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| 1 | Systematic review and meta-analysis on the association of tuberculosis in Crohn's disease patients treated with tumor necrosis factor-α inhibitors(Anti-TNFα)显示文摘AIM To perform a meta-analysis on the risk of developing Mycobacterium tuberculosis(TB) infection in Crohn's disease(CD) patients treated with tumor necrosis factoralpha(TNFα) inhibitors.METHODS A meta-analysis of randomized, double-blind, placebocontrolled trials of TNFα inhibitors for treatment of CD in adults was conducted. Arcsine transformation of TB incidence was performed to estimate risk difference. A novel epidemiologically-based correction(EBC) enabling inclusions of studies reporting no TB infection cases in placebo and treatment groups was developed to estimate relative odds.RESULTS Twenty-three clinical trial studies were identified, including 5669 patients. Six TB infection cases were reported across 5 studies, all from patients receiving TNFα inhibitors. Eighteen studies reported no TB infection cases in placebo and TNFα inhibitor treatment arms. TB infection risk was significantly increased among patients receiving TNFα inhibitors, with a risk difference of 0.028(95%CI: 0.0011-0.055). The odds ratio was 4.85(95%CI: 1.02-22.99) with EBC and 5.85(95%CI: 1.13-30.38) without EBC.CONCLUSION The risk of TB infection is higher among CD patients receiving TNFα inhibitors. Understanding the immunopathogenesis of CD is crucial, since using TNFα inhibitors in these patients could favor mycobacterial infections, particularly Mycobacterium avium subspecies paratuberculosis, which ultimately could worsen their clinical condition. | Brent L Cao Ahmad Qasem Robert C Sharp Latifa S Abdelli Saleh A Naser | 2018 | World Journal of Gastroenterology2018，24，25： | 4 |
| 2 | A study of in vitro antibacterial activity of lanthanides complexes with a tetradentate Schiff base ligand显示文摘Objective:To establish the antibacterial activity of lanthanides complexes with a tetradentate Schiff base ligand L.Methods:(N,N'-bis(l-naphthaldimine)-o-phenylenediamine)was prepared from the condensation of 2—hydroxy-1-naphthaldehyde with o-phenylenediamine in a molar ratio of 2:1.The antimicrobial activity of the resultant Ln(Ⅲ)complexes was investigated using agar well diffusion and micro-broth dilution techniques;the latter was used to establish the minimum inhibitory concentrations for each compound investigated.Results:Most of Ln(Ⅲ)complexes were found to exhibit antibacterial activities against a number of pathogenic bacteria with MICs ranging between 1.95-250.00μg/mL.Staphylococcus aureus was the most susceptible bacterial species to[LaL(NO_3)_2(H_2O)](NO_3)complex while Shigella dysenteriae and Escherichia coli required a relatively higher MIC(250μg/mL).Trie complexes La(Ⅲ)and Pr(Ⅲ)were effective inhibitors against Staphylococcus aureus,whereas Sm(Ⅲ)complex was effective against Serratia marcescens.On the other hand,Gd(Ⅲ),La(Ⅲ)and Nd(Ⅲ)were found to be more potent inhibitors against Pseudompnas aeruginosa than two of commonly used antibiotics.The remaining Ln(Ⅲ)complexes showed no remarkable activity as compared to the two standard drugs used.Conclusions:Tetradentate Schiff base ligand L and its complexes could be a potential antibacterial compounds after further investigation. | Waleed Mahmoud Al Momani Ziyad Ahmed Taha Abdulaziz Mahmoud Ajlouni Qasem Mohammad Abu Shaqra Muaz Al Zouby | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，5： | 3 |
