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86篇 您的检索式：作者名="Pabla"

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	题名	作者	年代	出处	被引量
1	Colon cancer and the epidermal growth factor receptor:Current treatment paradigms,the importance of diet,and the role of chemoprevention显示文摘Colorectal cancer represents the third most common and the second deadliest type of cancer for both men and women in the United States claiming over 50000 lives in 2014. The 5-year survival rate for patients diagnosed with metastatic colon and rectal cancer is < 15%. Early detection and more effective treatments are urgently needed to reduce morbidity and mortality of patients afflicted with this disease. Here we will review the risk factors and current treatment paradigms for colorectal cancer, with an emphasis on the role of chemoprevention as they relate to epidermal growth factor receptor(EGFR) blockade. We will discuss how various EGFR ligands are upregulated in the presence of Western diets high in saturated and N-6 polyunsaturated fats. We will also outline the various mechanisms of EGFR inhibition that are induced by naturally occurring chemopreventative agents such as ginseng, green tea, and curcumin. Finally, we will discuss the current role of targeted chemotherapy in colon cancer and outline the limitations of our current treatment options, describing mechanisms of resistance and escape.	Baldeep Pabla Marc Bissonnette Vani J Konda	2015	World Journal of Clinical Oncology2015，6，5：	7
2	Effects of NO modulation on cardiac arrhythmias in the rat isolated heart显示文摘	Pabla R Curtis MJ	1995	Circ Res1995，77，5：	1
3	Nitric oxide attenuates neutropphil-mediated myocardial contractile dysfunction after ischemia and reperfusion显示文摘	Pabla R Buad AJ Flynn DM	1996	Circ Res1996，78，1：	1
4	A comparative pHdissolution profile study of selected commercial levothyroxine products using inductively coupled plasma mass spectrometry显示文摘	Pabla D Akhlaghi F Zia H	2009	Eur J Pharm Biopharm2009，72，：	1
5	PKC-delta promotes re- nal tubular cell apoptosis associated with proteinuria 显示文摘	Li X Pabla N Wei Q	2010	J Am Soc Nephrol2010，21，：	1
6	The copper transporter Ctrl contributes to cisplatin uptake by re- nal tubular cells during cisplatin nephrotoxicity 显示文摘	Pabla N Murphy RF Liu K	2009	Am J Physiol Renal Physiol2009，296，3：	1
7	Effects of NO modulation on cardiac arrhythmias in the rat isolated heart显示文摘	Pabla R Curtis MJ	1995	Circ Res1995，77，5：	1
8	Nitric oxide attenuates neutrophil-mediated myocardial contractile dysfunction after ischemia and reperfusion显示文摘	Pabla RP Buola A T Flymn DM	1996	Circ Res1996，78，：	1
9	Cisplatin nephrotoxicity : mechanisms andrenoprotective strategies 显示文摘	Pabla N Dong Z	2008	Kidney Int2008，73，9：	1
10	ATR-Chk2 signaling inp53activation and DNA damage response during cisplatin-inducedapoptosis 显示文摘	Pabla N Huang S Mi QS	2008	J Biol Chem2008，283，10：	1
11	Effect of Endogenous Nitric Oxide on Cardiac Systolic and Diastolic Function During Ischemia and Reperfusion in the Rat Isolated Perfused Heart显示文摘	Ravinder Pabla Michael J. Curtis	1996	Journal of Molecular and Cellular Cardiology1996，，10：	1
12	Checkpoint kinase 1 (Chkl) - short is a splice variant and endogenous inhibitor of Chkl that regulates cell cycle and DNA damage checkpoints 显示文摘	Pabla N Bhatt K Dong Z	2012	Proc Natl Acad Sci USA2012，109，1：	1
13	Cisplatin nephrotoxicity:mechanisms and renoprotective strategies显示文摘	PABLA N DONG Z		0，，09：	1
14	Effects of NO modulgion on cardiac ar- rhythmias in the rat isolated hear显示文摘	Pabla R Curtis MJ	1995	Circ Res1995，77，5：	1
15	Effect of endogenous nitric oxide on cardiac systolic and diastolic function during ischemia and reperfusion in the rat isolated perfused heart显示文摘	PABLA R CURTIS MJ	1996	J Mol Cell Cardial1996，28，10：	1
16	Nitric oxide attenuates neutrophil-mediated显示文摘	Pabla R Buda AJ Flynn DM	1996	Cir Res1996，78，：	1
17	Cisplatin nephrotoxicity:mechanisras and renopro- tective strategies 显示文摘	Pabla N Dong Z	2008	Kidney Int2008，73，9：	1
18	Nitric oxide attenuates neutrophil-mediated myocardial contractile dysfunction after ischemia and reperfusion显示文摘	Pabla R Buda A J Flynn D M	1996	Circ Res1996，78，1：	1
19	Effect of endogenous nitric oxide on cardiac systolicand diastolic function during ischemia and reperfusion in the rat isolatedperfused heart显示文摘	Pabla R Curtis MJ	1996	J Mol Cell Cardial1996，28，10：	1
20	PKC-delta promotes renal tubular cell apoptosis assosicated with proteinuria显示文摘	Li X Pabla N Wei Q	2010	J Am Soc Nephrol2010，21，7：	1

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