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| 1 | Nutrition, insulin resistance and dysfunctional adipose tissue determine the different components of metabolic syndrome显示文摘Obesity is an excessive accumulation of body fat that may be harmful to health. Today, obesity is a major public health problem, affecting in greater or lesser proportion all demographic groups. Obesity is estimated by body mass index(BMI) in a clinical setting, but BMI reports neither body composition nor the location of excess body fat. Deaths from cardiovascular diseases, cancer and diabetes accounted for approximately 65% of all deaths, and adiposity and mainly abdominal adiposity are associated with all these disorders. Adipose tissue could expand to inflexibility levels. Then, adiposity is associated with a state of low-grade chronic inflammation, with increased tumor necrosis factor-α and interleukin-6 release, which interfere with adipose cell differentiation, and the action pattern of adiponectin and leptin until the adipose tissue begins to be dysfunctional. In this state the subject presents insulin resistance and hyperinsulinemia, probably the first step of a dysfunctional metabolic system. Subsequent to central obesity, insulin resistance, hyperglycemia, hypertriglyceridemia, hypoalphalipoproteinemia, hypertension and fatty liver are grouped in the so-called metabolic syndrome(MetS). In subjects with MetS an energy balance is critical to maintain a healthy body weight, mainly limiting the intake of high energy density foods(fat). However, high-carbohydrate rich(CHO) diets increase postprandial peaks of insulin and glucose. Triglyceride-rich lipoproteins are also increased, which interferes with reverse cholesterol transport lowering highdensity lipoprotein cholesterol. In addition, CHO-rich diets could move fat from peripheral to central deposits and reduce adiponectin activity in peripheral adipose tissue. All these are improved with monounsaturated fatty acid-rich diets. Lastly, increased portions of ω-3 and ω-6 fatty acids also decrease triglyceride levels, and complement the healthy diet that is recommended in patients with MetS. | Juan Antonio Paniagua | 2016 | World Journal of Diabetes2016,7,19: | 14 |
| 2 | 磺酸多相催化剂用于二甲基亚砜中C_6-单糖脱水制5-羟甲基糠醛(英)显示文摘Sulfonic acid-functionalized heterogeneous catalysts have been evaluated in the catalytic dehydration of C(,monosaccharides into 5-hydroxymethylfurfural(HMF) using dimethyl sulfoxide(DMSO)as solvent.Sulfonic commercial resin Amberlyst-70 was the most active catalyst,which was ascribed to its higher concentration of sulfonic acid sites as compared with the other catalysts,and it gave 93 mol%yield of HMF from fructose in 1 h.With glucose as the starting material,which is a much more difficult reaction,the reaction conditions(time,temperature,and catalyst loading) were optimized for Amberlyst-70 by a response surface methodology,which gave a maximum HMF yield of 33 mol%at 147 °C with 23 wt%catalyst loading based on glucose and 24 h reaction time.DMSO promotes the dehydration of glucose into anhydroglucose,which acts as a reservoir of the substrate to facilitate the production of HMF by reducing side reactions.Catalyst reuse without a regeneration treatment showed a gradual but not very significant decay in catalytic activity. | Gabriel Morales Juan A.Melero Marta Paniagua Jose Iglesias Blanca Hernandez Maria Sanz | 2014 | 催化学报2014,35,5: | 4 |
| 3 | Effects of high-efficiency postdilution online hemodiafiltration and high-flux hemodialysis on serum phosphorus and cardiac structure and function in patients with end-stage renal disease显示文摘 | Rodríguez Castellanos Francisco Meave Aloha Paniagua Sierra Ramón | 2013 | International Urology and Nephrology2013,,5: | 3 |
