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| 1 | Characterization of entertoxigenic Escherichia coli by random amplication of polymorphic DNA 显示文摘 | A B F Pacheco B E C Guth D F | 1996 | Res Microbiol1996，，147： | 1 |
| 2 | Ability of commercially available dairy ration programs to predict duodenal flows of protein and essential amino acids in dairy cows显示文摘 | PACHECO D PATTON R A PARYS C | 2012 | Journal of Dairy Science2012，95，2： | 1 |
| 3 | Social diversity promotes the emergence of cooperation in public goods games显示文摘 | Santos F C Santos M D Pacheco J M | 2008 | Nature2008，454，7201： | 1 |
| 4 | Lentiviral vectors pseudotyped with baculovirus gp64 efficiently transduce mouse cells in vivo and show tropism restriction against hematopoietic cell types in vitro 显示文摘 | Schauber C A Tuerk M J Pacheco C D | 2004 | Gene Ther2004，11，3： | 1 |
| 5 | Analysis of neu- tral nitrogen compounds in diesel oil by direct injection high- performance liquid chromatography-mass spectrometry ultra- violet spectrometry methods显示文摘 | Mao J Pacheco C R Traficante D D | 1994 | J Chromatogr A1994，684，1： | 1 |
| 6 | Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line 显示文摘 | Hughes E D Qu Y Y Genik S J Lyons R H Pacheco C D Lieberman A P | 2007 | Mamm Genome2007，18，： | 1 |
| 7 | Angioten- sin Ⅱ signaling increases activity of the renal Na - C1 cotransporter through a WNK4 - SPAK - dependent pathway 显示文摘 | San - Cristobal P Pacheco - Alvarez D Richardson C | 2009 | Proc Natl Acad Sci USA2009，106，11： | 1 |
| 8 | Ability of commercially available dairy ration programs to predict duodenal flows of protein and essential amino acids in dairy cows显示文摘 | PACHECO D PATTON R A PARYS C | 2012 | Journal of Dairy Science2012，95，2： | 1 |
| 9 | Social diversity promotes the emergence of cooperation in public goods games显示文摘 | SANTOS M D PACHECO J M | 2008 | Nature2008，，454： | 1 |
| 10 | Social diversity pro- motes the emergence of cooperation in public goods games 显示文摘 | Santos F C Santos M D Pacheco J M | 2008 | Nature2008，454，： | 1 |
| 11 | Lentiviral vectors pseudotyped with baculovirus gp64 efficiently transduce mouse cells in vivo and show tropism restriction against hematopoietic cell types in vitro 显示文摘 | Schauber C A Tuerk M J Pacheco C D | 2004 | Gene Ther2004，11，3： | 1 |
| 12 | Social diversity promotes the emergence of cooperation in public goods games 显示文摘 | Santos F C Santos M D Pacheco J M | 2008 | Nature2008，454，7201： | 1 |
| 13 | Active tuberculosis in inflammatory bowel disease patients under treatment from an endemic area in Latin America显示文摘BACKGROUND There has been an increase in cases of inflammatory bowel disease(IBD)in recent years.There is also greater access and availability of immunosuppressive and biological agents,which increase the risk of opportunistic infection despite improving the quality of life and promoting mucosal healing.Tuberculosis(TB)remains a public health problem,and it has a high incidence in several countries.Therefore,knowledge of the risk of developing TB in patients with IBD is important.AIM To evaluate the risk of active TB in patients with IBD under treatment from an endemic area in Latin America.METHODS A standard questionnaire included demographic variables,clinical aspects of IBD disease,history of active TB during treatment,active TB characteristics and evolution,initial screening and results and time from the start of anti-tumor necrosis factor alpha(TNFα)to TB development.RESULTS Azathioprine,anti-TNFα and the combination of these two drugs were associated with a higher risk of active TB incidence.The TNFα blockers increased the relative risk of developing active TB compared to other treatments.All four multivariable models showed that the use of TNFα blockers alone or in combination with azathioprine was an important risk factor for the incidence of active TB.After adjustment for sex,age,type of IBD and latent TB,anti-TNFα with azathioprine increased the relative risk to 17.8 times more than conventional treatment.Late TB,which was diagnosed 3 mo after the start of anti-TNFα,was the most frequent.CONCLUSION Treatment with anti-TNFα increased the risk of active TB in IBD patients from an endemic area in Latin America.This risk was increased when anti-TNFα was combined with azathioprine.The time from the beginning of the treatment to the active TB diagnosis suggests a new TB infection. | Flora Maria Lorenzo Fortes Ney Boa Sorte Victor D Mariano Laila D Andrade Fernanda A Oliveira Monique CA Santos Claudia Ivanilda N dos Santos Catharina A Passos Mila P Pacheco Valdiana C Surlo Neogelia P de Almeida Jaciane AM Fontes Andrea M Pimentel Raquel Rocha Genoile Oliveira Santana | 2020 | World Journal of Gastroenterology2020，26，44： | 1 |
| 14 | Identification and Characterization of Nitrogen Compounds in Brazilian Diesel oil by Particle Beam LC-MS显示文摘 | Mao J Pacheco C R Traficante D D | 1995 | Fuel1995，74，6： | 1 |
| 15 | Social diversity promotes the emergence of cooperation in public goods games显示文摘 | SANTOS F C SANTOS M D PACHECO J M | | 0，，7201： | 1 |
| 16 | Highly Active Oxime-Derived Palladacycle Complexes for Suzuki-Miyaura and Ullmann-Type Coupling Reactions 显示文摘 | ALONSO D A N?JERA C PACHECO M C | 2002 | Journal of Organic Chemistry2002，67，： | 1 |
| 17 | Highly active oxime- derived palladacycle complexes for Suzuki-Miyaura and Ullmann-Type coupling reactions 显示文摘 | Alonso D A Najera C Pacheco M C | 2002 | Journal of Organic Chemistry2002，67，16： | 1 |
| 18 | Selenium levels in mailand portugal显示文摘 | Ventural M A Freitas M D C Pacheco A M G | 2005 | Water Air Soil Pollut2005，166，： | 1 |
| 19 | Essential hyper- tension is associated wit h decreased insulin clearance and insulin resistance显示文摘 | Lender D Arauz Pacheco C Adams Huet B | 1997 | Hypertension1997，29，： | 1 |
| 20 | Social diversity promotes the emergence of cooperation in public goods games显示文摘 | Santos F C Santos M D Pacheco J M | 2008 | Nature2008，454，7201： | 1 |
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