| 1 | Ground-Based Atmospheric CO_(2),CH_(4),and CO Column Measurements at Golmud in the Qinghai-Tibetan Plateau and Comparisons with TROPOMI/S5P Satellite Observations显示文摘Measurements of carbon dioxide(CO_(2)),methane(CH_(4)),and carbon monoxide(CO)are of great importance in the Qinghai-Tibetan region,as it is the highest and largest plateau in the world affecting global weather and climate systems.In this study,for the first time,we present CO_(2),CH_(4),and CO column measurements carried out by a Bruker EM27/SUN Fourier-transform infrared spectrometer(FTIR)at Golmud(36.42°E,94.91°N,2808 m)in August 2021.The mean and standard deviation of the column-average dry-air mixing ratio of CO_(2),CH_(4),and CO(XCO_(2),XCH_(4),and XCO)are 409.3±0.4 ppm,1905.5±19.4 ppb,and 103.1±7.7 ppb,respectively.The differences between the FTIR co-located TROPOMI/S5P satellite measurements at Golmud are 0.68±0.64%(13.1±12.2 ppb)for XCH_(4) and 9.81±3.48%(–10.7±3.8 ppb)for XCO,which are within their retrieval uncertainties.High correlations for both XCH_(4) and XCO are observed between the FTIR and S5P satellite measurements.Using the FLEXPART model and satellite measurements,we find that enhanced CH_(4) and CO columns in Golmud are affected by anthropogenic emissions transported from North India.This study provides an insight into the variations of the CO_(2),CH_(4),and CO columns in the Qinghai-Tibetan Plateau. | Minqiang ZHOU Qichen NI Zhaonan CAI Bavo LANGEROCK Jingyi JIANG Ke CHE Jiaxin WANG Weidong NAN Yi LIU Pucai WANG | 2023 | Advances in Atmospheric Sciences2023，40，2： | 1 |
| 2 | Exposure to jet lag aggravates depression-like behaviors and age-related phenotypes in rats subject to chronic corticosterone显示文摘Our previous finding demonstrated that chronic corticosterone(CORT)may be involved in mediating the pathophysiology of premature aging in rats.Frequent jet lag increases the risk for many diseases,including obesity and type 2 diabetes,and is associated with the aging processes.However,the effect of jet lag on CORT-induced depression and its association with aging phenotypes remain unclear.In this study,the rats were exposed to both CORT and jet lag treatment,and the differences were analyzed and compared to rats with single CORT treatment.Our results showed that jet lag treatment aggravated CORT-induced depression-like behavior evidenced by sucrose intake test,forced swimming test,and open field test.Additionally,this treatment aggravated the shortening of telomeres,which possibly resulted in decreased telomerase activity,and downregulated the expression of telomere-binding factor 2(TRF2)and telomerase reverse transcriptase compared to that in CORT rats,as revealed by quantitative real-time-polymerase chain reaction and western blot analysis,respectively.The shortening of telomeres may have been caused by increased oxidative stress,which was associated with the inhibition of sirtuin 3.Exposure to jet lag also aggravated the degeneration of mitochondrial functions,as shown by the decreases in the mRNA expression of COX1,ND1,and Tfam.Our findings provide physiological evidence that jet lag exposure may worsen stress-induced depression and age-related abnormalities. | Qichen Shen Junli Wu Yuehan Ni Xiaoxian Xie Chunan Yu Qingfeng Xiao Jiafeng Zhou Xia Wang Zhengwei Fu | 2019 | Acta Biochimica et Biophysica Sinica2019，51，8： | 0 |
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