. The most important surgical factors were evaluated between successful and unsuccessful surgeries.RESULTS: Learning curve data indicated that 50 cases were required for operator training to start a study. Operative time, blood loss, warm ischemic time, anhepatic phase, unstable systemic hemodynamic state, and body temperature after surgery significantly affected surgery success by univariate analysis, while the anhepatic phase was the most critical factor for success by multivariate analysis. CONCLUSION: OLT in rats is the only liver transplantation model that provides clinically relevant and reliable results. Shortened anhepatic phase is key to success in this model. | Tomohide Hori Justin H Nguyen Yasuhiro Ogura Toshiyuki Hata Shintaro Yagi Ann-Marie T Baine Norifumi Ohashi Christopher B Eckman Aimee R Herdt Hiroto Egawa Yasutsugu Takada Fumitaka Oike Seisuke Saka-moto Mureo Kasahara Kohei Ogawa Koichiro Hata Taku Iida Yukihide Yonekawa Lena Sibulesky Kagemasa Kuribayashi Takuma Kato Kanako Saito Mie Torii Naruhiko Sahara Naoko Kamo Tomoko Sahara Motohiko Yasutomi Shinji Uemoto | 2010 | World Journal of Gastroenterology2010，16，25： | 14 |
| 2 | Electromagnetic radiation from rocks 显示文摘 | OGAWA T OIKE K MIURA T | 1985 | Journal of Geophysical Research1985，90，4： | 1 |
| 3 | Neoculin, a tastemodifying protein,is recognized by human sweet taste receptor显示文摘 | Nakajima K Asakura T Oike H | 2006 | Neuroreort2006，17，12： | 1 |
| 4 | Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice 显示文摘 | Yamauchi T Oike Y Kamon J | 2002 | Nat Genet2002，30，： | 1 |
| 5 | Increased insulin sensitivity despite lipo - dystrophy in crebbp heterozygous mice 显示文摘 | Yamauchi T Oike Y Kamon J | 2002 | Nat Genet2002，30，： | 1 |
| 6 | Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases 显示文摘 | Kadomatsu T Tabata M Oike Y | 2011 | FEBS J2011，278，4： | 1 |
| 7 | Hematopoiesis and angiogenesis显示文摘 | Suda T Takakura N Oike Y | 2000 | Int J Hematol2000，71，2： | 1 |
| 8 | Hematopoiesis and angiogenesis显示文摘 | Suda T Takakura N Oike Y | 2000 | Int J Hematol2000，71，： | 1 |
| 9 | Angiopoietinl promotes LYVE-l-positive lymphatic vessel formation 显示文摘 | Morisada T Oike Y Yamada Y | 2005 | Blood2005，105，12： | 1 |
| 10 | Radiotherapy plus con- comitant adjuvant temozolomide for glioblastoma:Japanese mono-in- stitutional results 显示文摘 | OIKE T SUZUKI Y SUGAWARA K | 2013 | Plos One2013，8，78： | 1 |
| 11 | Electromagnetic radiation from rocks显示文摘 | OIKE K | 1985 | J Geophys Res1985，90，4： | 1 |
| 12 | An ultramicroelectrode for determination of intracellular oxygen:light_irradiation_induced change in oxygen concentration in algal protoplast Biochim显示文摘 | Matsue T Oike S Abe T | 1992 | Biophy Acta1992，1101，： | 1 |
| 13 | Endoplasmic reticulum stress -related inflammation and cardiovascular diseases显示文摘 | GOTOH T ENDO M OIKE Y | 2011 | Int J Inflam2011，2011，25： | 1 |
| 14 | Hematopoiesis and angiogeneisis显示文摘 | Takakura N Oike Y | 2000 | Int J HeMatol2000，，71： | 1 |
| 15 | Hematopoiesis and angiogenesis显示文摘 | Suda T Takakura N Oike Y | 2000 | Int J Hematol2000，71，2： | 1 |
| 16 | The role of angiopoietin-like proteins in angiogenesis and metabolism显示文摘 | Hato T Tabata M Oike Y | 2008 | Trends Cardiovasc Med2008，18，1： | 1 |
| 17 | Garcinol,a histone acetyltransferase inhibitor,radiosensitizes cancer cells by inhibiting non-homologous end joining显示文摘 | Oike T Ogiwara H Torikai K | 2012 | Radiation Oncology2012，84，3： | 1 |
| 18 | Suppression of choroidal neovascularization by inhibiting angiotensin-converting enzyme :minimal role of bradyldnin 显示文摘 | Nagai N Oike Y izumi Nagai K Koto T Satofuka S Shinoda H | 2007 | Invest Ophthalmol Vis Sci2007，48，5： | 1 |
| 19 | Hematopoiesis and angiogenesis显示文摘 | Suda T Takakura N Oike Y | 2000 | Int J Hematol2000，71，： | 1 |
| 20 | Correlation between HIV disease and lipid metabolism in antiretroviral-na? ve HIV-infected pa- tients in Japan 显示文摘 | Oka F Naito T Oike M | 2012 | J Infect Chemotber2012，18，1： | 1 |
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