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| 1 | Clinical implications of diabetes in chronic liver disease:Diagnosis,outcomes and management,current and future perspectives显示文摘Diabetes mellitus(DM)is common in liver cirrhosis(LC).The pathophysiological association is bidirectional.DM is a risk factor of LC and LC is a diabetogenic condition.In the recent years,research on different aspects of the association DM and LC has been intensified.Nevertheless,it has been insufficient and still exist many gaps.The aims of this review are:(1)To discuss the latest understandings of the association of DM and LC in order to identify the strategies of early diagnosis;(2)To evaluate the impact of DM on outcomes of LC patients;and(3)To select the most adequate management benefiting the two conditions.Literature searches were conducted using Pub Med,Ovid and Scopus engines for DM and LC,diagnosis,outcomes and management.The authors also provided insight from their own published experience.Based on the published studies,two types of DM associated with LC have emerged:Type 2 DM(T2 DM)and hepatogenous diabetes(HD).High-quality evidences have determined that T2 DM or HD significantly increase complications and death pre and post-liver transplantation.HD has been poorly studied and has not been recognized as a complication of LC.The management of DM in LC patients continues to be difficult and should be based on drug pharmacokinetics and the degree of liver failure.In conclusion,the clinical impact of DM in outcomes of LC patients has been the most studied item recently.Nevertheless many gaps still exist particularly in the management.These most important gaps were highlighted in order to propose future lines for research. | Diego García-Compeán Emanuela Orsi Ramesh Kumar Felix Gundling Tsutomu Nishida Jesús Zacarías Villarreal-Pérez Ángel N Del Cueto-Aguilera JoséA González-González Giuseppe Pugliese | 2022 | World Journal of Gastroenterology2022，28，8： | 4 |
| 2 | A review of HIV-1 Tat protein biological effects 显示文摘 | Pugliese A Vidotto V Beltramo T | 2005 | Cell Biochem Funct2005，23，4： | 1 |
| 3 | Compression waves generated in rock by cylindrical explosive chages: A compression between a computer model and field measurement显示文摘 | Starfield A M Pugliese J M | 1968 | Int J of Rock Mech and Min Sci1968，，5： | 1 |
| 4 | The Chronic Kidney Disease Epidemiology Collaboration ( CKD- EPI ) e- quation provides a better definition of cardiovascular burden associated with CKD than the Modification of Diet in Renal Disease( MDRD)Study formula in subjects with type 2 dia- betes显示文摘 | PUGLIESE G SOLINI A BONORA E | 2011 | Atherosclerosis2011，218，1： | 1 |
| 5 | A calculus fororchestration of web services显示文摘 | LAPAFULA A PUGLIESE R TIEZZI F | 2007 | Lecture Notes in ComputerScience2007，4421，： | 1 |
| 6 | Interaction of human plasma fibronectin with viral proteins of human immunodeficiency virus显示文摘 | Torre D Pugliese A Ferrario G | 1994 | FEMS Immunol Med Microbiol1994，8，2： | 1 |
| 7 | COWS:a timedservice-oriented calculus显示文摘 | LAPADULA A PUGLIESE R TIEZZI F | 2007 | Lecture Notes in Computer Sci-ence2007，4711，： | 1 |
| 8 | E 6 ]- Gingerol suppresses colon cancer growth by targeting leukotriene A4 hydrolase 显示文摘 | JEONG C H BODE A M PUGLIESE A | 2009 | Cancer Res2009，69，13： | 1 |
| 9 | The chronic kidney disease ep- idemiology collaboration ( CKD - EPI) equation provides a better defi- nition of cardiovascular burden associated with CKD than the modifi- cation of diet in renal disease (MDRD) study formula in subjects with type 2 diabetes 显示文摘 | Pugliese G Solini A Bonora E | 2011 | Atherosclerosis2011，218，： | 1 |
| 10 | Service discover-y and negotiation with COWS显示文摘 | LAIjADULA A PUGLIESE R TIEZZI F | 2008 | Electronic Notes in Theo-retical Computer Science2008，200，3： | 1 |
| 11 | Phagocytic activity in human immunodeficiency virus type 1 infection显示文摘 | Pugliese A Vidotto V Beltramo T | 2005 | Clin and Diag Lab Immuno2005，12，8： | 1 |
| 12 | Phagocytic activity in human immunodeficiency virus type 1 infection显示文摘 | Pugliese A Vidotto V Beltramo T | 2005 | Clin Diagn Lab Immunol2005，12，8： | 1 |
| 13 | Compression waves generated in rock by ccylindrical explosive charges: A comparison between a computer model and field measurement 显示文摘 | Pugliese J M | 1968 | Int J Rock Mech Min Sci1968，5，： | 1 |
| 14 | Modeling and supporting grid scheduling显示文摘 | Pugliese A Talia D Yahyapour R | 2008 | J Grid Computing2008，，6： | 1 |
| 15 | The effect of domes- tic processing on the content and bioaccessibility of carotenoids from chili peppers (Capsicum species) 显示文摘 | Pugliese A Loizzo M R Tundis R | 2013 | Food Chemistry2013，141，3： | 1 |
| 16 | Update on the management of inflammatory bowel disease:specific role of adalimumab 显示文摘 | Guidi L Pugliese D Armuzzi A | 2011 | Clin Exp Gastroentero12011，4，： | 1 |
| 17 | Inhibition of Fas-mediated apoptosis in mouse insulinoma betaTC-3 cells via an anti-Fas ribozyme显示文摘 | Ricordi C Pugliese A | 2000 | Hum Gene Ther2000，11，7： | 1 |
| 18 | Lichen sclerosus:review of the literature and current recommendations for management显示文摘 | Pugliese J M Morey A F Peterson A C | 2007 | J Urol2007，178，6： | 1 |
| 19 | Serum citrate levels,haptoglotypes and transferring receptor(CD71 ) in patients with HIV-1 inefction显示文摘 | Pugliese A Gennero L Pescarmona GP | 2002 | Infection2002，30，2： | 1 |
| 20 | Phagocytic activity in human immunodeficiency virus type 1 infection显示文摘 | Pugliese A Vidotto V Beltramo T | 2005 | Clin Diag Lab Immunol2005，12，8： | 1 |
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