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| 1 | Aerobic bacterial flora of the normal conjunctiva at high altitude area of Shimla Hills in India:a hospital based study显示文摘AIM:To study the normal aerobic conjunctival flora in lower to mid Himalayan region of Shimla Hills.METHODS:Samples from normal conjunctiva of 200 individuals above the age of 13 years who visited Indira Gandhi Medical College Hospital Shimla for refraction or cataract surgery were taken by anaesthetising the conjunctival sac with sterile 4% Xylocaine solution.Samples were obtained by gently rubbing lower fornix with a sterile cotton wool swab moistened with normal saline and keeping the eye lids wide apart to avoid contamination from lid margins.It was immediately inoculated in Brain Heart infusion and subjected to standard aerobic culture and identification techniques.RESULTS:Totally,72 eyes(36%) conjunctival sacs were sterile.Predominant aerobes isolated were Staphylococcus spp.in 120(60%) followed by Haemophilus in 16(8%),diphtheroids in 10(5%),and Escherichia coli(E.coli) in 4(2%).A single aerobe was isolated from 98 eyes(49%) while 30 eyes(15%) yielded more than 1 aerobe.Staphylococcus epidermidis(S.epidermidis) was the most common bacterium,found alone in 58 eyes(29%) and in combination with another aerobe in 30 eyes(15%),followed by Staphylococcus aureus(S.aureus) in 18(9%) and 10 eyes(5%) respectively.CONCLUSION:S.epidermidis is the most common commensal organism followed by Haemophilus species.diphtheroids occupied the third position which otherwise are found more abundantly in literature.Pathogens like S.aureus,Staphylococcus citreus and E.coli were also found.Therefore,preoperative administration of topical broad spectrum antibiotics is extremely important in prophylaxis against ocular infection.The variation in microflora of normal conjunctiva in this part of world can be attributed to geographical,climatic and ethnic characteristics of the population under study. | Sharma Parmeshri Dass Sharma Neelam Gupta Ravinder Kumar Singh Parul | 2013 | International Journal of Ophthalmology(English edition)2013，6，5： | 4 |
| 2 | Correlation of Frequency-doubling Perimetry With Retinal Nerve Fiber Layer Thickness and Optic Disc Size in Ocular Hypertensives and Glaucoma Suspects显示文摘 | Sushmita Kaushik Surinder Singh Pandav Parul Ichhpujani Amod Gupta | 2011 | Journal of Glaucoma2011，，6： | 1 |
| 3 | Determination of ultratrace selenium and arsenic at parts-per-trillion levels in environmental and biological samples by atomic fluorescence spectrometry with flow injection hydride generation technique显示文摘 | Lei Wei Parul Gupta Robert Hernandez | 1999 | Microchemical Journal1999，62，： | 1 |
| 4 | Ocular chemical injuries and their management显示文摘 | Parul Singh Manoj Tyagi Yogesh Kumar K Gupta P Sharma | 2013 | Oman Journal of Ophthalmology2013，，2： | 1 |
| 5 | Software Radio: A Review of Design Considerations and Digital Hardware Choices显示文摘This paper reviews the requirements for Software Defi ned Radio (SDR) systems for high-speed wireless applications and compares how well the different technology choices available-from ASICs, FPGAs to digital signal processors (DSPs) and general purpose processors (GPPs) - meet them. | Parul Gupta Pradipta Dey Shivkumar Kalyanaraman Wang Qing Chen Jianwen Lin YongHua | 2009 | China Communications2009，6，1： | 1 |
| 6 | Ocular chemical injuries and their management显示文摘 | Parul Singh Manoj Tyagi Yogesh Kumar K Gupta P Sharma | 2013 | Oman Journal of Ophthalmology2013，，2： | 1 |
