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| 1 | A high-resolution climatic change since Holocene inferred from multi-proxy of lake sediment in westerly area of China显示文摘Multi-proxy data are presented and a discuss is made of paleoclimatic and paleoenvironmental changes during Holocene from a 225-cm-long sediment core from Wulungu Lake, located in westerly area of China. The chronology is constructed from six AMS radiocarbon dates on the bulk organic matter. Analyses of pollen, TOC, TN, δ 13Corg, ostracod assemblages and the shell stable isotopes, suggest Holocene climate pattern as follows: temperate and dry (10.0―7.6 cal. ka BP)-warm and wet (7.6―5.3 cal. ka BP) -warm and moist (5.3―3.6 cal. ka BP) -temperate and dry (3.6―2.1 cal. ka BP)-temperate and moist (2.1―1.3 cal. ka BP) -cool and dry (1.3 cal. ka BP―present). With the climatic change, Wulungu Lake experienced two large-scale retreat (5.3―3.6 cal. ka BP and 1.3 cal. ka BP―present) and an obvious transgression (7.6―5.3 cal. ka BP). The records of climatic and environmental evolution of Wulungu Lake were in good accordance with those of adjacent areas. It responded to regional environmental change, global abrupt climate events and followed the westerly climate change mode. | JIANG QingFeng SHEN Ji LIU XingQi ZHANG EnLou XIAO XiaYun | 2007 | Chinese Science Bulletin2007，52，14： | 28 |
| 2 | Environmental changes during early-middle Holocene from the sediment record of the Chaohu Lake,Anhui Province显示文摘A typical lake sediment core is obtained from the Chaohu Lake in the lower reaches of the Yangtze River,Anhui Province,China.The timing scale is constrained by AMS 14 C dating method.Climate proxies such as pollen and grain size in the core are analyzed to reconstruct the environment changes at this site approximately between 9870 and 2170 cal.a BP.The results indicate that at the research area, the climate in the early-middle Holocene had evolved through 3 stages.From 9870 to 6040 cal.a BP, proxy records show a warm and dry climate with low water levels after the late-glacial period.During this stage,cool and dry events occurred at about 8910 and 6060-6030 cal.a BP.Then,between 6040 and 4860 cal.a BP,the climate was humid and vegetation was more flourishing in the Chaohu Lake Valley.The Holocene Optimum occurred at 5840-5500 cal.a BP in the Chaohu Lake,showing the best condition of water and heat.Elm Decline occurred at the period of 5380-4930 cal.a BP.Since 4860 cal.a BP,the climate was warm and dry through 2170 cal.a BP as shown in both pollen spectrum and grain-size histories.Two obvious dry events occurred in 3760 and 2170 cal.a BP,respectively.At 2170 cal.a BP,the water level of the Chaohu Lake reached the lowest as the lakebed possibly exposed. Such lake sediment observations are consistent with the historical records in this area. | XinYuan Wang GuangSheng Zhang Li Wu XiHui Zhang EnLou Zhang XiaYun Xiao QingFeng Jiang | 2008 | Chinese Science Bulletin2008，53，S1： | 15 |
| 3 | A group of SUVH methyl-DNA binding proteins regulate expression of the DNA demethylase ROS_1 in Arabidopsis显示文摘DNA methylation is typically regarded as a repressive epigenetic marker for gene expression.Genome-wide DNA methylation patterns in plants are dynamically regulated by the opposing activities of DNA methylation and demethylation reactions. In Arabidopsis, a DNA methylation monitoring sequence(MEMS) in the promoter of the DNA demethylase gene ROS_1 functions as a methylstat that senses these opposing activities and regulates genome DNA methylation levels by adjusting ROS_1 expression. How DNA methylation