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| 1 | 直肠癌术后低位前切除综合征的发生率及其对生活质量的影响:一项基于人群的研究显示文摘背景:据报道,直肠癌术后严重的低位前切除综合征(low anterior resection syndrome, LARS)的发生率为17.8%~56.0%,但来自高质量研究的数据较少。本项研究的目的是在一个大型的、明确的、基于人群的队列研究中,确定LARS的发生率及其与患者生活质量(quality of life,Qo L)的关系。方法:这是一项基于人群的队列研究,纳入了2007年至2013年在瑞典斯德哥尔摩市所有接受直肠系膜全部或部分切除的直肠癌根治术的患者。 | 佟伟华(评论) PIENIOWSKI E H A NORDENVALL C PALMER G | 2020 | 结直肠肛门外科2020，26，4： | 5 |
| 2 | Changes in efficiency and resource utilization after increasing experience with double balloon enteroscopy显示文摘AIM:To investigate changes in efficiency and resource utilization as a single endoscopist's experience increased with each subsequent 100 double balloon enteroscopy(DBE) procedures.METHODS:We reviewed consecutive DBE procedures performed by a single endoscopist at our center over 4 years.DBE was employed when the clinician deemed the procedure was needed for disease management.The approach(oral,anal or both) was chosen based on suspected location of the target lesion.All DBE was performed in a standard endoscopy room with a portable fluoroscopy unit.Fluoroscopy was used to aid in shortening the small intestine and reducing bowel loops.For oral DBE,measurements were taken from the incisors.For anal DBE,measurements were taken from the anal verge.Enteroscopy continued until the target lesion was reached,until the entire small intestine was examined,or until no further progress was deemed possible.The length of small intestine examined(cm),procedure duration(min),and fluoroscopy time(s) were analyzed for sequential groups of 100 DBE.Sub-groups of diagnostic and therapeutic procedures were analyzed using multivariable linear regression.RESULTS:802 consecutive DBE procedures were analyzed.For oral DBE,median [interquartile range(IQR)] length of small bowel examined was 230.8 cm(range:210-248 cm) and for anal DBE was 143.5 cm(range:100-180 cm).No significant increase in length examined was noted for either the oral or anal approach with advancing position in series.In terms of duration of procedure,the median(IQR) for oral DBE was 86 min(range:71-105 min) and for anal DBE was 81.3 min(range:67-105 min).When comparing by the position in series,there was a significant(P value < 0.001) decrease in procedure duration for both upper and lower procedures with increasing experience.Median(IQR) time of exposure to fluoroscopy for oral DBE was 190 s(114-275) compared to anal DBE which was 196.4 s(312-128).This represented a significant(P value < 0.001) decrease in the amount of fluoroscopy used with increasing position in series.For both oral and anal DBE,fluoroscopy time was reduced by greater than 50% over the course of 802 total procedures performed.Sub-group analysis was conducted on therapeutic and diagnostic groups.Out of 802 procedures,a total of 434 were considered therapeutic.Argon plasma coagulation was by far the most common therapeutic intervention performed.There was no evidence of a difference in length examined or fluoroscopy exposure among oral DBE for diagnostic and therapeutic procedures,P = 0.91 and P = 0.32 respectively.The median(IQR) for length was 235 cm(range:178-280 cm) for diagnostic vs 230 cm(range:180-275 cm) for therapeutic procedures;additionally,fluoroscopy time median(IQR) was 180 s(range:110-295 s) and 162 s(range:102-263 s) for no intervention and intervention.However,there was a significant difference in procedure duration among oral DBE(P < 0.001).The median(IQR) was 80 min(range:60-97 min) and 94 min(range:77-110 min) for diagnostic and therapeutic interventions respectively.CONCLUSION:For a single endoscopist,increased DBE experience with number of performed procedures is associated with increased efficiency and decreased resource utilization. | Neal C Patel William C Palmer Kanwar R Gill David Cangemi Nancy Diehl Mark E Stark | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，3： | 2 |