| 3 | Knowledge,attitude,and practices related to cutaneous leishmaniasis in an endemic focus of cutaneous leishmaniasis,Southern Iran显示文摘Objective:To assess knowledge,attitudes,and practices(KAP)of inhabitants of an endemic area it)Fars province toward cutaneous leishmaniasis(CI).Methods:the study was carried out in Lapui district in Fars province,south of Iran,one of the most important foci of CL in this province.Sample size(237 residents)was calculated based on population.House-to-house survey was done to collect the data regarding knowledge,attitudes,and practices of the inhabitants.The head of each household was interviewed by a trained staff to assess his/her KAP related to CL.A semi-structured KAP questionnaire was used for data collection.Results:Mean age of participants was 39 and more titan half of the respondents were in the age group of 31-40.Males constituted 172(72.5%)of subjects.Most of the respondents(84.3%)were literate.The majority of the study poulation(83%)had heard about SalaJc(local name for CL)and most of these respondents(91%)were aware that CL is presented with a cutaneous lesion.Nearly two-third of the participants(63.5%)stated the bite of mosquito(not specifically sandflies)for CL transmission.The respondents'attitude regarding the treatment of CL was not satisfactory since Only 48%believed that CL can be treated by medicine.A noticeable proportion of respondents(21%)believed in indigenous medicine for the treatment of CL.A small proportion of respondents(14%)stated that traditional healers are good at treating this disease.More than two-third(69%)of respondents believed that the disease is preventable although most of interviewees did not know about preventive measures.Conclusions:In this study,insufficient knowledge of community about infection nature,vector,transmission mode and preventive measures of CL,highlights the needs for a health education initiative to enhance the awareness of people about CL.This would improve inhabitants'contribution in control program of CL in this area. | Bahador Sarkari Asgari Qasem Mohammad Reza Shafaf | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，7： | 2 |
| 4 | 石榴皮多酚的抑菌活性及其在鲜牛乳储藏中的应用显示文摘本文就不同品种的石榴皮多酚的提取物进行了研究。测定了来源于中国、也门及突尼斯的的石榴皮中的总酚含量、水合单宁及总黄酮含量。50%甲醇提取的石榴皮提取物含有最高的生物活性物质,并且具有最好的抑制单增李斯特菌、沙门氏菌、嗜热链球菌及大肠杆菌的活性。将此高活性的石榴皮提取物用于鲜牛乳的保藏实验,有效地使得鲜牛乳保持了较好的原有风味。此外。石榴皮提取物的加入显著地降低了鲜牛乳的pH值,增加了其可滴定酸度,并同时降低了牛乳中的总菌数。以上的结果表明:石榴皮提取物可作为一种潜在的天然防腐剂用于鲜牛乳的保藏。 | 宋微 Ahmed Mahyoub Qasem 韩雪 迟淳良 曲宜 刘辉 张兰威 | 2015 | 中国甜菜糖业2015，0，2： | 2 |
| 5 | An Ensemble Learning Based Approach for Detecting and Tracking COVID19 Rumors显示文摘Rumors regarding epidemic diseases such as COVID 19,medicines and treatments,diagnostic methods and public emergencies can have harmful impacts on health and political,social and other aspects of people’s lives,especially during emergency situations and health crises.With huge amounts of content being posted to social media every second during these situations,it becomes very difficult to detect fake news(rumors)that poses threats to the stability and sustainability of the healthcare sector.A rumor is defined as a statement for which truthfulness has not been verified.During COVID 19,people found difficulty in obtaining the most truthful news easily because of the huge amount of unverified information on social media.Several methods have been applied for detecting rumors and tracking their sources for COVID 19-related information.However,very few studies have been conducted for this purpose for the Arabic language,which has unique characteristics.Therefore,this paper proposes a comprehensive approach which includes two phases:detection and tracking.In the detection phase of the