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| 1 | Collagen type Ⅳ promotes the differentiation of neuronal progenitors and inhits astroglial differentiation in Cortical cell cultures 显示文摘 | Pappas IS Parnsavelas JG | 1998 | Brain Res Dev1998，110，1： | 1 |
| 2 | Basic fibroblast growth factor promotes the generation and differentiation of calretinin neurons in the rat cerebral cortex in vitro 显示文摘 | Pappas IS Parnavelas JG | 1998 | Eur J Neurosci1998，10，4： | 1 |
| 3 | Collagen type IV promotes the differentiation of neuronal progenitors and inhibits astroglial differen- tiation in cortical cell cultures显示文摘 | Ali SA Pappas IS Pamavelas JG | 1998 | Dev Brain Res1998，1，： | 1 |
| 4 | Mechanismsinvolved in the induced d if e r e n /a /o n of leukem ia cells显示文摘 | Tsiftsoglou A S Pappas IS Vizirianakis IS | | Pharmacol They0，100，3： | 1 |
| 5 | Collagen type Ⅳ promotes the differentiation of neuronal progenitors and inhibits astroglial differentiation in cortical cell cultures显示文摘 | Ali SA Pappas IS Parnavelas JG | 1998 | Brain Res Dev Brain Res1998，110，1： | 1 |
| 6 | Neurotrophins and basic fibroblast growth factor induce the differentiation of calbindin-containing neurons in the cerebral cortex显示文摘 | Pappas IS Parnavelas JG | 1997 | Exp Neurol1997，144，： | 1 |
| 7 | Basic fibroblast growth factor prolongs the proliferation of rat cortical progenitor cells in vitro without altering their cell cycle parameters显示文摘 | Cavanagh JF Mione MC Pappas IS | 1997 | Cereb Cortex1997，7，4： | 1 |
| 8 | Serotonin promotes the survival of cortical glutamatergic neurons in vitro显示文摘 | Dooley AE Pappas IS Pamavelas JG | 1997 | Exp Neurol1997，148，： | 1 |
| 9 | Basic fibroblast growth factor prolongs the proliferation of rat cortical progenitor cells in vitro without altering their cell cycle parameters显示文摘 | Cavanagh JF Mione MC Pappas IS | 1997 | Cereb Cortex1997，7，4： | 1 |
| 10 | Basic fibroblast growth factor prolongs the proliferation of rat cortical progenitor cells in vitro without altering their cell cycle parameters 显示文摘 | Cavanagh JF Mione MC Pappas IS | 1997 | Cereb Cortex1997，7，4： | 1 |
| 11 | Mechanisms in- volved in tile induced differentiation of leukemia cells 显示文摘 | Tsiftsoglou AS Pappas IS Vizirianakis IS | 2003 | Pharmacol Ther2003，100，： | 1 |
| 12 | Mechanisms involved in the induced differentiation of leukemia cells 显示文摘 | Tsiftsoglon AS Pappas IS Vizirianakis IS | 2003 | Phannacol Ther2003，100，3： | 1 |
| 13 | Organic transistor platform with integrated microfluidics for in-line multi-parametric in vitro cell monitoring显示文摘Future drug discovery and toxicology testing could benefit significantly from more predictive and multi-parametric readouts from in vitro models.Despite the recent advances in the field of microfluidics,and more recently organ-on-a-chip technology,there is still a high demand for real-time monitoring systems that can be readily embedded with microfluidics.In addition,multi-parametric monitoring is essential to improve the predictive quality of the data used to inform clinical studies that follow.Here we present a microfluidic platform integrated with in-line electronic sensors based on the organic electrochemical transistor.Our goals are twofold,first to generate a platform to host cells in a more physiologically relevant environment(using physiologically relevant fluid shear stress(FSS))and second to show efficient integration of multiple different methods for assessing cell morphology,differentiation,and integrity.These include optical imaging,impedance monitoring,metabolite sensing,and a wound-healing assay.We illustrate the versatility of this multi-parametric monitoring in giving us increased confidence to validate the improved differentiation of cells toward a physiological profile under FSS,thus yielding more accurate data when used to assess the effect of drugs or toxins.Overall,this platform will enable high-content screening for in vitro drug discovery and toxicology testing and bridges the existing gap in the integration of in-line sensors in microfluidic devices. | Vincenzo F.Curto Bastien Marchiori Adel Hama Anna-Maria Pappa Magali P.Ferro Marcel Braendlein Jonathan Rivnay Michel Fiocchi George G.Malliaras Marc Ramuz Róisín M.Owens | 2017 | Microsystems & Nanoengineering2017，3，1： | 0 |
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