| 3 | Diagnosis of in- vasive aspergillosis in bone marrow transplant recipients by polymer- ase chain reaction显示文摘 | Williamson E C Lee ming J P Palmer H M | 2000 | Br J Haematol2000，108，： | 1 |
| 4 | Evaluation of clinical management of gonorrhoea using enhanced surveillance in South East Queensland 显示文摘 | Field E Heel K Palmer C | 2010 | Sex Health2010，7，4： | 1 |
| 5 | Failure of passive immunoglobulin transfer:a major determinant of mortality in newborn alpacas (Lama pacos)显示文摘 | Garmendia A E Palmer G H DeMartini J C | | 0，，： | 1 |
| 6 | Sahel rainfall and worldwide sea surface temperatures显示文摘 | Palmer T N Parker D E | 1986 | Nature1986，320，： | 1 |
| 7 | Development of the human infant intestinal microbiota显示文摘 | Palmer C Bik E M DiGiulio D B et at | 2007 | PLoS Biol2007，5，： | 1 |
| 8 | Diagnosis of inva- sive aspergillosis in bone marrow transplant recipients by poly- merase chain reaction显示文摘 | Williamson E C Leeming J P Palmer H M | 2000 | Br J Haematol2000，108，1： | 1 |
| 9 | Acoustic e- mission monitoring of fatigue crack growth显示文摘 | Lindley T C Palmer I G Richards C E | | Mate- rials Science and Engineering0，32，1： | 1 |
| 10 | TheAnaplasma marginale rasp5 gene encodes a 19-kilodalton protein conserved in all recognized Anaplasma species显示文摘 | Visser E S Mcguire T C Palmer G H | 1992 | Infect Immun1992，60，： | 1 |
| 11 | House fly Head GABA - ga- ted chloride channel: four putative insecticide binding sites differ- entiated by EBOB and TBPS显示文摘 | Yanli Deng Palmer C J Casida J E | 1993 | Pesticide Biochem- istry and Physiology1993，47，： | 1 |
| 12 | Development of the human infant intestinal microbiota显示文摘 | Palmer C Bik E M DiGiulio D B | 2007 | PLoS Biol2007，5，： | 1 |
| 13 | Control of photoresist properties: a Kalman filter based approach 显示文摘 | PALMER E REN W SPANOS C J | 1996 | IEEE Transactions on Semiconductor Manufacturing1996，9，2： | 1 |
| 14 | Effects of kinetin on tuber formationon isolated stolons of Solarium tuberosum cultured in vitro显示文摘 | PALMER C E SMITH O E | 1970 | Plant and Cell Physiology1970，11，： | 1 |
| 15 | Enhanced shoot regeneration from Brassica campestris by silver nitrate 显示文摘 | Palmer C E | 1992 | Plant Cell Reports1992，11，： | 1 |
| 16 | Using Positional Data from Vessel Monitoring Systems to Validate the Logbook-Reported Area Fished and the Stock Allocation of Commercial Fisheries Landings显示文摘 | Palmer M C Wigley S E | 2009 | North American Journal of Fisheries Management2009，29，4： | 1 |
| 17 | Physiological hyperglycemia slows gastric emptying in normal subjects and patients with insulin-dependent diabetes mellitus显示文摘 | E Schvarcz M Palmer J Aman M Horowitz M Stridsberg C Berne | 1997 | Gastroenterology1997，，1： | 1 |
| 18 | Leaching of chalcopyrite and sphalerite using bacteria enriched from a spent chalcocite heap 显示文摘 | KEELING S E PALMER M L CARACATSANIS F C JOHNSON J A WATLING H R | 2005 | Minerals Engineering2005，18，： | 1 |
| 19 | Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor显示文摘 | Palmer A E Jin C Reed J C Tsien R Y | 2004 | Proc Natl Acad Sci USA2004，102，17： | 1 |
| 20 | Moninring fluctuations in nasal patency in children:acoustic rhinometry versus rhinohygrometry显示文摘 | Fisher E W Palmer C R Lund V J | 1995 | J Laryngol Otol1995，109，6： | 1 |
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