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| 1 | Safety impacts of red light running photo enforcement at urban signalized intersections显示文摘Red light running at signalized intersections is a major safety concern in the United States.Statistics showthat approximately 45 percent of crashes at intersections caused by red light running result in severe injuries and fatalities,while only approximately 30 percent of all other types of intersection crashes cause injuries or fatalities. Over the past decade,many US cities and counties have deployed red light running photo enforcement systems for signalized intersections within their jurisdictions to potentially reduce red light running related crashes. This study proposes an empirical Bayesian( EB)before-after analysis method that computes a weighed sumof crashes observed in the field and crashes predicted by safety performance functions( SPFs) to mitigate regression-to-mean biases for analyzing crash reduction effects of red light running enforcement. The analysis explicitly considers red light running related crash types,including head-on,rear-end,angle,turning,sideswipe in the same direction,and sideswipe in the opposite direction; and crash severity levels classified as fatal,injury,and property damage only( PDO). A computational study is conducted to examine the effectiveness of the Chicago programwith red light running photo enforcement systems deployed for nearly two hundred signalized intersections. It is revealed that the use of red light running photo enforcement on the whole is positive,as demonstrated by reductions in all types of fatal crashes by 4-48 percent,and injury-related angle crashes by 1 percent. However,it slightly raises PDO-related angle crashes and moderately increases injury and PDO related rear-end crashes. The safety effectiveness of red light running photo enforcement is sensitive to intersection location. | Yongdoo Lee Zongzhi Li Shengrui Zhang Arash M.Roshandeh Harshingar Patel Yi Liu | 2014 | Journal of Traffic and Transportation Engineering(English Edition)2014,1,5: | 3 |
| 2 | Bloodstream infection rates in outpatient hemodialysis facilities participating in a collaborative prevention effort:a quality improvement report显示文摘 | PATEL P R YI S H BOOTH S | 2013 | American Journal of Kidney Diseases2013,62,2: | 1 |
| 3 | Synthesis,Optical Spectroscopy and Ultrafast Electron Dynamics of PbS Nanoparticles with Different Surface Capping显示文摘 | Amish a Patel Fanxin Wu Jin Z Zhang Claudia L Torres-Martinez Rajesh K Mehra Yi Yang Subhash H Risbud | 2000 | J Phys Chem B2000,104,11: | 1 |
| 4 | Induction of activator protein (AP)-1 and nuclear factor-κB by CD28 stimulation involves both phosphatidylinositol 3-kinase and acidic sphingomylinase signals显示文摘 | Edmead CE Patel YI Wilson A | 1996 | J Immunol1996,157,8: | 1 |
| 5 | Novel role for the innate immune receptor Toll-like receptor 4(TLR4)in the regulation of the Wnt signaling pathway and photoreceptor apoptosis显示文摘 | Yi H Patel AK Sodhi CP | 2012 | PLo S One2012,7,36: | 1 |
| 6 | Bloodstream infection rates in outpatient hemodialysis facilities participating in a col- laborative prevention effort: a quality improvement report 显示文摘 | Patel PR Yi SH Booth S | 2013 | Am J Kidney Dis2013,62,2: | 1 |
| 7 | Novel role for the innate im- mune receptor toll-like receptor4 (TLR4) in the regulation of the wnt signaling pathway and photoreeeptor apoptosis显示文摘 | Yi H Patel AK Sodhi CP | 2012 | PLoS One2012,7,36: | 1 |
| 8 | Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fi- broblasts and glyeolytic tumor ceils in the tumor microenvironment 显示文摘 | Rattigan YI Patel BB Ackemtaff E | 2012 | Exp Cell Res2012,318,4: | 1 |
| 9 | Bloodstream infection rates in outpatient hemodialysis facilities participating in a collaborative prevention effort:a quality improvement report显示文摘 | Patel PR Yi SH Booth S | 2013 | Am J Kidney Dis2013,62,2: | 1 |
