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| 1 | Intra-operative frozen section diagnosis of breast lesions:a retrospective analysis of 13 243 Chinese patients显示文摘背景尽管为胸肿瘤学的 cytological 方法在最近的十年被使用了, intra 起作用的冻结的节在做治疗学的决定一直在起一个重要作用。我们分析了冻结的节的一个大系列最后 15 年为汉语诊断在内的胸损害的盒子。经验被期望与胸 lesions.Methods 增加盒子的诊断精确性数据从连续与在 1988 ~ 2002 之间的 intra 起作用的冻结的节诊断的胸损害的 13243 个盒子与在由盒子举止的一种情况中的石蜡节相比。原因假否定、积极诊断象一样推迟诊断是 analyzed.Results 117 个盒子(0.9%) 虚伪地被诊断,与一个假积极盒子和 116 个假否定盒子。47 个盒子(0.4%) 的诊断被推迟。几损害的比例有 patients'ages 的特征。损害的六种类型(假侵略,仙子乳突淋瘤,乳头管的腺瘤,红润的 adenosis , sclerosing adenosis ,和淀粉粒质房间肿瘤)可以导致假积极,并且四种类型(词法变化反应化疗,很好区分的乳突的癌,侵略的小叶片的癌,并且管状的癌)到一假否定。粗野、显微镜的调查结果可能在在三的显微镜、临床的调查结果打的损害(光线的疤和红润的 adenosis ) 的二种类型是不一致的(ganulomatous 乳腺炎乳房,管 ectasia,和胖坏死) ,并且三种类型(丰富的胖或硬术的纸巾;边线损害和变化化疗以后) 错误地是可能的 Intra 起作用的冻结的节能精确地识别的 classified.Conclusions 在许多例子的胸损害,由于诊断限制的更诊断的经验和理解,导致更少错误。 | NIU Yun FU Xi-lin YU Yong Peizhong Peter Wang CAO Xu-chen | 2007 | Chinese Medical Journal2007，，8： | 11 |
| 2 | Validity assessment and determination of the cutoff value for the Index of Complexity, Outcome and Need among 12-13 year-olds in Southern Chinese显示文摘To validate the use of the Index of Complexity,Outcome and Need (ICON) in assessing orthodontic treatment need among 12-13 year-olds in southern China,we determined the threshold value of ICON based on Chinese orthodontists' judgments. The samples consisted of 335 students in grade 7 from 16 randomly selected middle schools in Chengdu,China. Three associate professors provided ICON scores for each participant and the results were compared with the gold standard judgments from 25 experts on treatment needs. Based on the gold standard,195 casts belonged to the treatment category,while the rest 140 belonged to the no-treatment category. With the international cutoff point of 43,the sensitivity and specificity of the ICON score were 0.29 and 0.98. The best compromise between sensitivity and specificity in Chengdu,compared with the gold standard,was found at a cutoff point of 29,and the sensitivity and specificity were 0.88 and 0.83. When used to evaluate the treatment need of 12-13 year-olds in southern China,the international ICON cutoff value did not correspond well with Chinese orthodontists' judgments; a lower cutoff value of 29 offered a greater sensitivity and specificity with respect to expert orthodontists' perception of treatment need. | Zheng-Yu Liao Fan Jian Hu Long Yun Lu Yan Wang Zhi Yang Yu-Wei He Peter Wamalwa Jing Wang Nian-Song Ye Sheng Wang Wen-Li Lai | 2012 | International Journal of Oral Science2012，4，2： | 5 |
| 3 | Performance of broiler chickens offered nutritionally-equivalent diets based on two red grain sorghums with quantified kafirin concentrations as intact pellets or re-ground mash following steam-pelleting at65 or 97℃ conditioning temperatures显示文摘The Liverpool Plains is a fertile agricultural region in New South Wales, Australia. Two sorghums from the2009 Liverpool Plains harvest, sorghums #3 and #5, were extensively characterised which included concentrations of kafirin and phenolic compounds plus rapid visco-analysis(RVA) starch pasting profiles. Diets based on these two sorghums were formulated to be iso-nitrogenous and iso-energetic and were offered to male Ross 308 broiler chicks from 7 to 28 days post–hatch as either intact pellets or reground mash following steam-pelleting at conditioning temperatures of either 65 or 97°C. Thus the feeding study consisted of a 2×2×2 factorial array of dietary treatments: two sorghum varieties, two feed forms and two conditioning temperatures. Each of the eight treatments was replicated six times with six birds per replicate cage.Assessed parameters included growth performance, nutrient utilisation, apparent starch and protein(N) digestibility coefficients and disappearance rates from the distal jejunum and distal ileum. Intact pellets supported higher(P <0.001) feed intakes and weight gains by 9.83 and 9.08%, respectively, than reground mash diets. Feed conversion ratios of broilers offered diets steam-conditioned at 97°C were 2.46% inferior(P <0.001) in comparison to 65°C diets and both apparent metabolizable energy(AME) and N-corrected AME(AMEn) were compromised. Broilers offered sorghum #3-based diets significantly(P <0.001) outperformed their sorghum #5 counterparts in terms of weight gain by 3.75%(1,334 versus 1,223 g/bird), FCR by 4.81%(1.524 versus 1.601), AME by 1.06 MJ(13.61 versus 12.55 MJ/kg), ME:GE ratio(ME:GE) by 4.81%(0.806 versus0.769) and AMEn by 1.03 MJ(12.38 versus 11.35 MJ/kg). The inferiority of sorghum #5 appeared to be associated with higher concentrations of kafirin(61.5 versus 50.7 g/kg) and conjugated phenolic acids,including ferulic acid(31.1 versus 25.6 mg/g). There were no significant differences in jejunal and ileal starch and protein(N) digestibility coefficients between the two sorghums. However, starch to protein(N) disappearance rate ratios from the distal jejunum were significantly(P <0.001) correlated with ME:GE and AME. The multiple linear regression equations indicated that energy utilisation was enhanced by coupling rapidly digestible protein with slowly digestible starch, which suggests that bilateral bioavailability of starch and protein is pivotal to efficient energy utilisation. | Ha H.Truong Karlie A.Neilson Bernard V.McInerney Ali Khoddami Thomas H.Roberts Sonia Yun Liu Peter H.Selle | 2015 | Animal Nutrition2015，，3： | 5 |
| 4 | Progress towards reduced-crude protein diets for broiler chickens and sustainable chicken-meat production显示文摘The prime purpose of this review is to explore the pathways whereby progress towards reduced-crude protein(CP)diets and sustainable chicken-meat production may be best achieved.Reduced-CP broiler diets have the potential to attenuate environmental pollution from nitrogen and ammonia emissions;moreover,they have the capacity to diminish the global chicken-meat industry’s dependence on soybean meal to tangible extents.The variable impacts of reduced-CP broiler diets on apparent amino acid digestibility coefficients are addressed.The more accurate identification of amino acid requirements for broiler chickens offered reduced-CP diets is essential as this would diminish amino acid imbalances and the deamination of surplus amino acids.Deamination of amino acids increases the synthesis and excretion of uric acid for which there is a requirement for glycine,this emphasises the value of so-called“non-essential”amino acids.Starch digestive dynamics and their possible impact of glucose on pancreatic secretions of insulin are discussed,although the functions of insulin in avian species require clarification.Maize is probably a superior feed grain to wheat as the basis of reduced-CP diets;if so,the identification of the underlying reasons for this difference should be instructive.Moderating increases in starch concentrations and condensing dietary starch:protein ratios in reduced-CP diets may prove to be advantageous as expanding ratios appear to be aligned to inferior broiler performance.Threonine is specifically examined because elevated free threonine plasma concentrations in birds offered reduced-CP diets may be indicative of compromised performance.If progress in these directions can be realised,then the prospects of reduced-CP diets contributing to sustainable chicken-meat production are promising. | Sonia Yun Liu Shemil P.Macelline Peter V.Chrystal Peter H.Selle | 2021 | Journal of Animal Science and Biotechnology2021，12，3： | 5 |
| 5 | Reducing agent and exogenous protease additions,individually and in combination, to wheat-and sorghum-based diets interactively influence parameters of nutrient utilisation and digestive dynamics in broiler chickens显示文摘The objective of the study was to investigate the possibility that tandem inclusions of a reducing agent and a protease may advantage chicken-meat production and to ascertain if the established benefits of including sodium metabisulphite in sorghum-based diets extend to wheat-based diets. The study comprised a 2 x 2 x 2 factorial array of treatments in which either nutritionally iso-nitrogenous and isoenergetic wheat-or sorghum-based diets, without and with sodium metabisulphite(2.75 g/kg), without and with protease(1,000 units/kg) were offered to broiler chickens from 7 to 28 days post-hatch. The effects of dietary treatments on growth performance, nutrient utilisation, protein(N) and starch digestibility coefficients and digestive dynamics were determined. A preliminary investigation