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| 1 | Homocysteine and copper interact to promote type 5 phosphodiesterase expression in rabbit cavernosal smooth muscle cells显示文摘瞄准:在类型 5 phosphodiesterase (PDE5 ) 上学习人半胱氨酸和铜的效果在 cavernosal 的表示脉管的光滑的肌肉房间(CVSMC ) 并且调查超级氧化物(当人半胱氨酸和铜产生 O 2 · −, 和 O 2 · − 在上面, O 2 · −) 源于菸碱腺嘌 dinucleotide 磷酸盐 oxidase 调整 PDE5 表示。方法:从兔子阴茎导出的 CVSMC 与人半胱氨酸或铜氯化物被孵化与或没有超级氧化物为 16 h 的 dismutase (草皮)( 菸碱腺嘌 dinucleotide 磷酸盐禁止者) ,过氧化氢酶, sildenafil 柠檬酸盐,或 apocynin。PDE5 并且 glyceraldehyde-3-phosphate 脱氢酶(内部标准) 的表示用西方的污点分析被估计。在平行, O 2 · − spectrophotometrically 被测量。结果:CuCl 2 独自一个(多达 10 μmol/L ) 并且(多达 100 μmol/L ) 人半胱氨酸独自没与控制相比在 CVSMC 在 O 2 · − 形成上有效果。然而,当在一样的时间功课上共同孵化时,在联合,人半胱氨酸和 CuCl 2 显著地增加了 O 2 · − 形成,草皮堵住的效果,过氧化氢酶, apocynin,和 sildenafil (1 μmol/L ) 。PDE5 表示显著地也在与控制相比与人半胱氨酸和 CuCl 2, 孵化的 CVSMC 被增加。这效果被 16-h 合作孵化也与草皮,过氧化氢酶, apocynin 和 sildenafil 否定。结论:这代表位于编辑下面的新奇病原的机制,并且显示延长 sildenafil 使用的治疗学的行动通过这条小径的抑制部分地被调停。 | Matthew Hotston Jamie Y. Jeremy Jonathon Bloor Nick S. Greaves Raj Persad Gianni Angelini Nilima Shukla | 2008 | Asian Journal of Andrology2008，10，6： | 7 |
| 2 | The penile tourniquet显示文摘止血带通常在阴茎外科被使用完成一个不流血的操作领域或 intraoperatively 产生人工的勃起。几种技术被描述了,但是有数据的少量和指南的缺乏指导他们的安全使用。在阴茎外科,它是是主要担心的止血带使用的本地而非全身的效果。止血带时间应该被坚守最小,当可得到的有限数据建议那灌注,损害能甚至在 ischaemia 的短经期以后发生。象糖尿病患者和 arteriopaths 那样的高风险组在特别风险。进一步的研究被需要决定安全止血带时间和压力。 | Brian A Parsons Odunayo Kalejaiye Mustafa Mohammed Raj A Persad | 2013 | Asian Journal of Andrology2013，15，3： | 4 |
| 3 | Angiogenic Remodeling in Pediatric EoE Is Associated With Increased Levels of VEGF-A, Angiogenin, IL-8, and Activation of the TNF-α–NFκB Pathway显示文摘 | Rabindranath Persad Hien Q. Huynh Li Hao Jacqueline R. Ha Consolato Sergi Rahul Srivastava Sujata Persad | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012，，3： | 2 |
| 4 | Determinants of perinatal mortality and serious neonatal morbidity in the second twin 显示文摘 | Armson BA O'Connell C Persad V | 2006 | Obstet Gyneco12006，108，31： | 1 |
| 5 | Clinical Practice Recommendations for the Management of Non-Muscle Invasive Bladder Cancer显示文摘 | Lamm D Colombel M Persad R | 2008 | european urology supplements2008，7，： | 1 |
| 6 | Maternal breastfeeding attitudes : associa- tion with breasffeeding intent and socio-demographics among urban primiparas显示文摘 | Persad MD Mensinger JL | 2008 | J Community Health2008，33，2： | 1 |
| 7 | Colonal analysis of human recurrent superficial bladder cancer by immunohistochemistry of p53 and retinoblastoma proteins显示文摘 | Chern HD Becich MJ Persad RA | 1996 | J Urol1996，156，5： | 1 |
| 8 | Inhibition of integrin-linked kinase(ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of FIZN-mutant prostate cancer cells显示文摘 | Persad S Attwell S Gray V | 2000 | Proc Natl Acad Sei U S A2000，97，7： | 1 |
| 9 | Use of bacilli Calmette-Guerin in superficial bladder cancer显示文摘 | Meyer JP Persad R Gillatt DA | | 0，，922： | 1 |
| 10 | Railgun tribology-chemical reactions be- tween contacts显示文摘 | Chadee Persad | 2007 | IEEE Trans Magn2007，43，1： | 1 |
| 11 | Role of H202 in changing beta-adrenoceptor and adenylyl cyclase in ischmia-reperfused hearts显示文摘 | Dhalla NS | 1998 | Mol Cell Biochem1998，186，： | 1 |
| 12 | Intestinal and gastric permeability in children with eosinophilic esophagitis and reflux esophagitis显示文摘 | Leung AJ Persad S Slae M | 2014 | J Pediatr Gastmenterol Nutr2014，，： | 1 |
| 13 | Regulation of protein kinase B/Akt-Serine-473 phosphorylation by integrin linked kinase (ILK): critical roles for kinase activity and amino acids arginine-211 and serine-343显示文摘 | Persad S Atwell S Gray V | 2001 | J Biol Chem2001，276，27： | 1 |
| 14 | Overexpression of caspase-3 in hepatocellular carcinomas显示文摘 | Persad R Liu C Wu TT | 2004 | Mod Pathol2004，17，7： | 1 |
| 15 | Inhibition of inergrin-linked kinase (ILK)suppresses activation of protein kinase B/AKT and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells显示文摘 | Persad S Attwell S Gray V | | 0，，： | 1 |
| 16 | The role of integrin-linked kinase (ILK) in cancer progression显示文摘 | Persad S Dedhar S | 2003 | Cancer Metastasis Rev2003，22，4： | 1 |
| 17 | Angiogenicremodeling in pediatric eosinophilic esophagitis is associatedwith increased levels of VEGFA,angiogenin,IL-8 andactivation of the TNF-cx-NFkB pathway 显示文摘 | Persad R Huynh HQ Hao L | 2012 | ] PediatrGastroenterol Nutr2012，55，3： | 1 |
| 18 | Inhibition of intergrinlinked kinase (ILK) suppresses activation of protein kinase B/AKT and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells 显示文摘 | Persad S Attwell S Gray V | 2000 | Proc Natl Acad Sci U S A2000，97，7： | 1 |
| 19 | Inhibition of integrin linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN mutant prostate cancer cells显示文摘 | Persad S A ttwell S Gray V | 2000 | Proc Natl Acad Sci USA2000，97，： | 1 |
| 20 | Use of two de-tection methods for discriminating ciguatoxins from brevetoxins:applica-tion to Great Barracuda from Florida显示文摘 | DECHRAOUI M Y B TIEDEKEN J A PERSAD R | 2005 | Toxicon2005，46，： | 1 |
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