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1篇 您的检索式:作者名="Peter Milassin"
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1A case of interstitial pneumonitis in a patient with ulcerative colitis treated with azathioprine显示文摘The early hypersensitivity reaction and late bone marrow depression are well-known side-effects of azathioprine, whereas interstitial pneumonia is a rare complication. A 40-year old male patient had been treated with azathioprine in consequence of extensive ulcerative colitis for 10 years. He then complained of 7 d of fever, cough and catarrhal signs, without symptoms of active colitis. Opportunistic infections were ruled out. The chest X-ray, CT and lung biopsy demonstrated the presence of interstitial inflammation. Azathioprine therapy was discontinued as a potential source of the pulmonary infiltrate. In response to steroid therapy, and intensive care, the pulmonary infiltrate gradually decreased within 4 wk. Three months later, his ulcerative colitis relapsed, and ileo-anal pouch surgery was performed. In cases of atypical pneumonia, without a proven infection, azathioprine-associated interstitial pneumonitis may be present, which heals after withdrawal of the drug.Ferenc Nagy Tamas Molnar Eva Makula Ildiko Kiss Peter Milassin Eva Zollei Laszlo Tiszlavicz Janos Lonovics 2007World Journal of Gastroenterology2007,13,2:1
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