in the MEMS region promotes ROS_1 expression is not known. Here, we show that several Su(var)3-9 homologs(SUVHs) can sense DNA methylation levels at the MEMS region and function redundantly to promote ROS_1 expression. The SUVHs bind to the MEMS region, and the extent of binding is correlated with the methylation level of the MEMS.Mutations in the SUVHs lead to decreased ROS_1 expression, causing DNA hypermethylation at more than 1,000 genomic regions. Thus, the SUVHs function to mediate the activation of gene transcription by DNA methylation. | Xinlong Xiao Jieqiong Zhang Tao Li Xing Fu Viswanathan Satheesh Qingfeng Niu Zhaobo Lang Jian-Kang Zhu Mingguang Lei | 2019 | Journal of Integrative Plant Biology2019，61，2： | 11 |
| 4 | The chimeric genes in the hybrid lineage of Carassius auratus cuvieri(♀)×Carassius auratus red var.(♂)显示文摘Hybridization can combine the genomes of different strains or species, which leads to changes of genotype and phenotype in the hybrids. In this study, we aimed to investigate the genetic variations of hybrids(WR-F1 and WR-F2) derived from the intraspecific hybridization of white crucian carp(Carassius auratus cuvieri, WCC, ♀) and red crucian carp(Carassius auratus red var., RCC, ♂). Here, we compared the orthologous genes in the liver transcriptomes of hybrids with those of WCC and RCC, and classified the orthologous genes into eight gene patterns within three categories(chimera, mutant, and biparental origin genes).The results revealed 19.04%, 4.17% chimeric genes and 6.90%, 5.05% mutations of orthologous genes in WR-F1 and WR-F2 respectively. Seventeen of twenty-three characterized genes(77%) were confirmed to be the chimeras at the genomic DNA level.The GO classification discovered that some chimeric and mutant genes were related to metabolic process, immune system and developmental process in WR-F1. Our results provide the new evidence that hybridization can combine the parental genomes,leading to changes in the genotype of the resultant hybrids. This is the first report on the formation of chimeric genes from fish intraspecific hybridization, which is potentially interesting from the context of both evolution and the genetic breeding of fish. | Qingfeng Liu Yanhua Qi Qiuli Liang Xiujuan Xu Fangzhou Hu Jing Wang Jun Xiao Shi Wang Wuhui Li Min Tao Qinbo Qin Rurong Zhao Zhanzhou Yao Shaojun Liu | 2018 | Science China(Life Sciences)2018，61，9： | 6 |
| 5 | Single W18O49 nanowires: A multifunctional nanoplatform for computed tomography imaging and photothermal/ photodynamic/radiation synergistic cancer therapy显示文摘联合治疗是通常基于复杂 nanostructures 的利用,多重部件为 photothermal 作为相片热的精力变换器, photo-sensitizers,或剂量 intensifiers 工作的有希望的癌症治疗策略治疗(PTT ) ,光力学的治疗(太平洋夏季时间) ,或放射治疗(RT ) 。在这研究, ultrathin 钨氧化物 nanowires (W 18 O 49) 用一条 solvothermal 途径被综合并且作为多功能的 theranostic nanoplatform 检验了。在 vitro 并且在 vivo,分析证明这些 nanowires 能导致广泛的热 -- 并且汗衫在 980 nm 在附近下面的癌症房间的调停氧的损坏红外线(NIR ) 激光刺激。他们也被显示作为加强在放射治疗期间局部地并且有选择地提高放热精力免职的代理人的放射剂量工作。独自比作导致 NIR 的 PTT/PDT 和 RT, W 18 O 49-based synergistic tri 形式的治疗根除了异种皮移植肿瘤和没有复发被观察在以内一 9 月列在后面起来。而且,钨元素的强壮的 X 光检查变细能力(Z = 74, 4.438 厘米 2???? ?? ?? 佦 ? 畳 ?? 猯扵￣?? | Jianjian Qiu Qingfeng Xiao Xiangpeng Zheng Libo Zhang Huaiyong Xing Dalong Ni Yanyan Liu Shengjian Zhang Qingguo Ren Yanqing Hua Kuaile Zhao Wenbo Bu | 2015 | Nano Research2015，8，11： | 5 |
| 6 | CONSTANT WORK-POINT CONTROL FOR PARALLEL HYBRID SYSTEM WITH CAPACITOR ACCUMULATOR IN HYDRAULIC EXCAVATOR显示文摘在混合水力的开凿者的各种各样的蓄电池的限制被分析。基于经常的工作点控制把电容器用作蓄电池的一个程序被提出。模仿混合构造机械的试验性的系统的 A 被建立,并且经常的工作点上的试验性的学习控制因为有电容器蓄电池的平行混合系统被执行使用作为模仿的负担在实际工作从水力的开凿者的吊杆柱体导出的压力和流动率。两倍工作点控制的一个程序被进一步的实验建议并且证明。 | ZHANG Yanting WANG Qingfeng XIAO Qing FU Qiang | 2006 | Chinese Journal of Mechanical Engineering2006，19，4： | 4 |