study carried out,several standalone and ensemble machine learning methods were applied on the Arcov-19 dataset.A new detection model was used which combined two models:The Genetic Algorithm Based Support Vector Machine(that works on users’and tweets’features)and the stacking ensemble method(that works on tweets’texts).In the tracking phase,several similarity-based techniques were used to obtain the top 1%of similar tweets to a target tweet/post,which helped to find the source of the rumors.The experiments showed interesting results in terms of accuracy,precision,recall and F1-Score for rumor detection(the accuracy reached 92.63%),and showed interesting findings in the tracking phase,in terms of ROUGE L precision,recall and F1-Score for similarity techniques. | Sultan Noman Qasem Mohammed Al-Sarem Faisal Saeed | 2022 | Computers, Materials & Continua2022，，1： | 2 |
| 6 | On-chip micro-electromagnets for magnetic-based bio-molecules separation显示文摘 | Qasem Ramadan Victor Samper Daniel Poenar Chen Yu | 2004 | Journal of Magnetism and Magnetic Materials2004，，2： | 1 |
| 7 | Indicators of biofilm development and activity in constructed wetlands microcosms显示文摘 | Ragusa S R McNevin D Qasem S | 2004 | Water Research2004，38，： | 1 |
| 8 | Radial basis function network based on time variantmulti-objective particle swarm optimization for medical diseasesdiagnosis显示文摘 | Qasem S N Shamsuddin S M | 2011 | Applied Soft Computing2011，11，1： | 1 |
| 9 | Dust‐induced shading on photovoltaic modules显示文摘 | Hassan Qasem Thomas R. Betts Harald Müllejans Hassan AlBusairi Ralph Gottschalg | 2014 | Prog. Photovolt: Res. Appl2014，，： | 1 |
| 10 | Descending necrotising mediastinitis, a fatal disease to keep in mind 显示文摘 | Abu Abeeleh M A1 Smady M Qasem H | 2010 | Heart Lung Circ2010，19，4： | 1 |
| 11 | Meteorological factors, aeroallergens and asthma-related visits in Kuwait: a 12-month retrospective study 显示文摘 | Qasem J A Nasrallah H A1-Khalaf B N | 2008 | Ann Saudi Med2008，28，： | 1 |
| 12 | Nitric: oxide regulates local arterial distensibility in vivo显示文摘 | Wilkinson B Qasem A McEniery M | 2002 | Circulation2002，105，2： | 1 |
| 13 | Fungicidal activity of some common weed extracts against different plant pathogenic fungi 显示文摘 | Qasem J R Abu-blan H A | 1996 | Journal of Phytopathology1996，144，： | 1 |
| 14 | Antifungal activity of aqueous extracts from some common weed species显示文摘 | Qasem J R Abu-blan H A | 1995 | Annuals of Applied Biology1995，127，1： | 1 |
| 15 | Susceptibility ofsome bacterial contaminants recovered from commercial cosm-etics in Jordan to preservatives and antibiotics 显示文摘 | Qasem MAS Walid AI-Momani Rania MAG | 2014 | TropicalJournal of Pharmaceutical Research2014，13，2： | 1 |
| 16 | Loading magnetic nanoparticles into sperm cells does not affect their functionality显示文摘 | Makhluf S B D Qasem R Rubinstein S | 2006 | Langmuir2006，22，94： | 1 |
| 17 | Allelopathic potential of white top and syrian sage on vegetable crops显示文摘 | Qasem J R | 2001 | Agronomy Journal2001，93，1： | 1 |
| 18 | Multi-objective hybrid evolutionary algorithms for radial basis function neural network design 显示文摘 | QASEM S N SHAMSUDD1N S M ZAIN A M | 2012 | Knowledge-Based Systems2012，27，1： | 1 |
| 19 | Endothelin-1 regulates arterial pulse wave velocity in vivo 显示文摘 | McEniery C M Qasem A Schmitt M | 2003 | J Am Coll Cardiol2003，42，11： | 1 |
| 20 | Meteorological factors,aeroallergens and asthma-related visits in Kuwait :a 12 month retrospective sludy显示文摘 | Qasem J A Nasrallah H AI khalaf B N | 2008 | Ann Saudi Med2008，28，6： | 1 |
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