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| 1 | Effect of chain extender structure on the properties and morphology of polyurethanes based on H12MDI and mixed macrodiols (PDMS-PHMO)显示文摘 | ADHIKARI R PATHIRAJA A GUNATILLAKE S J | 1999 | Journal of Applied Polymer Science1999，74，12： | 1 |
| 2 | Chemosynthesis of bioresorbable poly (g-butyrolactone)by ring-opening polymerisation显示文摘 | Tim Moorea Raju Adhikaria Pathiraja Gunatillake | 2005 | Biomaterials2005，26，： | 1 |
| 3 | Effect of chain extender structure on the properties and morphology of polyurethanes based on H12 MDI and mixed macrodiols(PDMS-PHMO)显示文摘 | Adhikari R Pathiraja A | 1999 | Appl Polym Sci1999，74，： | 1 |
| 4 | Effect of polydimethylsiloxane maerodiol molecular weight on properties and morphology of polyurethane and polyurethaneurea 显示文摘 | Raju Adhikari Pathiraja A Gunatillake Mark Bown | 2003 | Journal of Applied Polymer Science2003，90，： | 1 |
| 5 | Synthesis of cleavable multi-functional mikto-arm star polymer by RAFT polymerization: example of an anti-cancer drug 7-ethyl-10-hydroxycamptothecin(SN-38) as functional moiety显示文摘Multi-functional mikto-arm star polymers containing three different arms[hydrophilic,SN-38-P(OEGMA8?9)11,cationizable,SN-38-P(DMAEMA)38 and hydrophobic,SN-38-P(BMA)26]were prepared by RAFT polymerization via an arm-first approach using a cleavable cross-linker.The star polymers were cleaved to the linear arms with tributylphosphine as a reducing agent.The decrease in molecular weight observed is consistent with the initial stars having approximately five arms.Blue fluorescence was observed when a solution of mikto-arm star was irradiated under a 365 nm light proving the retention of the SN-38moiety during star formation by RAFT polymerization.Thus these polymer-drug conjugates can be considered as potential delivery vehicles for cancer therapy.The P(DMAEMA)arms can be quaternized using iodomethane,allowing star polymers to bind negatively charged small interfering RNA(siRNA)and potentially be used as a carrier for that material. | WEI XiaoHu GUNATILLAKE Pathiraja A MOAD Graeme RIZZARDO Ezio ROSSELGONG Julien YANG WanTai THANG San H. | 2014 | Science China Chemistry2014，57，7： | 1 |
| 6 | Risperidone: clinical saferty and efficacy in schizophrenia 显示文摘 | Borisin RL Pathiraja AP Diamond BL | 1992 | J Psychopharmacol1992，28，： | 1 |
| 7 | Effect of pre-existing anti-diphtheria toxin antibodies on T cell depletion levels following diphtheria toxin-based recombinant anti-monkey CD3immunotoxin treatment 显示文摘 | Abraham J Matar Vimukthi Pathiraja Zhirui Wang | 2012 | Transplant Immunology2012，27，1： | 1 |
| 8 | Serous endometrial intraepithelial carcinoma:a case series and literature review显示文摘 | Pathiraja P Dhar S Haldar K | | 0，，： | 1 |
| 9 | Progesterone receptor isoform-specific promoter methylation:association of PRA promoter methylation with worse outcome in breast cancer patients显示文摘 | Pathiraja TN Shetty PB Jelinek J | 2011 | Clin Cancer Res2011，17，12： | 1 |
| 10 | 显示文摘 | Pathiraja A Gordon F Simon J | 1998 | Journal of Applied Polymers Science1998，69，8： | 1 |
| 11 | Concussion:comparison of humans and rats显示文摘 | Parkinson D West M Pathiraja T | 1978 | Neurosurgery1978，3，2： | 1 |
| 12 | Epigenetic Regulation in Estrogen Receptor Positive Breast Cancer-Role in Treatment Response显示文摘 | Thushangi N Pathiraja Vered Stearns | 2010 | J Mammary Gland Biol Neopla- sia2010，15，： | 1 |
| 13 | Epigenetic regulation in es- trogen receptor positive breast cancer- role in treatment response显示文摘 | Pathiraja TN Steams V Oesterreich S | 2010 | J Mammary Gland Biol Neoplasia2010，15，1： | 1 |
| 14 | 直肠检查诊断瘤牛黄体的准确性显示文摘在75头白色福兰尼(White Flanl)母牛(瘤牛)中测定了触诊黄体和血浆孕酮之间的相互关系,检查了178头母牛,有75头可触摸到黄体,根据直径,黄体可被分为两种类型:黄体(cl)<1.5cm和黄体(cl)、≥1.5cm,在75头可触摸到黄体的母牛中,有55头(77%)通过测定血浆中孕酮浓度证实为机能性黄体(functional corpora lutea)。黄体>1.5cm组,直肠触诊的准确性显著地高于黄体<1.5cm组(p<0.05),而在调查者诊断之间没有显著性差异,结果表明:瘤牛卵巢黄体诊断的准确性是比较高的,然而,利用黄体大小来测定它的发育阶段和机能的程度上作为一个有用的标准尺度是不明显的。 | N·pathiraja 许宗运 | 1989 | 中国牦牛1989，，1： | 0 |
| 15 | Dietary sophorolipid accelerates growth by modulation of gut microbiota population and intestinal environments in broiler chickens显示文摘Background:Gut is a crucial organ for the host’s defense system due to its filtering action of the intestinal membrane from hazardous foreign substances.One strategy to strengthen the gut epithelial barrier function is to upregulate beneficial microflora populations and their metabolites.Sophorolipid(SPL),which is a glycolipid biosurfactant,could increase beneficial microflora and decrease pathogenic bacteria in the gastrointestinal tract.Therefore,herein,we conducted an experiment with broiler chickens to investigate the fortifying effects of SPL on the host’s gut defense system by modulating the microbiota population.Methods:A total of 5401-day-old chicks(Ross 308)were used,and they were immediately allotted into three treatment groups(6 replications with 30 chicks/pen)according to their initial body weight.The dietary treatments consisted of CON(basal diet),BAM(10 mg/kg bambermycin),and SPL(10 mg/kg SPL).During the experiment,birds freely accessed feed and water,and body weight and feed intake were measured at the end of each phase.On d 35,birds(one bird/pen)were sacrificed to collect jejunum and cecum samples.Results:Dietary SPL and BAM supplementation significantly accelerated birds’growth and also significantly improved feed efficiency compared to CON.Intestinal microbial community was significantly separated by dietary SPL supplementation from that of CON,and dietary SPL supplementation significantly increased Lactobacillus spp.and Akkermansia muciniphila.Moreover,birds fed with dietary SPL also showed the highest concentration of cecal butyrate among all treatment groups.Gut morphological analysis showed that dietary SPL significantly increased villus height,ratio of villus height to crypt depth,goblet cell numbers,and the gene expression levels of claudin-1 and mucin 2.Additionally,dietary SPL significantly decreased the mRNA expression level of pro-inflammatory cytokine,interleukin-6,and increased that of anti-inflammatory cytokine,interleukin-10,compared to other treatments.Conclusions:Dietary SPL increases the beneficial bacterial population and butyrate concentration,which leads to a strengthened gut barrier function.In addition,the intestinal inflammation was also downregulated by dietary SPL supplementation. | Min-Jin Kwak Min-Young Park Yong-Soon Choi Junghwan Cho Duleepa Pathiraja Jonggun Kim Hanbae Lee In-Geol Choi Kwang-Youn Whang | 2022 | Journal of Animal Science and Biotechnology2022，13，1： | 0 |
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