| 7 | Effect of chronic corticosterone-induced depression on circadian rhythms and age-related phenotypes in mice显示文摘Disrupted circadian rhythms are a recognized effect of depression,and our previous article demonstrated an association between depression and premature aging,but the underlying mechanisms are not well understood.In the present study,we used a mouse model of chronic corticosterone (CORT)-treated depression to elucidate a mechanism by which depression may be associated with the circadian clock and mediate age-related phenotypes.Mice received a daily injection of 20 mg/kg CORT for 21 consecutive days,and the depression-like behaviors of mice were identified by the sucrose intake test,tail suspension test and open field test.Our findings indicated that CORT injection may be correlatedwith the circadian clock by impairing circadian rhythms or shifting the phase values of clock genes.We also showed that CORT-treated mice exhibited a significant gradual reduction in body weight gain with increased oxidative stress, including reduced activity of antioxidant-related enzymes,reduced glutathione:glutathione disulfide ratio and cytochrome (Cyt)-C level,and elevated reactive oxygen species content.Moreover, chronic CORT injection affected inflammatory responses,the production of mitochondrial ATP and telomere shortening,which may be associated with the Sirtuin 3 (SIRT3)signaling pathway. Additionally,chronic CORT injection disrupted the circadian rhythms of some indexes of aging phenotypes and altered the phase values of these indexes.Our findings suggest that psychologically stressful conditions such as depression are linked to changes in circadian rhythms and agerelated phenotypes. | Lingyan iVla Qichen Shen Song Yang Xiaoxian Xie Qingfeng Xiao Chuanan Yu Lisha Cao Zhengwei Fu | 2018 | Acta Biochimica et Biophysica Sinica2018，50，12： | 4 |
| 8 | Systems model-guided rice yield improvements based on genes controlling source, sink, and flow显示文摘A large number of genes related to source, sink,and flow have been identified after decades of research in plant genetics. Unfortunately, these genes have not been effectively utilized in modern crop breeding. This perspective paper aims to examine the reasons behind such a phenomenon and propose a strategy to resolve this situation. Specifically, we first systematically survey the currently cloned genes related to source, sink, and flow;then we discuss three factors hindering effective application of these identified genes, which include the lack of effective methods to identify limiting or critical steps in a signaling network, the misplacement of emphasis on properties, at the leaf, instead of the whole canopy level,and the non-linear complex interaction between source,sink, and flow. Finally, we propose the development of systems models of source, sink and flow, together with a detailed simulation of interactions between them and their surrounding environments, to guide effective use of the identified elements in modern rice breeding. These systems models will contribute directly to the definition of crop ideotype and also identification of critical features and parameters that limit the yield potential in current cultivars. | Pan Li Tiangen Chang Shuoqi Chang Xiang Ouyang Mingnan Qu Qingfeng Song Langtao Xiao Shitou Xia Qiyun Deng Xin-Guang Zhu | 2018 | Journal of Integrative Plant Biology2018，60，12： | 4 |
