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| 1 | An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond. | Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg | 2018 | Horticulture Research2018，5，1： | 10 |
| 2 | Uncoupling of glomerular and tubular regulations of urea excretion in rat显示文摘 | Peil AE Stolte H Schmidt-Nielsen B | 1990 | Am J Physi- ol1990，258，： | 1 |
| 3 | Pain measurement:visual analogue scale(VAS)and verbal rating scale(VRS)in clinical trials with OTC analgesics in headache显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalalgia2012，32，3： | 1 |
| 4 | Development of a multiallelic SCAR marker for the scab resistance gene Vr1/Vh4/ Vx from R12740-TA apple and its utility for molecular breeding显示文摘 | Boudichevskaia A Flachowsky H Peil A | 2006 | Tree Genetics & Genomes2006，2，4： | 1 |
| 5 | Pain measurement: Visual Analogue Scale (VAS) and Verbal Rating Scale (VRS) in clinical trials with OTC analgesics in headache 显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalalgia2012，32，3： | 1 |
| 6 | Dynamic behaviour of guys under turbulent wind load显示文摘 | Peil U Nolle H WANG Zhi-hong | 1996 | Journal of Wind Engineering and Industrial Aerodynamics1996，，65： | 1 |
| 7 | Pain measurement Vi- sual Analogue Scale (VAS) and Verbal Rating Scale (VRS) in clinical trials with OTC analgesics in headache 显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalalgia2012，32，3： | 1 |
| 8 | Pain measurement:Visual Analogue Scale(VAS)and Verbal Rating Scale(VRS)in clinical trials with OTC analgesics in headache显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalalgia2012，32，3： | 1 |
| 9 | Pain measurement: Visual An-alogue Scale (VAS) and Verbal Rating Scale ( VRS) in clini-cal trials with OTC analgesics in headache显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalalgia2012，32，3： | 1 |
| 10 | Pain measurement:Visual Analogue Scale(VAS)and Verbal Rating Scale(VRS)in clinical trials with OTC analgesics in headache显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalalgia2012，32，3： | 1 |
| 11 | A comprehensive study of the relationship between enterprise resource planning selection criteria and enterprise resource planning system success显示文摘 | Tsai W H Lee Peiling Shen Yushan | 2012 | Information & Management2012，49，1： | 1 |
| 12 | Pain measurement: Visual Analogue Scale (VAS) and Verbal Rating Scale (VRS) in clinical trials with OTC analgesics in headache 显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalal- gia2012，32，3： | 1 |
| 13 | A review on transgenic approaches to accelerate breeding of woody plants 显示文摘 | FLACHOWSKY H HANKE M V PEIL A et 01 | 2009 | Plant Breed2009，128，： | 1 |
| 14 | Pain measurement:Visual Analogue Scale(VAS)and Verbal Rating Scale(VRS)in clinicaltrials with OTC analgesics in headache显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalalgia2012，32，3： | 1 |
| 15 | Simultaneous determination of synthetic phosphodiesterase-5 inhibitors found in a dietary supplement and pre-mixed bulk powders for dietary supplements using high-performance liquid chromatography with diode array detection and liquid chromatography-electrospray ionization tandem mass spectrometry显示文摘 | PENG Z SHARON S Y PEILING H | 2006 | J Chromatogr A2006，1104，： | 1 |
| 16 | Graduate entry medicine: curriculum considerations 显示文摘 | Yvonne H Carter Ed Peile | 2007 | Clinical Medicine2007，7，3： | 1 |
| 17 | Pain measurement: Visual Analogue Scale ( VAS ) and Verbal Rating Scale ( VRS ) in clinical trials with OTC analgesics in headache 显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalalgia2012，32，3： | 1 |
| 18 | Guyed masts under wind load显示文摘 | Peil U Nolle H | 1992 | J Wind Engng Indust Aerodynam1992，4144，： | 1 |
| 19 | Pain measurement:visual analogue scale(VAS)and verbal rating scale(VRS)in clinical trials with OTC analgesics in headache显示文摘 | Aicher B Peil H Peil B | 2012 | Cephalalgia2012，32，3： | 1 |
| 20 | Development of a multiallelic SCAR marker for the scab resistance gene Vr1/Vh4/Vx from R12740-7A apple and its utility for molecular breeding显示文摘 | Boudichevskaia A Flachowsky H Peil A | 2006 | Tree Genetics & Genomes2006，2，4： | 1 |
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