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| 1 | 在与心肌的梗塞介绍的就医的病人的心率的预示的意义显示文摘 AIM: To investigate the prognostic significance of resting heart rate in patients with acute coronary syndrome (ACS), independent of other known factors. METHODS: Patients 40 years of age or older who had been admitted with acute coronary syndrome (ACS) to one of the 94 hospitals participating in the Prevalence of Peripheral Arterial Disease in Patients with Acute Coronary Syndrome (PAMISCA) study were included. Patients were divided into two groups based on their resting heart rate (HR ≥ or < 70 bpm). Complications were recording during a follow-up period of 1 year. RESULTS: There were 1054 ACS patients analyzed (43.5% with ST segment elevation and 56.5% without elevation). Mean age was 66.6 ± 11.7 years, 70.6% were male and 29.4% of subjects were female. During follow-up, more patients in the HR ≥ 70 bpm group were hospitalized for heart failure and they also had a higher mortality rate. In the multivariate analysis, a heart rate of ≥ 70 bpm was independently related to overall mortality during the follow-up period (hazard ratio 2.5; 95% confidence interval, 1.26-4.97, P = 0.009). CONCLUSION: A resting heart rate ≥ 70 bpm in patients who survive an ACS is an indicator of a high risk of suffering cardiovascular events during follow-up. | Lorenzo Fácila Pedro Morillas Juan Quiles Federico Soria Alberto Cordero Pilar Mazón Manuel Anguita Cándido Martín-Luengo Jose Ramón Gonzalez-Juanatey Vicente Bertomeu | 2012 | World Journal of Cardiology2012，4，1： | 3 |
| 2 | Genetic variability related to serum uric acid concentration and risk of Parkinson’s disease显示文摘 | Isabel González‐Aramburu Pascual Sánchez‐Juan Silvia Jesús Ana Gorostidi Eduardo Fernández‐Juan Fátima Carrillo María Sierra Pilar Gómez‐Garre María T. Cáceres‐Redondo José Berciano Javier Ruiz‐Martínez Onofre Combarros Pablo Mir Jon Infante | 2013 | Mov Disord2013，，： | 1 |
| 3 | Non-destructive detection of hollow heart in potatoes using hyperspectral imaging显示文摘 | Angel D N Arno F Pilar C | 2011 | Image Analysis and Processing2011，6855，1： | 1 |
| 4 | Determination of total selenium and selenium distribution in the milk phases in commercial cow's milk by HG-AAS显示文摘 | Cocar M N Raquel D G Adela B B Jos6 A C Jos6 M F Pilar B B | 2005 | Analytical and Bioanalytical Chemistry2005，381，6： | 1 |
| 5 | J Chromatogr B显示文摘 | Rosa H H Pilar C F | 2000 | 740:1692000，740，： | 1 |
| 6 | Recovery of gallium and vanadium from gasification fly ash显示文摘 | Oriol F Xavier Q Juan R Casado R Carmen R R (A)ngel L S Pilar C Francisco G P | 2007 | Journal of Hazardous Materials2007，139，4： | 1 |
| 7 | Effect of the Vla/V2- AVP receptor antagonist, conivaptan, on renal water metabolism and systemic hemodynamics in rats with cirrhosis and ascites显示文摘 | Guillermo F Josefa R Pilar C | 2003 | J Hepatol2003，38，3： | 1 |
| 8 | Chromatographic separation of chlothalidone enantiomers using β-cyclodextrins as additives显示文摘 | ROSA H H PILAR C F | 2000 | Journal of Chromatography B2000，740，： | 1 |
| 9 | Common scab deteetion on potatoes using an infrared hyperspectral imaging system 显示文摘 | Angel DN Amo F Pilar C | 2011 | Image Analysis and Processing2011，，6979： | 1 |
| 10 | Chromatographic separation of chlothalidone enantiomers using, cyclodextrins as additives 显示文摘 | Rosa H H Pilar C F | 2000 | J Chromatogr B2000，740，： | 1 |
| 11 | Nested multiplex PCR assay for detection of human enteric viruses in shellfish and sewage显示文摘 | MERITXELL F C AYALKIBET H PILAR C C | 2005 | Journal of Virological Methods2005，125，： | 1 |
