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9篇 您的检索式：作者名="Pollok E"

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		题名	作者	年代	出处	被引量
	1	PET imaging and optical imaging with D-lueiferin methyl es- ter and D-luciferin methyl ether of luciferase gene expression in tumor xenografts of living mice 显示文摘	Wang J-Q Pollok K E Cai S	2006	Bioorganic & Medicinal Chemistry Letters2006，16，2：	1
	2	Peptidomies of identified neurons demonstrates a highly differentiated expression pattern of FXPRLamides in the neureendoerine system of an insect显示文摘	Predel R Eckert M Pollok E	2007	J Comp Neurol2007，500，3：	1
	3	A theoretically optimized method for cord blood stem cell cryopreservation显示文摘	Woods E J Liu J Pollok K	2003	J of Hemato and Stem Cell Res2003，12，：	1
	4	Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum 显示文摘	Agranoff D Fernandez-Reyes D Papadopoulos MC Rojas SA Herbster M Loosemore A Tarelli E Sheldon J Schwenk A Pollok R Rayner CF Krishna S	2006	Lancet2006，368，：	1
	5	Potential role of 4 - 1 BB in T cell activation Comparison with the costimulatory molecule CD28 显示文摘	HURTADO J C KIM S H POLLOK K E	1995	J Imuunol1995，155，7：	1
	6	Targeting the anti-apoptotie protein c-FLIP for cancer therapy 显示文摘	Safa A R Pollok K E	2011	Cancers2011，3，2：	1
	7	Influ- ence of microorganisms on biotite dissolution:An experimen- tal approach 显示文摘	Hopf J Langenhorst F Pollok K Merten D Kothe E	2008	Chemic der Erde2008，69，2：	1
	8	Nitric oxide synthesis characteration purification,molecular cloning and functions显示文摘	FORSTERMAN U CLOSS E I POLLOK J S et a1	1994	Hypertension1994，23，：	1
	9	How old is too old? In vivo engraftment of human peripheral blood stem cells cryopreserved for up to 18 years-implications for clinical transplantation and stability programs显示文摘BACKGROUND Peripheral blood stem cells(PBSC)are commonly cryopreserved awaiting clinical use for hematopoietic stem cell transplant.Long term cryopreservation is commonly defined as five years or longer,and limited data exists regarding how long PBSC can be cryopreserved and retain the ability to successfully engraft.Clinical programs,stem cell banks,and regulatory and accrediting agencies interested in product stability would benefit from such data.Thus,we assessed recovery and colony forming ability of PBSC following long-term cryopreservation as well as their ability to engraft in NOD/SCID/IL-2 Rγnull(NSG)mice.AIM To investigate the in vivo engraftment potential of long-term cryopreserved PBSC units.METHODS PBSC units which were collected and frozen using validated clinical protocols were obtained for research use from the Cellular Therapy Laboratory at Indiana University Health.These units were thawed in the Cellular Therapy Laboratory using clinical standards of practice,and the pre-freeze and post-thaw characteristics of the units were compared.Progenitor function was assessed using standard colony-forming assays.CD34-selected cells were transplanted into immunodeficient mice to assess stem cell function.RESULTS Ten PBSC units with mean of 17 years in cryopreservation(range 13.6-18.3 years)demonstrated a mean total cell recovery of 88%±12%(range 68%-110%)and post-thaw viability of 69%±17%(range 34%-86%).BFU-E growth was shown in 9 of 10 units and CFU-GM growth in 7 of 10 units post-thaw.Immunodeficient mice were transplanted with CD34-selected cells from four randomly chosen PBSC units.All mice demonstrated long-term engraftment at 12 wk with mean34%±24%human CD45+cells,and differentiation with presence of human CD19+,CD3+and CD33+cells.Harvested bone marrow from all mice demonstrated growth of erythroid and myeloid colonies.CONCLUSION We demonstrated engraftment of clinically-collected and thawed PBSC following cryopreservation up to 18 years in NSG mice,signifying likely successful clinical transplantation of PBSC following long-term cryopreservation.	John Underwood Mahvish Rahim Carijo West Rebecca Britton Elaine Skipworth Vicki Graves Steven Sexton Hillary Harris Dave Schwering Anthony Sinn Karen E Pollok Kent A Robertson W Scott Goebel Kerry M Hege	2020	World Journal of Stem Cells2020，12，5：	0

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