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| 1 | Association of telomere length with authentic pluripotency of ES/iPS cells显示文摘Telomerase 和 telomeres 为干细胞的不定的复制是重要的。最近,体的房间的 telomeres 被发现是 reprogrammed 在导致的 pluripotent 干细胞(iPSCs ) 伸长。然而,在在胚胎的干细胞(转换字符) 或 iPSCs 的 vivo 的发展 pluripotency 的 telomeres 的角色直接没被探讨。我们证明有长 telomeres 的转换字符展出真发展 pluripotency,由完全的转换字符小狗以及 germline 能干的怪物的产生证实了在啮齿类动物可得到的最紧的测试。有短 telomeres 的转换字符显示出减少的 teratoma 形成和怪物生产,并且没能产生完全的转换字符小狗。Telomere 长度高度被相关(r > 0.8 ) 与转换字符的发展 pluripotency。短 telomeres 减少 proliferative 率或转换字符的能力,改变与 telomere epigenetics 有关的基因的表示,为 embryogenesis 重要的下面调整基因并且破坏细菌房间区别。而且,有更长的 telomeres 的 iPSCs 与短 telomeres 比那些与更高的效率产生怪物。我们功能的 telomeres 为 ESCs/iPSCs 的发展 pluripotency 是必要的并且建议那 telomere 长度可以提供一个珍贵标记评估干细胞 pluripotency 的数据表演,特别地当紧测试不是可行的时。 | Junjiu Huang Fang Wang Maja Okuka Na Liu Guangzhen Ji Xiaoying Ye Bingfeng Zuo Minshu Li Ping Liang William W Ge John CM Tsibris David L Keefe Lin Liu | 2011 | Cell Research2011，21，5： | 3 |
| 2 | IrrE, a global regulator of extreme radiation resistance inDeinococcus radiodurans, enhances salt tolerance in Escherichia coli and Brassica napus显示文摘 | Pan J Wang J Zhou Z Yan Y Zhang W Lu W Ping S Dai Q Yuan M Feng B Hou X Zhang Y Ma R Liu T Feng L Wang L Chen M Lin M | 2009 | PloS One2009，4，2： | 1 |
| 3 | Chloroquine protects mice from challenge with CpG ODN and LPS by decreasing proinflammatory cytokine release显示文摘 | Hong Z Jiang Z Liangxi W Guofu D Ping L Yongling L | 2004 | Int Immunopharmacol2004，4，： | 1 |
| 4 | Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme显示文摘 | Ping Z l iu W Kang Z | 2010 | Brain Res2010，1343，： | 1 |
| 5 | Assessment of uterine receptivity by the endomctrial - subendometrial blood flow distribution pattern in women undergoing in vitro fertilization - embryo transfer 显示文摘 | Chien L W Au H K Chen Ping - ling | 2002 | Fertility and Sterility2002，78，2： | 1 |
| 6 | Dexmedetomidine pharmacodynamics : Part II : Crossover comparison of the analgesic effect of dexmedetomidine and remifentanil in healthy volunteers 显示文摘 | CORTINEZ L I HSU Y W SUM - PING S T | 2004 | Anesthesiology2004，101，5： | 1 |
| 7 | Three-Dimensional Visualization Technology and Therapy Planning System for Microwave Ablation Therapy of Liver Tumor 显示文摘 | Jin X Wen B W Ping L | 2015 | Springer Netherlands2015，，： | 1 |
| 8 | Dispersion and alignment of carbon nanotubes in polymer matrix: a review显示文摘 | Xie X L Mai Y W Ping X | 2005 | Mater Sci Eng R: Reports2005，49，： | 1 |
| 9 | Balanced recipro- cal translocations detected at amniocentesis original research article 显示文摘 | Chih -Ping C Pei -Chen W Chen- Ju L | 2010 | Taiwanese Journal of Obstetrics and Gynecology2010，4，49： | 1 |
| 10 | Chloroquine protects mice from challenge with CpG ODN and LPS by decreasing proinflammatory cytokine release显示文摘 | Hong Z Jiang Z Liangxi W Guofu D Ping L Yongling L | 2004 | Int Immunopharmacol2004，4，： | 1 |
| 11 | Modulation of Ca^2+/calmod- ulin-dependent protein kinase II activity by acute and chronic morphine administration in rat hippocampus : differential regulation of α and β isoforms显示文摘 | Liguang L Tianhua Z Ping W | 1999 | Mol Pharmaeol1999，5，： | 1 |
| 12 | Interleaving-based multiple access and iterative chip-by-chip muhiuser detection 显示文摘 | Leung W K Liu L H Li Ping | 2003 | IEICE Transactions on Communications2003，86，12： | 1 |
| 13 | Sulforaphane protects brains against hypoxle-ischemic injury through induction of Nrf2-dependent phase 2 enzyme显示文摘 | Ping Z l lu W Kang Z | 2010 | Brain Res2010，1343，1： | 1 |
| 14 | Protein separation using free-flow electrophoresis microchip etched in a single step 显示文摘 | Ping L W Li H Z Yu K Z | 2010 | J Sep Sci2010，33，： | 1 |
| 15 | Decoding low density parity check codes with finite quantization bits显示文摘 | PING L LEUNG W K | 2000 | Communications Letters IEEE2000，4，2： | 1 |
| 16 | Photodegradation of mefenamic acid in aqueous media: Kinetics, toxicity and photolysis products 显示文摘 | PING C FENG L W YAO K | 2015 | Bulletin of Environmental Contamination & Toxicology2015，96，2： | 1 |
| 17 | Increased depression and read- mission risk in patients with new-onset angina after the Sichuan earthquake 显示文摘 | Kai-Sen H Qi W Ping L | 2011 | Prehosp Disaster Med Earthquake2011，26，： | 1 |
| 18 | Effects of organic matter heterogeneity on sorption and desorption of organic contaminants by soils and sediments显示文摘 | Huang W L Ping P A Yu Z Q | 2003 | Applied Geochemistry2003，18，7： | 1 |
| 19 | Sensitive and rapid method to quantify icaritin and desmethylicaritin in human serum using gas chromatography-mass spect-rometry显示文摘 | Shen Ping Shih P W Yong E L | 2007 | Journal of Chromatography B2007，857，： | 1 |
| 20 | An Inner Cur-rent Suppressing Method for Modular Multilevel Convert-ers显示文摘 | ZIXIN L PING W ZUNFANG C | 2013 | Power Electronics2013，28，11： | 1 |
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