| 9 | Climatic significance of n-alkanes and their compound-specific dD values from lake surface sediments on the Southwestern Tibetan Plateau显示文摘The content and hydrogen isotope ratios of n-alkanes extracted from recent lake surface sediments sampled from nine lakes in three different climate zones on the Southwestern Tibetan Plateau were analyzed.Values were compared with n-alkanes in plants from lake drainages,and dD values of meteoric water,lake water,and mean annual precipitation.The results showed that n-C23was predominantly derived from aquatic plants,and n-C27–n-C33from terrestrial higher plants.The average carbon chain length of n-C27–n-C33(ACL27–33)was positively correlated with the mean annual precipitation.dD values of the long-chain n-alkanes n-C29and n-C31of terrestrial origin(varying between-214%and-169%,and-226%and-185%,respectively)were inversely correlated with mean annual precipitation;but in accordance with the average annual variations in dD(OIPC),dD values of n-C31were strongly related to the dD values of growing season meteoric water(R2=0.74).The large difference between dD values of n-C23of aquatic origin and n-C31(an average of about 27%)demonstrates the enrichment of the lake water dD compared to precipitation,caused by strong evaporation in the semiarid–arid areas of the southwestern Tibetan Plateau.Average value of en C25 31=p(-95%)is evidently higher than the value observed in European wet regions(-128%);besides,en C31(about-116%)is constant along the study transect(SD=9),which indicates that n-C31is a useful proxy for the environment. | Xing Hu Liping Zhu Yong Wang Junbo Wang Ping Peng Qingfeng Ma Jianfang Hu Xiao Lin | 2014 | Chinese Science Bulletin2014，59，24： | 3 |
| 10 | Growth of ultra-dense MoS_(2) nanosheets on carbon fibers to improve the mechanical and tribological properties of polyimide composites显示文摘To enhance the interface bonding of polyimide(PI)/carbon fiber(CF)composites,CFs were functionalized by introducing a polydopamine(PDA)transition layer,whose active groups provide absorption sites for the growth of molybdenum disulfide(MoS_(2))nanosheets and improve the bonding strength with PI.Uniform and dense MoS_(2) nanosheets with thicknesses of 30–40 nm on the surface of the PDA@CF were obtained via a subsequent hydrothermal method.As a result,the interface between the CF and the PI matrix becomes more compact with the help of the PDA transition layer and MoS_(2) nanosheets.This is beneficial in forming PI/CF–MoS_(2) composites with better thermal stability,higher tensile strength,and enhanced tribological properties.The lubricating and reinforcing effects of the hybrid CF–MoS_(2) in the PI composite are discussed in detail.The tensile strength of the PI/CF–MoS_(2) composite increases by 43%,and the friction coefficient and the wear rate reduce by 57%and 77%,respectively,compared to those of the pure PI.These values are higher than those of the PI/CF composites without MoS_(2) nanosheets.These results indicate that the CF–MoS_(2) hybrid material can be used as an additive to improve the mechanical and tribological properties of polymers. | Jin YANG Qingfeng XIAO Zhe LIN Yong LI Xiaohua JIA Haojie SONG | 2021 | Friction2021，9，5： | 3 |
| 11 | ePlant for quantitative and predictive plant science research in the big data era --Lay the foundation for the future model guided crop breeding, engineering and agronomy显示文摘背景在着急地在最近的十年统一陆地区域基础上的庄稼产量的全球人口,气候变化和停滞的增加打电话让一条新途径支持当代的庄稼改进。ePlant 与机械学的细节的高水平是植物生长和开发的一个数学模型遇见这挑战。结果 ePlant 集成为过程发生在开发的模块急速地不同时间( 108106 秒)并且空间( 101010 米)可伸缩,合并多样的物理、生物物理、生物化学的过程包括基因规定,新陈代谢的反应,底层运输和散开,精力吸收,转移和变换,机关形态发生,植物环境相互作用,等等。单个模块用一条 divide-and-conquer 途径被开发;在不同时间、空间的规模的模块进一步通过转移 variables.We 是综合的基于信息几何学建议一个监督学习过程为两知识发现和模型扩展或进展联合模型和数据。我们最后讨论一个全球协会的最近的形成,它在植物生物学包括专家,计算机科学,统计,农学, phenomics ,等等试图由支持模型作为一个社区努力被开发而不是在哪儿的一个新模型开发范例帮助 ePlant 或它的等价物的开发和应用程序主要由单个实验室努力开车。结论 ePlant 支持量、预兆的植物科学研究的一个主要研究工具,将在未来模型起一个关键作用指导庄稼工程,繁殖并且农学。 | Yi Xiao Tiangen Chang Qingfeng Song Shuyue Wang Danny Tholen Yu Wang Changpeng xin Guangyong Zheng Honglong Zhao Xin-Guang Zhu | 2017 | Frontiers of Electrical and Electronic Engineering in China2017，5，3： | 3 |
