5篇
您的检索式：作者名="Olufunmilayo Olopade"
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| 1 | Race, the microbiome and colorectal cancer显示文摘In the past decade,more cancer researchers have begun to understand the significance of cancer prevention,which has prompted a shift in the increasing body of scientific literature.An area of fascination and great potential is the human microbiome.Recent studies suggest that the gut microbiota has significant roles in an individual’s ability to avoid cancer,with considerable focus on the gut microbiome and colorectal cancer.That in mind,racial disparities with regard to colorectal cancer treatment and prevention are generally understudied despite higher incidence and mortality rates among Non-Hispanic Blacks compared to other racial and ethnic groups in the United States.A comprehension of ethnic differences with relation to colorectal cancer,dietary habits and the microbiome is a meritorious area of investigation.This review highlights literature that identifies and bridges the gap in understanding the role of the human microbiome in racial disparities across colorectal cancer.Herein,we explore the differences in the gut microbiota,common short chain fatty acids produced in abundance by microbes,and their association with racial differences in cancer acquisition. | Kendra J Royston Babatunde Adedokun Olufunmilayo I Olopade | 2019 | World Journal of Gastrointestinal Oncology2019，11，10： | 4 |
| 2 | Colorectal Cancer and Race: Understanding the Differences in Outcomes Between African Americans and Whites显示文摘 | Blase N. Polite James J. Dignam Olufunmilayo I. Olopade | 2005 | Medical Clinics of North America2005，，4： | 1 |
| 3 | Clinical implications of ERβ methylation on sporadic breast cancers in Chinese women显示文摘 | Lin Zhao Zhaojin Yu Yunan Li Xiaoyan Wen Wenfeng Ma Lin Wang Jie Ren Caigang Liu Miao He Xuefeng Bai Mingli Sun Zhihong Zheng Xiaoyi Mi Enhua Wang Olufunmilayo I. Olopade Feng Jin Minjie Wei | 2012 | Medical Oncology2012，，3： | 1 |
| 4 | The role of tumor-associated macrophages in breast cancer progression(Review)显示文摘 | Elias Obeid Rita Nanda Yang-Xin Fu Olufunmilayo Olopade | 2013 | International Journal of Oncology2013，，1： | 1 |
| 5 | Assessment of humoral immunity and nutritionally essential trace elements in steady-state sickle cell disease Nigerian children before and after Prevenar 13 pneumococcal vaccination显示文摘Background:Children with sickle cell disease(SCD)are particularly prone to pneumococcal infection and administration of Prevenar 13 pneumococcal vaccine in Nigerian children with SCD is yet to be wide spread.This call for the need to study humoral immune responses stimulated by Prevenar 13 pneumococcal vaccine in SCD children to confirm the benefit or otherwise for the use of Prevenar 13 pneumococcal vaccine.Method:The levels of humoral(innate and adaptive)immune factors and associated nutritionally essential trace elements were determined following Prevenar 13 pneumococcal vaccination of 23 Nigerian children with SCD.Serum innate humoral immune factors[Complement factors(C1q and C4),transferrin,ferritin,and C-reactive protein(CRP)]and adaptive humoral immune factors[IgG,IgA,IgM,and IgE]were determined using ELISA.Nutritionally essential trace elements such as iron(Fe),copper(Cu),and zinc(Zn)were measured also using an atomic absorption spectrophotometer.Results:The serum levels of certain innate humoral immune factors(ferritin,CRP,and C4),only one adaptive humoral immune factors(IgE),and essential trace elements(Fe,Zn,and Cu)were significantly elevated in children with SCD post Prevenar 13 pneumococcal vaccination when compared to prevaccination levels.Conclusion:Vaccination of children with SCD with Prevenar 13 pneumococcal vaccine was associated with increased levels of more innate humoral immune factors than adaptive factors.This study thus supports the administration of Prevenar 13 pneumococcal vaccination to children with SCD. | Ganiyu Olatunbosun Arinola Elizabeth Disu Adedokun Babatunde Christopher Olopade Olufunmilayo Olopade | 2022 | Blood Science2022，4，3： | 0 |
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