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| 1 | Chemotherapy-induced neutropenia and treatment efficacy in advanced non-small-cell lung cancer: a pooled analysis of three randomised trials显示文摘 | Massimo Di Maio Cesare Gridelli Ciro Gallo Frances Shepherd Franco Vito Piantedosi Silvio Cigolari Luigi Manzione Alfonso Illiano Santi Barbera Sergio Federico Robbiati Luciano Frontini Elena Piazza Giovanni Pietro Ianniello Enzo Veltri Federico Castiglio | 2005 | Lancet Oncology2005,,9: | 2 |
| 2 | An early evaluation of translocation actions for endangered plant species on Mediterranean islands显示文摘In situ conservation is widely considered a primary conservation strategy. Plant translocation, specifically, represents an important tool for reducing the extinction risk of threatened species. However, thus far, few documented translocations have been carried out in the Mediterranean islands. The CareMediflora project, carried out on six Mediterranean islands, tackles both short-and long-term needs for the insular endangered plants through in situ and ex situ conservation actions. The project approach is based on using ex situ activities as a tool to improve in situ conservation of threatened plant species.Fifty island plants(representing 45 taxa) were selected for translocations using common criteria.During the translocations, several approaches were used, which differed in site selection method, origin of genetic material, type of propagative material, planting method, and more. Although only preliminary data are available, some general lessons can be learned from the experience of the CareMediflora project. Among the factors restricting the implementation of translocations, limited financial resources appear to be the most important. Specific preliminary management actions, sometimes to be reiterated after translocation, increase the overall cost, but often are necessary for translocation success. Translocation using juvenile/reproductive plants produces better results over the short term,although seeds may provide good results over the long run(to be assessed in the future). Regardless,plant translocation success can only be detected over long periods; therefore, proper evaluation of plant translocations requires a long-term monitoring protocol. Care-Mediflora project represents the first attempt to combine the existing approaches in a common plant conservation strategy specifically focusing on the Mediterranean islands. | Giuseppe Fenu Gianluigi Bacchetta S.Christodoulou Charalambos Christini Fournaraki Gian Pietro Giusso del Galdo Panagiota Gotsiou Angelos Kyratzis Carole Piazza Magdalena Vicens Maria Silvia Pinna Bertrand de Montmollin | 2019 | Plant Diversity2019,41,2: | 1 |
| 3 | New imaging technologies for robotic kidney cancer surgery显示文摘Objective:Kidney cancers account for approximately 2%of all newly diagnosed cancer in 2020.Among the primary treatment options for kidney cancer,urologist may choose between radical or partial nephrectomy,or ablative therapies.Nowadays,robotic-assisted partial nephrectomy(RAPN)for the management of renal cancers has gained popularity,up to being considered the gold standard.However,RAPN is a challenging procedure with a steep learning curve.Methods:In this narrative review,different imaging technologies used to guide and aid RAPN are discussed.Results:Three-dimensional visualization technology has been extensively discussed in RAPN,showing its value in enhancing robotic-surgery training,patient counseling,surgical planning,and intraoperative guidance.Intraoperative imaging technologies such as intracorporeal ultrasound,near-infrared fluorescent imaging,and intraoperative pathological examination can also be used to improve the outcomes following RAPN.Finally,artificial intelligence may play a role in the field of RAPN soon.Conclusion:RAPN is a complex surgery;however,many imaging technologies may play an important role in facilitating it. | Stefano Puliatti Ahmed Eissa Enrico Checcucci Pietro Piazza Marco Amato Stefania Ferretti Simone Scarcella Juan Gomez Rivas Mark Taratkin Jose Marenco Ines Belenchon Rivero Karl-Friedrich Kowalewski Giovanni Cacciamani Ahmed El-Sherbiny Ahmed Zoeir Abdelhamid MEl-Bahnasy Ruben De Groote Alexandre Mottrie Salvatore Micali | 2022 | Asian Journal of Urology2022,9,3: | 0 |
| 4 | Initial experience of a single center with the use of ZSI 475 penile prosthesis显示文摘Objective:To evaluate surgical outcomes after implantation of the Zephyr ZSI 475 inflatable penile prosthesis(IPP)and patients’quality of life.Methods:From December 2014 to September 2018,15 patients underwent prosthesis implantation with ZSI 475.A retrospective review of clinical data was performed.Patients’quality of life after implantation was investigated with Quality of Life and Sexuality with Penile Prosthesis(QoLSPP)questionnaire.Results:The median age of patients was 57 years and the average follow-up time was 22 months.Twelve patients received a standard implantation due to severe erectile dysfunction(ED);three patients also presented penile curvature and additional corporoplasty with grafting was necessary.Three procedures had to be interrupted due to defects of the insertion tools.In one case a manufacturing defect resulted in a pump leak.In one case,a severe postoperative complication occurred,which requested explanation of the device.During the follow-up,four patients experienced mechanical failure of the prosthesis.Results of QoLSPP questionnaire at 12 months were skewed toward the positive end of the scale in all domains.Conclusion:In our initial experience,ZSI 475 suffered a high rate of mechanical failures;on the other hand,the company showed great commitment in order to improve the quality and reliability of the device.The lower cost of ZSI 475 may add to the chances of the product to become a cost-effective alternative to treat those patient who need a IPP. | Fulvio Colombo Giorgio Gentile Valerio Vagnoni Alessandro Fiorillo Pietro Piazza Fabrizio Sartorio Alessandro Franceschelli | 2021 | Asian Journal of Urology2021,8,2: | 0 |
| 5 | 新型营养合剂通过一氧化氮依赖机制降低高血压患者血压并增强其运动功能显示文摘长期以来,高血压被认为是一种对健康构成主要威胁的疾病,尤其是脑卒中、心血管病和终末器官损害的危险因素。因此,需要确定一种控制血压和保护心血管的新型可替代的综合疗法。方法和结果:在2项双盲研究中纳入年龄40~68岁,服用降压药的未控制高血压患者69例。45例患者随机服用安慰剂或一种名为AkP05的新型营养合剂,在基线及4周治疗后评估血压、内皮功能和循环一氧化氮水平。 | 袁源(摘译) 练桂丽(审校) Carrizzo A Moltedo O Damato A Martinello K Di Pietro P Oliveti M Acernese F Giugliano G Izzo R Sommella E Migliarino S Piazza O Izzo C Virtuoso N Strianese A Trimarco V Campiglia P Fucile S Puca A Trimarco B Vecchione C | 2020 | 中华高血压杂志2020,28,11: | 0 |