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| 1 | 东方蜜蜂高效的卫生行为机制对于西方蜜蜂抗病育种的启示显示文摘西方蜜蜂(Apismellifera)在世界各地大范围的蜂群损失现象已引起科学界和公众的广泛关注,其健康状况与东方蜜蜂(Apis cerana)相比明显较劣。东方蜜蜂群内可检测到的病原体和寄生虫相对较少,即它们对于生物威胁具有更强的抵抗力,即便是面对异种入侵的新病原(如蜜蜂残翅病毒)。 | Lin Z Page P Li L Qin Y Zhang Y Hu F Neumann P Zheng H Dietemann V 蔺哲广 郑火青 胡福良 | 2016 | 中国蜂业2016，67，12： | 5 |
| 2 | 油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%. | 刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F | 2021 | 中华高血压杂志2021，29，2： | 3 |
| 3 | Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer. | Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 3 |
| 4 | An ionic liquid coating for determination of sildenafil and UK-103,320 in human serum by capillary zone electrophoresis-ion trap mass spectrometry显示文摘 | Qin Weidong Li Sam F Y | 2002 | Electrophoresis2002，23，24： | 1 |
| 5 | Vibration characteristics of rotating thin cylindrical shells for various boundary conditions显示文摘 | Liu Y Q Qin Z Y Chu F L | 2012 | J Tsinghua Univ (Sci & Tech)2012，52，1： | 1 |
| 6 | Surveys of transmitted HIV drug resistance in 7 geographic regions in China, 2008-2009 显示文摘 | Liao L Xing H Dong Y Qin G Ma Y Lu H Chen L Zhang L Osborne C Seguy N Wei D Sun F Yang J Ru- an Y Shao Y | 2012 | Clin Infect Dis2012，54，4： | 1 |
| 7 | An Iterative Method of Solution for Equilibrium and Optimization Problems显示文摘 | SU Y F SHANG M J QIN X L | 2008 | Nonlinear Anal2008，64，： | 1 |
| 8 | An accurate nonlinear QSAR model for the antitumor activities of chloroethylnitrosoureas u- sing neural networks显示文摘 | Qin Y Deng H F Yan H | 2011 | Journal of Molecualr Graphics and Modelling2011，29，6： | 1 |
| 9 | Finite element analysis of the clamp band joint 显示文摘 | QIN Z Y YAN S Z CHU F L | 2012 | Applied Mathematical Modelling2012，36，1： | 1 |
| 10 | Research on iterated Hilbert transform and its application in mechanical fault diagnosis显示文摘 | Qin Y Qin S R Mao Y F | | 0，，08： | 1 |
| 11 | Relationship between haemolytic and adjuvant activity and structure of protopanaxadiol- type saponins from the roots of Panax notoginseng 显示文摘 | Sun H X Qin F Ye Y P | 2005 | Vaccine2005，，23： | 1 |
| 12 | Thermodynamic processes and phenomena induced by high current pulsed electron beam显示文摘 | Qin Y Song Z F Dong C | | 0，，561： | 1 |
| 13 | Inverted Nano- taper-based Ag Film for Optical Absorption and SERS Applications显示文摘 | YANG C Y QIN Y ZHU X F et a | 2015 | Journal of Alloys and Com- pounds2015，632，： | 1 |
| 14 | TLR3signaling in macrophages is indispensable for the protective immunity of invariant natural killer T cells against enterovirus 71infection显示文摘 | Zhu K Yang J Luo K Yang C Zhang N Xu R Chen J Jin M Xu B Guo N Wang J Chen Z Cui Y Zhao H Wang Y Deng C Bai L Ge B Qin C F Shen H Yang C F Leng Q | 2015 | PLoS Pathog2015，11，10： | 1 |
| 15 | A Class of Filled Functions for Finding a Global Minimizer of a Function of Several Variables显示文摘 | Ge R P Qin Y F | 1987 | Journal of Optimization Theory and Applications1987，54，2： | 1 |
| 16 | cDNA cloning and SSCP analysis on Ss5MaT1gene in Salvia splendens显示文摘 | Li F L Qin F F Feng Y Z | 2009 | Journal of Food Agriculture&Environment2009，7，2： | 1 |
| 17 | S100A8/A9 induces apoptosis and in- hibits metastasis of CasKi human cervical cancer cells 显示文摘 | Qin F Song Y Li Z | 2010 | Pathol Oncol Res2010，16，3： | 1 |
| 18 | Investigation of glucose-modi- fied liposomes using polyethylene glycols with different chain lengths as the linkers for brain targeting显示文摘 | Xie F L Yao N Qin Y | 2012 | Int J Nanomedi- cine2012，7，2： | 1 |
| 19 | Particle-epithelial interaction:effect ofpriming and bystander neutrophils on interleuin-8 release显示文摘 | Ning Y Tao F Qin G | 2004 | Am JRespir Cell Mol Biol2004，30，： | 1 |
| 20 | In situ XAS study on the mechanism of reactive adsorption desulfurization of oil product over Ni/ZnO显示文摘 | HUANG L C WANG G F QIN Z F DONG M DU M X GE H LI X K ZHAO Y D ZHANG J HU T D WANG J G | 2011 | Appl Catal B: Environ2011，106，12： | 1 |
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