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13篇 您的检索式:作者名="Pietro Tundo"
    题名 作者 年代 出处 被引量
1New developments in dimethyl carbonate chemistry 显示文摘Pietro Tundo 2001Pure and Applied Chemistry2001,73,:1
2Facile hydrodehalogenation with H2 and Pd/C catalyst under multiphase conditions显示文摘Carlos Alberto Marques Maurizio Selva Pietro Tundo 0,,:1
3Multiphase oxidation of alcohols and sulfides with hydrogen peroxide catalyzed by heteropolyacids显示文摘Tundo Pietro Romanelli Gustavo P Vazquez Patricia G 2010Catalysis Communications2010,11,:1
4Boceprevir or telaprevir in hepatitis C virus chronic infection:The Italian real life experience显示文摘AIM: To check the safety and efficacy of boceprevir/telaprevir with peginterferon/ribavirin for hepatitis C virus(HCV) genotype 1 in the real-world settings. METHODS: This study was a non-randomized, observational, prospective, multicenter. This study involved 47 centers in Italy. A database was prepared for the homogenous collection of the data, was used by all of the centers for data collection, and was updated continuously. All of the patients enrolled in this study were older than 18 years of age and were diagnosed with chronic infection due to HCV genotype 1. The HCV RNA testing was performed using COBAS-Taq Man2.0(Roche, LLQ 25 IU/m L). RESULTS: All consecutively treated patients were included. Forty-seven centers enrolled 834 patients as follows: Male 64%; median age 57(range 18-78), of whom 18.3% were over 65; mean body mass index 25.6(range 16-39); genotype 1b(79.4%); diagnosis of cirrhosis(38.2%); and fibrosis F3/4(71.2%). The following drugs were used: Telaprevir(66.2%) and PEG-IFN-alpha2a(67.6%). Patients were na?ve(24.4%), relapsers(30.5%), partial responders(14.8%) and null responders(30.3%). Overall, adverse events(AEs) occurred in 617 patients(73.9%) during the treatment. Anemia was the most frequent AE(52.9% of cases), especially in cirrhotic. The therapy was stopped for 14.6% of the patients because of adverse events or virological failure(15%). Sustained virological response was achieved in 62.7% of the cases, but was 43.8% in cirrhotic patients over 65 years of age. CONCLUSION: In everyday practice, triple therapy is safe but has moderate efficacy, especially for patients over 65 years of age, with advanced fibrosis, nonresponders to peginterferon + ribavirin.Antonio Ascione Luigi Elio Adinolfi Pietro Amoroso Angelo Andriulli Orlando Armignacco Tiziana Ascione Sergio Babudieri Giorgio Barbarini Michele Brogna Francesco Cesario Vincenzo Citro Ernesto Claar Raffaele Cozzolongo Giuseppe D’Adamo Emilio D’Amico Pellegrino Dattolo Massimo De Luca Vincenzo De Maria Massimo De Siena Giuseppe De Vita Antonio Di Giacomo Rosanna De Marco Giorgio De Stefano Giulio De Stefano Sebastiano Di Salvo Raffaele Di Sarno Nunzia Farella Laura Felicioni Basilio Fimiani Luca Fontanella Giuseppe Foti Caterina Furlan Francesca Giancotti Giancarlo Giolitto Tiziana Gravina Barbara Guerrera Roberto Gulminetti Angelo Iacobellis Michele Imparato Angelo Iodice Vincenzo Iovinella Antonio Izzi Alfonso Liberti Pietro Leo Gennaro Lettieri Ileana Luppino Aldo Marrone Ettore Mazzoni Vincenzo Messina Roberto Monarca Vincenzo Narciso Lorenzo Nosotti Adriano Maria Pellicelli Alessandro Perrella Guido Piai Antonio Picardi Paola Pierri Grazia Pietromatera Francesco Resta Luca Rinaldi Mario Romano Angelo Rossini Maurizio Russello Grazia Russo Rodolfo Sacco Vincenzo Sangiovanni Antonio Schiano Antonio Sciambra Gaetano Scifo Filomena Simeone Annarita Sullo Pierluigi Tarquini Paolo Tundo Alfredo Vallone 2016World Journal of Hepatology2016,8,22:1
5Direct Synthesis of N-methylurethanes from Primary Amines with Dimethyl Carbonate显示文摘Tundo Pietro Bressanello Salima Loris Alessandro 2005Pure and Applied Chemistry2005,77,10:1
6New developments in dimethyl carbonate chemistry 显示文摘Pietro Tundo 2001Pure and Applied Chemistry2001,73,7:1
7The chemistry of dimethyl carbonate显示文摘Pietro Tundo Maurizio Selva 2002Account of Chemical Research2002,35,9:1
8Selective hydrogenolysis of glycerol with raney nickel 显示文摘ANise Perosa Pietro Tundo 2005Ind Eng Chem Res2005,44,:1
9The Chemistry of Dimethyl Carbonate显示文摘Pietro Tundo Maurizio Selva 2002Accounts of Chemical Research2002,35,9:1
10Green organic syntheses: organic carbon- ates as methylating agents显示文摘Pietro Tundo Alvise Perosa 2002The Chemical Record2002,2,1:1
11Peptide anchored Langmuir-Blodgett films of a fullerence amphiphile显示文摘Pietro Tundo Alvise Perosa Maurizio Selva 2001Colloids and Surfaces2001,190,:1
12连续化气-液相转移催化合成法(Ⅰ)显示文摘气液相转移催化法(GL-PTC)是PTC(相转移催化法)的气相形式。气态反应物连续通过载有熔融的相转移催化剂的固体床,扩散到液层中,与活性的亲核试剂和(或)碱起反应,然后产物呈气态离开反应器。许多已知的能在PTC条件下进行的经典的有机合成反应(酯、烷基卤、醚、硫化物、丙二酸酯衍生物的合成等等),同样也可以用连续法在GL-PTC条件下进行。此外,在PTC条件下不能进行的合成反应,如碳酸二甲基酯(DMC)为试剂的反应,在GL—PTC中是安全的和高选择性的单烷基化试剂。DMC与酚反应生成苯甲醚,与苯胺反应生成单—N—甲基苯胺,与苯乙腈反应生成2—苯基丙腈。并且是真正的催化反应,因为固定床的组成没有改变,而甲醇和CO_2是此烷基化反应唯一的副产物。高选择性以及所处的特殊化学环境和相当高的温度,使得亲核试剂从进攻酰基碳(BAc2机理)转移到进攻DMC的烷基碳(BA12机理)。Pietro Tundo 黄艳刚 徐致 1991湖北化工1991,,2:0
13连续化气—液相转移催化合成法(续)显示文摘四、在中性和酸性介质中连续化过程 通过连续加入含有反应混合物与催化床的反应已实现〔方程(2)〕。根据不同的反应,催化剂可以改变,但在任何情况下,它都是负载在多孔的固体上的。有时,还需要有助催化剂,如在酸或碱性介质中进行的反应。通过反应平衡所形成的产物分配,其中一个可以完全地转化成产物。第一类例子是:在卤代烷中的卤素交换以及酯交换反应。第二种类型是有关异构化的反应,伯醇与盐酸反应(得到伯烷基卤)以及常见的二烷基碳酸酯的反应。Pietro Tundo 黄艳刚 徐玫 1991湖北化工1991,,3:0
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