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| 1 | A sex-chromosome anomaly in a case of gonadal dysgenesis( Tumer's syndrome) 显示文摘 | Ford CE Jones KW Polani PE | 1959 | Lancet1959，1，7075： | 1 |
| 2 | Modeling Human- induced climate change:a summary for environmental managers 显示文摘 | Sulzlman E W Polani K A Kittel T G | 1995 | Environmental Management1995，19，2： | 1 |
| 3 | Centromere localization at meiosis and the position of chiasmata in the male and female mouse显示文摘 | P. E. Polani | 1972 | Chromosoma1972，，4： | 1 |
| 4 | Hyperoxia - induced changes in hu- man airway epithelial cells:The protective effect perflubron显示文摘 | Polani B Aaron C Thomas HS | 2005 | Pedi- atr Crit Care Med2005，6，： | 1 |
| 5 | A sex-chromosome anomaly in a case of gonadal dysgenesis (Turner's syndrome)显示文摘 | Ford CE Jones KW Polani PE | | 0，，7075： | 1 |
| 6 | The logic of tacit inference 显示文摘 | POLANY IM | 1966 | Philosophy1966，41，1： | 1 |
| 7 | Information flows in causal networks显示文摘 | Ay N Polani D | 2008 | Advances in Complex Systems2008，11，1： | 1 |
| 8 | Personal Knowledge显示文摘 | Polani M | 1958 | Chicago:University of Chicago Press1958，，： | 1 |
| 9 | A sex-chromosome anomaly in a case of gonadal dysgenesis(Turner's syndrome)显示文摘 | Ford C E Jones K W Polani P E | 1959 | Lancet1959，1，7075： | 1 |
| 10 | Stroma-targeting strategies in pancreatic cancer:Past lessons,challenges and prospects显示文摘Pancreatic ductal adenocarcinoma(PDAC)is projected to emerge as the second leading cause of cancer-related death after 2030.Extreme treatment resistance is perhaps the most significant factor that underlies the poor prognosis of PDAC.To date,combination chemotherapy remains the mainstay of treatment for most PDAC patients.Compared to other cancer types,treatment response of PDAC tumors to similar chemotherapy regimens is clearly much lower and shorterlived.Aside from typically harboring genetic alterations that to date remain undruggable and are drivers of treatment resistance,PDAC tumors are uniquely characterized by a densely fibrotic stroma that has well-established roles in promoting cancer progression and treatment resistance.However,emerging evidence also suggests that indiscriminate targeting and near complete depletion of stroma may promote PDAC aggressiveness and lead to detrimental outcomes.These conflicting results undoubtedly warrant the need for a more in-depth understanding of the heterogeneity of tumor stroma in order to develop modulatory strategies in favor of tumor suppression.The advent of novel techniques including single cell RNA sequencing and multiplex immunohistochemistry have further illuminated the complex heterogeneity of tumor cells,stromal fibroblasts,and immune cells.This new knowledge is instrumental for development of more refined therapeutic strategies that can ultimately defeat this disease.Here,we provide a concise review on lessons learned from past stromatargeting strategies,new challenges revealed from recent preclinical and clinical studies,as well as new prospects in the treatment of PDAC. | Faran Polani Patrick M Grierson Kian-Huat Lim | 2021 | World Journal of Gastroenterology2021，27，18： | 1 |
| 11 | Sequential learning with LS-SVMfor large-scale data sets 显示文摘 | JUNG T POLANI D | 2006 | Lecture Notes in ComputerScience2006，4132，： | 1 |
| 12 | Regulation of apical surface fluid and protein secretion in human airway epithelial cell line Calu-3 显示文摘 | POLANI B RAMESH B AARON C | 2004 | Biochem Biopbys Res Commun2004，319，： | 1 |
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