| 12 | Study of brain morphology change in Alzheimer’s disease and amnestic mild cognitive impairment compared with normal controls显示文摘Background With an aggravated social ageing level, the number of patients with Alzheimer's disease (AD) is gradually increasing, and mild cognitive impairment (MCI) is considered to be an early form of Alzheimer's disease. How to distinguish diseases in the early stage for the purposes of early diagnosis and treatment is an important topic. Aims The purpose of our study was to investigate the differences in brain cortical thickness and surface area among elderly patients with AD, elderly patients with amnestic MCI (aMCI) and normal controls (NC). Methods 20 AD patients, 21 aMCIs and 25 NC were recruited in the study. FreeSurfer software was used to calculate cortical thickness and surface area among groups. Results The patients with AD had less cortical thickness both in the left and right hemisphere in 17 of the 36 brain regions examined than the patients with aMCI or NC. The patients with AD also had smaller cerebral surface area both in the left and right hemisphere in 3 of the 36 brain regions examined than the patients with aMCI or NC. Compared with the NC, the patients with aMCI only had slight atrophy in the inferior parietal lobe of the left hemisphere, and no significant difference was found. Conclusion AD, as well as aMCI (to a lesser extent), is associated with reduced cortical thickness and surface area in a few brain regions associated with cognitive impairment. These results suggest that cortical thickness and surface area could be used for early detection of AD. | Huanqing Yang Hua Xu Qingfeng Li Yan Jin Weixiong Jiang Jinghua Wang Yina Wu Wei Li Cece Yang Xia Li Shifu Xiao Feng Shi Tao Wang | 2019 | General Psychiatry2019，32，2： | 3 |
| 13 | Control st-rategies of power system in hybrid hydraulic excavato-r 显示文摘 | Qing Xiao Qingfeng Wang Yanting Zhang | 2008 | Automation in Construcion2008，17，4： | 1 |
| 14 | Protoncon ductivity of phosphoric acid doped polybenzimidazole and its composites with inorganic proton conductors显示文摘 | He Ronghuan Li Qingfeng Xiao Gang | 2003 | J Membr Sci2003，226，： | 1 |
| 15 | Control strategies of power system in hybrid hydraulic excavator显示文摘 | XIAO Qing WANG Qingfeng ZHANG Yanting | 2008 | Automation in Construction2008，17，4： | 1 |
| 16 | Motion characteristic of a free piston linear engine显示文摘 | Xiao Jin Li Qingfeng Huang Zhen | 2010 | Applied Energy2010，87，4： | 1 |
| 17 | Control strate gies of power system in hybrid hydraulic excavator显示文摘 | Xiao Qing Wang Qingfeng Zhang Yanting | | 0，，04： | 1 |
| 18 | Re-operation for Hirschsprung’s disease: experience in 24 patients from China显示文摘 | Qingfeng Sheng Zhibao Lv Xianmin Xiao | 2012 | Pediatric Surgery International2012，，5： | 1 |
| 19 | Motion characteristic of a free piston linear engine显示文摘 | Jin Xiao Qingfeng Li Zhen Huang | 2009 | Applied Energy2009，，4： | 1 |
| 20 | Control Strategies of Power System in Hydraulic Excavator显示文摘 | XIAO Qing WANG Qingfeng ZHANG Yan-ting | 2008 | Automa- tion in Construction2008，17，4： | 1 |
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