| 12 | Chromatographic separation of chlothalidone enantiomers using β - cyclodextrins as additives显示文摘 | Rosa H H Pilar C F | 2000 | J Chromatogr B2000，740，： | 1 |
| 13 | Immobilization of Rhodococcus fasdans cells in poly(vinylaleohol) cryogels for the debittering of citrus juices 显示文摘 | Lopez F M Pilar I M C Martnez M I | 2007 | Journal of Biotechnology2007，，131： | 1 |
| 14 | Oxidantmechanisms in childhood obesity: the link between inflamma-tion and oxidative stress 显示文摘 | PILAR C F VICTORIA V B ANGELA AC | 2011 | Translational Res2011，158，6： | 1 |
| 15 | Coordination as an archi- tectural aspect 显示文摘 | Carlos E C Pilar R M Pablo D F | 2006 | Electronic Notes in Theoretical Computer Science2006，154，1： | 1 |
| 16 | Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents:EPIC05-Sierra75 study显示文摘OBJECTIVES Elderly patients show a higher incidence of ischemic and bleeding events after percutaneous transluminal coron-ary intervention(PCI).We sought to investigate outcomes in elderly patients treated with antithrombotic strategy guided by bleeding and ischemic risks after revascularization with last generation everolimus-eluting stent(EES).METHODS Prospective multicenter registry including patients over 75 years revascularized with EES and antithrombotic ther-apy guided by clinical presentation,PCI complexity and PRECISE DAPT score.Co-primary safety endpoints were:(1)composite of cardiac death,myocardial infarction and stent thrombosis and;(2)bleeding(BARC 2-5).Primary efficacy endpoint was target lesion revascularization.A matched group of patients revascularized with current drug-eluting stents and no such tailored antith-rombotic therapy was used as control.RESULTS Finally,1064 patients were included in SIERRA-75 cohort,80.8±4.2 years,36.6%women,71%acute coronary syn-dromes(ACS)and 53.6%complex PCI.Co-primary safety endpoint of major adverse cardiovascular events was met in 6.2%,co-primary safety endpoint of bleeding in 7.8%and primary efficacy endpoint of TKLR in 1.5%.The multivariable adjusted model showed no significant association of the prescribed short/long dual antiplatelet therapy(DAPT)durations with any endpoint suggesting a well tailored therapy.No stent thrombosis reported in the subgroup with 1-3 months DAPT duration.As compared to control group,bleeding BARC 2-5 was significantly lower in SIERRA-75 group(7.4%vs.10.2%,P=0.04)as well as the net safety-efficacy endpoint(14.3%vs.18.5%,P=0.02).CONCLUSIONS In elderly population,the application of this risks-adjusted antithrombotic protocol after revascularization with last generation EES seems to be associated with an improved prognosis in terms of ischemic and bleeding outcomes. | Jose M de la Torre Hernandez Ramon Lopez Palop Jesus M Jimenez Mazuecos Pilar Carrillo Sáez Alejandro Gutierez-Barrios Eduardo Pinar Belen Cid Luis Fernandez Tamara Garcia Camarero Cristóbal Urbano-Carrillo Juan F Oteo Dominguez Victor A Jimenez Diaz Antonio EGomez Menchero Eladio Galindo Fernández Juan GCórdoba Soriano Raymundo Ocaranza Eduardo ArroyoÚcar Koldobika Garcia San Roman Silvio Leal Ginés Martínez Cáceres Jose A Linares Vicente Georgina Fuertes Ferre Xavier Carrillo Juan CRama Merchán Catia Costa Juan Sanchis Renato Fernandes Alberto Rodrigues Jose M Vegas Valle Hélder Pereira Armando Perez de Prado | 2022 | Journal of Geriatric Cardiology2022，19，5： | 0 |
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