into the effects of two treatments on concentrations of free amino acids and glucose in the portal circulation was conducted. There was significant feed grain by sodium metabisulphite interactions(P = 0.03 to 0.005) for parameters of nutrient utilisation(AME, ME:GE ratios, N retention, AMEn). For example, sodium metabisulphite inclusions in sorghum-based diets enhanced AME by 0.18 MJ(12.47 versus 12.29 MJ/kg) but depressed AME by 0.43 MJ(11.88 versus 12.31 MJ/kg) in wheat-based diets. There was a linear relationship between starch:protein disappearance rate ratios in the distal ileum with weight gain(r =-0.484; P = 0.0012) indicating that condensed ratios(or absorption of more protein relative to starch) advantaged growth performance. Concentrations of free amino acids in the portal circulation or the post-enteral availability of certain amino acids, including the branched-chain amino acids, methionine, phenylalanine and threonine, were significantly correlated to FCR. For example, threonine concentrations were negatively correlated to FCR(r =-0.773; P = 0.005). Finally, tandem inclusions of sodium metabisulphite and protease in sorghum-based diets may hold merit but it appears that the established 'energy sparing' effects of sodium metabisulphite inclusions in sorghum-based diets are not duplicated in wheat-based diets. | Peter H.Selle Ha H.Truong Leon R.McQuade Amy F.Moss Sonia Yun Liu | 2016 | Animal Nutrition2016，，4： | 3 |
| 6 | Subtype-Specific MEK-PI3 Kinase Feedback as a Therapeutic Target in Pancreatic Adenocarcinoma显示文摘 | Olga K. Mirzoeva Eric A. Collisson Peter M. Schaefer Byron Hann Yun K. Hom Andrew H. Ko W. Michael Korn | 2013 | Molecular Cancer Therapeutics2013，，10： | 2 |
| 7 | High-sensitivity nanophotonic sensors with passive trapping of analyte molecules in hot spots显示文摘Nanophotonic resonators can confine light to deep-subwavelength volumes with highly enhanced near-field intensity and therefore are widely used for surface-enhanced infrared absorption spectroscopy in various molecular sensing applications.The enhanced signal is mainly contributed by molecules in photonic hot spots,which are regions of a nanophotonic structure with high-field intensity.Therefore,delivery of the majority of,if not all,analyte molecules to hot spots is crucial for fully utilizing the sensing capability of an optical sensor.However,for most optical sensors,simple and straightforward methods of introducing an aqueous analyte to the device,such as applying droplets or spin-coating,cannot achieve targeted delivery of analyte molecules to hot spots.Instead,analyte molecules are usually distributed across the entire device surface,so the majority of the molecules do not experience enhanced field intensity.Here,we present a nanophotonic sensor design with passive molecule trapping functionality.When an analyte solution droplet is introduced to the sensor surface and gradually evaporates,the device structure can effectively trap most precipitated analyte molecules in its hot spots,significantly enhancing the sensor spectral response and sensitivity performance.Specifically,our sensors produce a reflection change of a few percentage points in response to trace amounts of the amino-acid proline or glucose precipitate with a picogram-level mass,which is significantly less than the mass of a molecular monolayer covering the same measurement area.The demonstrated strategy for designing optical sensor structures may also be applied to sensing nano-particles such as exosomes,viruses,and quantum dots. | Xianglong Miao Lingyue Yan Yun Wu Peter Q.Liu | 2021 | Light(Science & Applications)2021，10，1： | 2 |
| 8 | Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes显示文摘 | Xin Yuan Dawn Waterworth John R.B. Perry Noha Lim Kijoung Song John C. Chambers Weihua Zhang Peter Vollenweider Heide Stirnadel Toby Johnson Sven Bergmann Noam D. Beckmann Yun Li Luigi Ferrucci David Melzer Dena Hernandez Andrew Singleton James Scott Paul | 2008 | The American Journal of Human Genetics2008，，4： | 1 |
| 9 | Wavelet Based Image Fusion Techniques-An Introduction Review and Comparison显示文摘 | Kriste Amolins Yun Zhang Peter Dare | 2007 | ISPRS Journal of Photogrammetry & Remote Sensing2007，62，4： | 1 |