| 7 | Pathways of nanotoxicity:Modes of detection,impact,and challenges显示文摘Nanotoxicology has become the subject of intense research for more than two decades.Thousands of articles have been published but the space in understanding the nanotoxicity mechanism and the assessment is still unclear.Recent researches clearly show potential benefits of nanomaterials(NMs)in diagnostics and treatment,targeted drug delivery,and tissue engineering owing to their excellent physicochemical properties.However,these NMs display hazardous health effect then to the greater part of the materials because of small size,large surface area-to-volume ratio,quantum size effects,and environmental factors.Nowadays,a large number of NMs are used in industrial products including several medical applications,consumer,and healthcare products.However,they came into the environment without any safety test.The measurement of toxicity level has become important because of increasing toxic effects on living organisms.New realistic mechanism-based strategies are still needed to determine the toxic effects of NMs.For the assessment of NMs toxicity,reliable and standardized procedures are necessary.This review article provides systematic studies on toxicity of NMs involving manufacturing,environmental factors,eco-toxic and genotoxic effects,some parameters which have been ignored of NMs versus their biological counterparts,cell heterogeneity,and their current challenges and future perspectives. | Deepshikha GUPTA Parul YADAV Devesh GARG Tejendra K.GUPTA | 2021 | Frontiers of Materials Science2021，15，4： | 0 |
| 8 | Current and New Drugs for COVID-19 Treatment and Its Effects on the Liver显示文摘Corona virus disease(COVID)-19 is caused by the novel severe acute respiratory syndrome coronavirus-2(commonly referred to as SARS-CoV-2).In March 2020,the World Health Organization declared the COVID-19 outbreak a pandemic.Though the target organ for the virus is primarily the lungs,with the recent understanding of the pathobiology of this disease and the immune dysregulation associated with it,it is now clear that COVID-19 affects multiple organ systems.Several drugs and therapies have been tried or repurposed to combat the wrath posed by this disease.On October 22,2020,the USA Food and Drug Administration approved remdesivir for use in adults and pediatric patients(12 years of age and older).Several of the drugs being tried against COVID-19 have hepatotoxicity as their potential side effect.This review aims to provide the latest insights on various drugs being used in the treatment of COVID-19 and their effects on the liver. | Sandeep Satsangi Nitin Gupta Parul Kodan | 2021 | Journal of Clinical and Translational Hepatology2021，9，3： | 0 |
| 9 | Diabetes is affecting everyone everywhere显示文摘The article titled“Accessibility and Utilization of Healthcare Services Among Diabetic Patients:Is Diabetes a Poor Man’s Ailment?”gave insights into a pandemic systemic disease known as diabetes mellitus.This modern-era pandemic affects everyone,regardless of their financial background.As a result,diabetes is not a systemic disease which just involves people of low socioeconomic status. | Parul Chawla Gupta Mona Duggal Arvind Kumar Morya | 2024 | World Journal of Diabetes2024，15，2： | 0 |
| 10 | Co-positivity of anti-dengue virus and anti-Japanese encephalitis virus IgM in endemic area:co-infection or cross reactivity?显示文摘Objective:To report high co-positivity of anti-dengue virus(DV)and anti-Japanese encephalitis virus(JEV)IgM in an area endemic for both the viruses and to discuss the possibilities of coinfection.Methods:Serum samples from the patients who presented with fever,suspected central nervous system infection and thrombocytopenia,were tested for anti-DV IgM and antiJEV IgM antibodies.Conventional reverse transcriptase polymerase chain reaction was done for detection of DV RNA and JEV RNA.Results:Of 1 410 patient sera tested for anti-DV and antiJEV antibodies,129(9.14%)were co-positive for both.This co-positivity was observed only in those months when anli-JEV IgM positivily was high.Tilers of both anli-DV IgM and anti-JEV IgM were high in most of the co-positive eases.Among these 129 co-positive cases,76 were lesled by conventional reverse Iranscriplase polymerase chain reaction for both flaviviruses,of which eight cases were co-positive for DV and JEV.Conclusions:Co-infection with more than one fluvivirus species can occur in hyperendemic areas. | Kaleshwar Prasad Singh Gitika Mishra Parul Jain Nidhi Pandey Rachna Nagar Shikha Gupta Shantanu Prakash Om Prakash Danish Nasar Khan Sakshi Shrivastav Desh Deepak Singh Amita Jain | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，2： | 0 |
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