| 10 | 活化的巨噬细胞介导的胰岛异种移植排异反应与细胞因子表达上调的关系显示文摘目的:笔者以往的实验证明与猪抗原接触过并被CD4^+T淋巴细胞激活的巨噬细胞能识剐、排斥猪的异种移植物,但不会排斥鼠的同种移植物,这表明在这种特异性移植物免疫识别及破坏过程中移植物及巨噬细胞之间存在着信号联系。方法:在免疫过继转移之前,将胎猪的胰腺碎片移植到非肥胖糖尿病/严重联合免疫缺陷(NOD/SCID)鼠。再从移植了胎猪的胰腺碎片(FPP)并发生排斥反应的受体Balb/c鼠身上分离出巨噬细胞,将这些外源性巨噬细胞植入NOD/SCID鼠。这些外源性的巨噬细胞通过Ly5.1表面抗原或通过CSFE染色标记来追踪。在移植了FPP异种移植物以后的CCR2,CCR5及它们的趋化因子的基因表达可通过实时PCR来评估。结果:形成免疫过继后较早移植的异种移植物出现了免疫排斥,而不是建立免疫过继较长时间后再移植FFP的NOD/SCID鼠。同时,前者可检测出更高水平的趋化因子的基因表达。而且,与未激活的巨噬细胞比较,已经激活的巨噬细胞CCR2,CCR5基因的表达增强更为明显。结论:趋化因子的上调与巨噬细胞的聚集、胰岛移植物的破坏有关。 | Abhilash P. Chandra Li Ou-yang Jeffrey K. W. Wong Hong Ha Stacey N. Waiters Anita T. Patel Wayne J. Hawthorne Shou-nan YI | 2007 | 中南大学学报(医学版)2007,32,1: | 1 |
| 11 | Systemic iron overload associated with welder's siderosis 显示文摘 | Patel R R Yi E S Ryu J H | 2009 | Am J Med Sci2009,337,1: | 1 |
| 12 | Field evaluation of selected light sources for roadway lighting显示文摘The development of new lighting sources, such as light emitting diode(LED), induction,and plasma, presented more possible cost effective ways for roadway lighting. A study was therefore conducted for the Indiana Department of Transportation(INDOT) to evaluate the performance and effectiveness of some selected new lighting devices in roadway lighting.This paper describes the field evaluation process and presents the evaluation results. A number of LEDs, plasma and induction luminaires from various manufacturers were selected to replace the existing high pressure sodium(HPS) lamps in conventional and high mast lightings. Illuminance values were measured over a period of 12 months on the existing and new light sources. Light performance metrics, including illuminance level and uniformity ratios, were calculated to make quantitative comparisons of the HPS and new types of light devices. Based on the evaluation in terms of lighting performance and life cycle costs, it was concluded that LED luminaires should be utilized in roadway lighting in place of HPS luminaires. The results of this study will be useful to state highway and city street agencies in making decisions on their lighting policies and developing technical specifications for use of the new lighting technologies in roadway and street lightings. The study provides a basis for manufacturers to improve their luminaire design and integration to better fit the needs of roadway and street lightings. | Yi Jiang Shuo Li Bowen Guan Guangyuan Zhao Dave Boruff Lalit Garg Prakash Patel | 2018 | Journal of Traffic and Transportation Engineering(English Edition)2018,5,5: | 0 |
| 13 | Role of the immune microenvironment in bone,cartilage,and soft tissue regeneration:from mechanism to therapeuticopportunity显示文摘Bone,cartilage,and soft tissue regeneration is a complex spatiotemporal process recruiting a variety of cell types,whose activity and interplay must be precisely mediated for effective healing post-injury.Although extensive strides have been made in the understanding of the immune microenvironment processes governing bone,cartilage,and soft tissue regeneration,effective clinical translation of these mechanisms remains a challenge.Regulation of the immune microenvironment is increasingly becoming a favorable target for bone,cartilage,and soft tissue regeneration;therefore,an in-depth understanding of the communication between immune cells and functional tissue cells would be valuable.Herein,we review the regulatory role of the immune microenvironment in the promotion and maintenance of stem cell states in the context of bone,cartilage,and soft tissue repair and regeneration.We discuss the roles of various immune cell subsets in bone,cartilage,and soft tissue repair and regeneration processes and introduce novel strategies,for example,biomaterial-targeting of immune cell activity,aimed at regulating healing.Understanding the mechanisms of the crosstalk between the immune microenvironment and regeneration pathways may shed light on new therapeutic opportunities for enhancing bone,cartilage,and soft tissue regeneration through regulation of the immune microenvironment. | Yuan Xiong Bo‑Bin Mi Ze Lin Yi‑Qiang Hu Le Yu Kang‑Kang Zha Adriana CPanayi Tao Yu Lang Chen Zhen‑Ping Liu Anish Patel Qian Feng Shuan‑Hu Zhou Guo‑Hui Liu | 2023 | Military Medical Research2023,10,4: | 0 |