| 10 | Comparative study on the films of poly (vinyl alcohol)/pea starch nanocrystals and poly( vinyl alcohol)/native pea starch 显示文摘 | Yun Chen Xiaodong Cao Peter R Chang | 2008 | Carbohydrate Polymers2008，73，1： | 1 |
| 11 | Wavelet based Image Fusion Techniques - Anintroduction, Review and Comparison显示文摘 | Krista Amolins Yun Zhang and Peter Dare | 2007 | ISPRS Journal of Photogrammetry and Remote Sensing2007，62，4： | 1 |
| 12 | Role of Chemotactic Factors in Neutrophil Activation After Thermal Injury in Rats显示文摘 | Maria-Thereza S. Piccolo Yun Wang Serge Verbrugge Roscoe L. Warner Paulina Sannomiya Nelson S. Piccolo Monica S. Piccolo Tony E. Hugli Peter A. Ward Gerd O. Till | 1999 | Inflammation1999，，4： | 1 |
| 13 | Wavelet based image fusion techniques-An introduction review and comparison 显示文摘 | Kriste Amolins Yun Zhang Peter Dare | 2007 | ISPRS Journal of Photogratmnetry & Remote Sensing2007，62，2007： | 1 |
| 14 | Wavelet based image fu- sion techniques-an introduction, review and comparison 显示文摘 | Amolins K Yun Z Dare Peter | 2007 | ISPRS Journal of Phototrammetry & Remote Sens- ing2007，62，4： | 1 |
| 15 | Solid-solution phase formation rules for multi-component alloys 显示文摘 | ZHANG Y YUN J Z JUN P L GUO L C PETER K | 2008 | Advanced Engineering Materials2008，10，： | 1 |
| 16 | Picomolar-sensitiveβ-amyloid fibril fluorophores by tailoring the hydrophobicity of biannulatedπ-elongated dioxaborine-dyes显示文摘The pathological origin of Alzheimer’s disease(AD)is still shrouded in mystery,despite intensive worldwide research efforts.The selective visualization ofβ-amyloid(Aβ),the most abundant proteinaceous deposit in AD,is pivotal to reveal AD pathology.To date,several small-molecule fluorophores for Aβspecies have been developed,with increasing binding affinities.In the current work,two organic small-molecule dioxaborine-derived fluorophores were rationally designed through tailoring the hydrophobicity with the aim to enhance the binding affinity for Aβ_(1-42) fibrils-while concurrently preventing poor aqueous solubility-via biannulate donor motifs in D-π-A dyes.An unprecedented sub-nanomolar affinity was found(K_(d)=0.62±0.33 nM)and applied to super-sensitive and red-emissive fluorescent staining of amyloid plaques in cortical brain tissue ex vivo.These fluorophores expand the dioxaborine-curcumin-based family of Aβ-sensitive fluorophores with a promising new imaging agent. | Jusung An Peter Verwilst Hira Aziz Jinwoo Shin Sungsu Lim Ilwha Kim Yun Kyung Kim Jong Seung Kim | 2022 | Bioactive Materials2022，7，7： | 1 |
| 17 | Structure and properties of starch/α-zirconium phosphate nanocomposite films显示文摘 | Haixia Wu Changhua Liu Jianguang Chen Peter R. Chang Yun Chen Debbie P. Anderson | 2009 | Carbohydrate Polymers2009，，2： | 1 |
| 18 | Wavelet based image fusion techniques--An introduction, review and comparison 显示文摘 | Amolins Krista Zhang Yun Dare Peter | 2007 | ISPRS Journal of Photogrammetry & Remote Sensing2007，62，4： | 1 |
| 19 | Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci显示文摘 | Richa Saxena Clara C. Elbers Yiran Guo Inga Peter Tom R. Gaunt Jessica L. Mega Matthew B. Lanktree Archana Tare Berta Almoguera Castillo Yun R. Li Toby Johnson Marcel Bruinenberg Diane Gilbert-Diamond Ramakrishnan Rajagopalan Benjamin F. Voight Ashok Bala | 2012 | The American Journal of Human Genetics2012，，4： | 1 |
| 20 | Highly compact and uniform CH3NH3Sn0.5Pb0.5I3 films for efficient panchromatic planar perovskite solar cells显示文摘An efficient panchromatic planar perovskite solar cell is developed based on highly uniform,lead-reduced CH3NH3Sn0.5Pb0.5I3 perovskite films with full film-coverage on the substrates.We demonstrate here that full-coverage of the CH3NH3Sn0.5Pb0.5I3 films can be developed by a facile chlorobenzene-assisted spin-coating method.A power conversion efficiency of 7 % is achieved using low-temperature processes,which is among the best-reported performance for panchromatic planar perovskite solar cells with a light-absorption over 1,000 nm. | Miaoqiang Lyu Meng Zhang Nathan A. Cooling Yalong Jiao Qiong Wang Jung-Ho Yun Ben Vaughan Gerry Triani Peter Evans Xiaojing Zhou Krishna Feron Aijun Du Paul Dastoor Lianzhou Wang | 2016 | Science Bulletin2016，61，20： | 1 |
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