| 4 | Design and optimization of supersonic turbines for detonation combustors显示文摘Detonation-based engines offer a potential surge in efficiency for compact thermal power systems. However, these cycles require ad-hoc components adapted to the high outlet velocity from the detonation combustors. This paper presents the design methodology of turbine stages suitable for supersonic inlet conditions and provides a detailed analysis of optimized turbine geometries. A reduced-order solver examines the supersonic blade rows’ functional design space, quantifies the turbine’s non-isentropic performance, and budgets the turbine loss for different optimized leading-edge designs and chord to pitch ratios. The shock-wave interactions were identified as the predominant contributor to turbine losses, and optimal pitch-chord ratios were determined for various inlet Mach numbers. Finally, with this tool, the specific-power output for a wide range of design configurations was computed;and the metal angle that ensures flow starting and maximizes power extraction was calculated. The detailed numerical study describes the flow interactions in a supersonic turbine and offers new correlations to guide the design of future supersonic turbines. | Jorge SOUSA Elena COLLADO-MORATA Guillermo PANIAGUA | 2022 | Chinese Journal of Aeronautics2022,35,11: | 2 |
| 5 | Induction of labor with miso-prostol 显示文摘 | Bugnon A Paniagua AE Postiglione G | 1994 | Gyneool Obstet Mex1994,62,4: | 1 |
| 6 | Relationship of Soil Characteristics to Vegetation Succes- sions on Asequence of Degraded and Rehabilitated Soils in Honduras 显示文摘 | PANIAGUA A KAMMERBAYUER J AVEDILLO M | 1999 | Agriculture Ecosystems and Environment1999,72,: | 1 |
| 7 | Regional transient oste- oporosis of the foot and ~tamin C deficiency显示文摘 | Rodriguez S Paniagua O Nugent KM et ai | 2007 | Clinheumato2007,26,6: | 1 |
| 8 | Health-related quality of life predicts outcomes but is not affected by peritoneal clearance:The ADEMEX trial显示文摘 | Ramon Paniagua Dante Amato Edward Vonesh | 2005 | Kidney International2005,67,: | 1 |
| 9 | Predictive value ofnatriuretic peptides in patients on peritoneal dialysis:results from theADEMEX trial显示文摘 | Paniagua R Amato D Vonesh E | 2008 | Clin J Am Soc Nephrol2008,3,2: | 1 |
| 10 | Uncomplicated general anesthesia in the elderly results in cognitive decline:does cognitive decline predict morbidity and mortality显示文摘 | Lewis MC Nevo I Paniagua MA | | 0,,03: | 1 |
| 11 | Induction of labor with misoprostol显示文摘 | Bugnon A Paniagua AE Postiglione G | 1994 | Gynecol Obstet Mex1994,62,4: | 1 |
| 12 | Predictive value of brain natriuretic peptides in patients on peritoneal dialysis: results from the ADF31EX trial显示文摘 | Paniagua R Amato D Mujais S | 2008 | Clin J Am Soc Nephrol2008,3,: | 1 |
| 13 | NT-proBNP fluid volume overload and dialysis modality are independent predictors of mortality in ESRD patients显示文摘 | Paniagua R Ventura MD Avila-Diaz M | 2010 | Nephrol Dial Transplant2010,25,2: | 1 |
| 14 | Effects of increased peritoneal clearances on mortality rates in peritoneal dialysis: ADEMX, a prospective randomized, controlled trial显示文摘 | RAMON PANIAGUA KANTE AMATO EDWARD VONESH | 2002 | Am Soc Nephrol2002,13,: | 1 |
| 15 | Effects of increased Peritoneal clearances on mortality rates in peritoneal dialysis:ADEMEX, a prospective , randomized, controlled trial显示文摘 | Ramon Paniagua Kante Amato Edward Vonesh | 2002 | J Am Soc Nephrol2002,13,: | 1 |
| 16 | Testicular mierolithiasis in 2 children with bilateral eryptorchidism 显示文摘 | NISTAL M PANIAGUA R DIEZ-PARDO J A | 1979 | J Uro11979,121,: | 1 |
| 17 | Investigation of the unsteady rotor aerodynamics in a transonic turbine Stage显示文摘 | Denos R Arts T Paniagua G | 2001 | ASME Journal of Turbomachinery2001,123,: | 1 |
| 18 | Quantum Study of the Li + HF → LiF + H Reaction显示文摘 | AGUADO A PANIAGUA M LARA M RONCERO O | 1997 | Journal of Chemi- cal Physics1997,107,10: | 1 |
| 19 | Effect of betalactamase inhibitors on minimum inhibitory concentration of ampicillin and amoxicillin for Staphylococcus attreus strains 显示文摘 | Monroy E Garcia O | 1998 | Rev Latinoam Microbiol1998,40,34: | 1 |
| 20 | Predictive value of brain natriuretic peptides in patients on peritoneal dialysis:resuits from the ADEMEX trial显示文摘 | Paniagua R | | 0,,: | 1 |