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118篇 您的检索式:作者名="P O Steven"
    题名 作者 年代 出处 被引量
1MicroRNA regulation of innate immune responses in epithelial cells显示文摘Mucosal surface epithelial cells are equipped with several defense mechanisms that guard against pathogens.Recent studies indicate that microRNAs(miRNAs)mediate post-transcriptional gene suppression and may be a critical component of the complex regulatory networks in epithelial immune responses.Transcription of miRNA genes in epithelial cells can be elaborately controlled through pathogen recognition receptors,such as Toll-like receptors(TLRs),and associated nuclear factor kappaB(NF-kB)and mitogen-activated protein kinase(MAPK)pathways,and ultimately nuclear transcription factor associated-transactivation and transrepression.Activation of these intracellular signaling pathways may also modulate the process of miRNA maturation.Functionally,miRNAs may modulate epithelial immune responses at every step of the innate immune network,including production and release of cytokines/chemokines,expression of adhesion and costimulatory molecules,shuttling of miRNAs through release of exosomes and feedback regulation of immune homeostasis.Therefore,miRNAs act as critical regulators to the fine-tuning of epithelial immune responses.Rui Zhou Steven P O’Hara Xian-Ming Chen 2011Cellular & Molecular Immunology2011,8,5:13
2Lithoautotrophic microbial ecosystems in deep basalt aquifers显示文摘Todd O Stevens James P McKinley 1995Science1995,270,:1
3Evolutionary structural optimization(ESO)using a bi-directional algorithm显示文摘 Steven G P Xie Y M 1998Engi-neering Computation1998,15,8:1
4A simple checkerboard suppression algorithm for evolutionary structural optimization 显示文摘Li O Steven G P Xie Y M 2001Structural and Multidisciplinary Optimization2001,22,3:1
5Computational effi-ciency and validation of bi-directional evolutionary structural optimization显示文摘 Young V Steven G P 2000Computer methods in applied mechanics and engineering2000,189,:1
6Compu- tational efficiency and validation of bi-directionaI evo- lutionary structural optimisation显示文摘Querin O M Young V Steven G P Xie Y M 2000Computer Meth- ods in Applied Mechanics and Engineering2000,189,:1
7Computational efficiency and validation of bi-direetional evolutionary structural optimization 显示文摘Querin O M Young V Steven G P Xie Y M 2000Computer Methods in Applied Mechanics and Engineering2000,189,:1
8Lithoautotrophic microbial ecosystem in deep basalt aquifers 显示文摘Steven T O McMkinley J P 1995Science1995,270,5235:1
9Cystic fibrosis显示文摘Brian P O’Sullivan Steven D Freedman 2009The Lancet . 2009 (9678)2009,,:1
10Improving efficiency of evolutionary structural optimization by implementing fixed grid mesh 显示文摘Kim H Querin O M Steven G P 2003Structural and Multidisciplinary Optimization2003,24,6:1
11Identification of an HIV-1 Mutation in Spacer Peptide 1That Stabilizes the Immature CASP1Lattice显示文摘Fontana J Keller P W Urano E Ablan S D Steven A C Freed E O 2016J Virol2016,90,2:1
12Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans显示文摘Rhee Eugene P Cheng Susan Larson Martin G Walford Geoffrey A Lewis Gregory D McCabe Elizabeth Yang Elaine Farrell Laurie Fox Caroline S O’Donnell Christopher J Carr Steven A Vasan Ramachandran S Florez Jose C Clish Clary B Wang Thomas J Ger 2011Journal of Clinical Investigation2011,,4:1
13A simple evolutionary procedure for structural optimization 显示文摘XIE Y M STEVEN O P 1993Computers and Structures1993,49,5:1
14The density of viable seed of forest plantation in uplands Britain 显示文摘Hill M O Steven P A 1981Journal Ecology1981,69,:1
15Sonic anemometer tilt correction algorithms显示文摘James M W P O Steven A S Steven 2001Boundary-Layer Meteor2001,99,:1
16Molecular epidemiology and evolution of en/erovlrus 71 strains isolated from 1970 to 1998 显示文摘BROWN B A STEVEN O M ALEXANI)ER J P 1999J Virol1999,73,12:1
17Structual application of a shape optimization method based on a genetic algorithm 显示文摘Woon S Y Querin O M Steven G P 2005Struct Muhidisc Optim2005,22,:1
18Structural application of a shape optimization method based on a genetic algorithm 显示文摘S Y Woon O M Querin and G P Steven Struct Multidisc Optim0,22,:1
19Stress based optimization of torsional shafts using an evolutionary procedure显示文摘LI Qing STEVEN G P QUERIN O M 2001International Journal of Solids and Structures2001,38,:1
20Interactions of corporate financing and investment decisions: The effects of agency conflicts 显示文摘Childs P D Mauer D C Steven H O 2005Journal of Financial Economics2005,76,:1
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