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| 1 | Biological response to prosthetic debris显示文摘Joint arthroplasty had revolutionized the outcome of orthopaedic surgery. Extensive and collaborative work of many innovator surgeons had led to the development of durable bearing surfaces, yet no single material is considered absolutely perfect. Generation of wear debris from any part of the prosthesis is unavoidable. Implant loosening secondary to osteolysis is the most common mode of failure of arthroplasty. Osteolysis is the resultant of complex contribution of the generated wear debris and the mechanical instability of the prosthetic components. Roughly speaking, all orthopedic biomaterials may induce a universal biologic hostresponse to generated wear débris with little specific characteristics for each material; but some debris has been shown to be more cytotoxic than others. Prosthetic wear debris induces an extensive biological cascade of adverse cellular responses, where macrophages are the main cellular type involved in this hostile inflammatory process. Macrophages cause osteolysis indirectly by releasing numerous chemotactic inflammatory mediators, and directly by resorbing bone with their membrane microstructures. The bio-reactivity of wear particles depends on two major elements: particle characteristics(size, concentration and composition) and host characteristics. While any particle type may enhance hostile cellular reaction, cytological examination demonstrated that more than 70% of the debris burden is constituted of polyethylene particles. Comprehensive understanding of the intricate process of osteolysis is of utmost importance for future development of therapeutic modalities that may delay or prevent the disease progression. | Diana Bitar Javad Parvizi | 2015 | World Journal of Orthopedics2015，6，2： | 16 |
| 2 | 石蜡相变材料作42CrMo4钢的热处理淬火介质显示文摘采用石蜡相变材料作为42CrMo4合金热处理的淬火介质,并与用水、空气和CuO掺杂石蜡作淬火介质进行比较。根据ASTME8M?98标准制备拉伸试样,将试样在电阻炉中加热至830°C,然后保温4 h,再在上述介质中淬火。根据得到的应力?应变曲线确定弹性模量、屈服强度、极限抗拉强度、伸长率和韧性模量。此外,还研究了不同介质热处理后的硬度和显微组织演化。石蜡与CuO掺杂石蜡淬火样品的极限抗拉强度(分别为1439和1306 MPa)高于在水(1190 MPa)和空气(1010 MPa)中淬火样品的。CuO掺杂石蜡淬火样品的硬度最高,为HV552。显微组织研究表明,非淬火钢具有铁素体/珠光体组织,而在水、石蜡和CuO掺杂石蜡中淬火,可获得铁素体/马氏体组织;还观察到,以空气为淬火介质,形成贝氏体/马氏体/铁素体三相组织。 | Milad SAKKAKI Farhad SADEGH MOGHANLOU Soroush PARVIZI Haniyeh BAGHBANIJAVID Aziz BABAPOOR Mehdi SHAHEDI ASL | 2020 | Journal of Central South University2020，27，3： | 3 |
| 3 | Cytokine gene expression in splenic CD4 + and CD8 + T cell subsets of genetically resistant and susceptible chickens infected with Marek’s disease virus显示文摘 | P. Parvizi L.R. Read M.F. Abdul-Careem A.J. Sarson C. Lusty M. Lambourne N. Thanthrige-Don S.C. Burgess S. Sharif | 2009 | Veterinary Immunology and Immunopathology2009，，2： | 2 |
| 4 | Infection Burden for Hip and Knee Arthroplasty in the United States显示文摘 | Steven M. Kurtz Edmund Lau Jordana Schmier Kevin L. Ong Ke Zhao Javad Parvizi | 2008 | The Journal of Arthroplasty2008，，7： | 2 |
| 5 | Cytokine gene expression patterns associated with immunization against Mareks disease in chickens 显示文摘 | ABDUL-CAREEM M F HUNTER B D PARVIZI P | 2007 | Vaccine2007，25，3： | 1 |
| 6 | Pathological laughter and crying in patients with multiple system atrophy-cerebellar type 显示文摘 | Parvizi J Joseph J Press DZ | 2007 | Mov Disord2007，22，6： | 1 |
| 7 | What′s new in total hip arthroplasty显示文摘 | Huo MH Parvizi J Bal BS | 2009 | J Bone Joint Surg2009，91，10： | 1 |
| 8 | Transcriptional analysis of host responses to Marek's disease virus infection in genetically resistant and susceptible chickens 显示文摘 | Sarson A J Parvizi P | 2008 | Anim Gen2008，39，： | 1 |
| 9 | Total hip arthroplas- ty in patients with dwarfism显示文摘 | Chiavetta JB Parvizi J Shaughnessy WJ | 2004 | J Bone Joint Surg Am2004，2，： | 1 |
| 10 | The effect of tibial polyethylene insert design on range of motion:evaluation of in vivo knee kinematics by a computerized navigation system during total knee arthroplasty显示文摘 | Klein G R Parvizi J Papuri V R | 2004 | J Arthroplasty2004，19，8： | 1 |
| 11 | New definition for peripros- thetic joint infection : from the Workgroup of the Musculoskeletal Infec- tion Society显示文摘 | Parvizi J Zmistowski B Berbari EF | 2011 | Clin Orthop Relat Res2011，469，11： | 1 |
| 12 | Novel developments in the prevention, diagnosis, and treatment of periprosthetie joint infections显示文摘 | Parvizi J Alijanipour P Barberi EF | 2015 | J Am Acad Orthop Surg2015，23，： | 1 |
| 13 | The effect of tibial polyethylene insert design on range of motion:evaluation of in vivo knee kinematics by a computerized navigation system during total knee arthroplasty显示文摘 | Klein GR Parvizi J Rapuri VR | | 0，，： | 1 |
| 14 | Nitric oxide and the control of reproduction 显示文摘 | Dixit V D Parvizi N | 2001 | Anita Reprod Sci2001，65，12： | 1 |
| 15 | Transport stress modulates adrenocortieotropin secretion from peripheral bovine lymphocytes 显示文摘 | DIXIT V MARAHRENS M PARVIZI N | 2001 | Journal of Animal Science2001，79，3： | 1 |
| 16 | Microstructural and mechanical properties of friction stir welded Cu- 30Zn brass alloy at various feed speeds: Influence of stir bands 显示文摘 | SARVGHAD MOGHADDAM M PARVIZI R HADDAD?SABZEV AR M DA VOODI A | 2011 | Material Design2011，32，： | 1 |
| 17 | Periprosthetic infection due to resistant staphylococci: serious problems on the horizon 显示文摘 | Parvizi J Azzam K Ghanem E | 2009 | Clin Orthop Relat Res2009，467，： | 1 |
| 18 | Diagnosis of peripros- thetic joint infection using synovial C-reactive protein显示文摘 | Parvizi J Mckenzie JC Cashman JP | 2012 | J Arthroplasty2012，27，8： | 1 |
| 19 | Muhimodal pain man- agement after total joint arthroplasty 显示文摘 | Parvizi J Miller A G Gandhi K | 2011 | J Bone Joint Surg Am2011，93，11： | 1 |
| 20 | Total knee arthroplasty following proximal tibial osteotomy:risk factors for failure显示文摘 | Parvizi J Hanssen AD Spangehl MJ | 2004 | J Bone Joint Surg(Am)2004，86，3： | 1 |
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