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| 1 | Neuroprotective effects of Buyang Huanwu decoction on cerebral ischemia-induced neuronal damage显示文摘Among the various treatment methods for stroke, increasing attention has been paid to traditional Chinese medicines. Buyang Huanwu decoction is a commonly used traditional Chinese medicine for the treatment of stroke. This paper summarizes the active components of the Chinese herb, which is composed of Huangqi(Radix Astragali seu Hedysari), Danggui(Radix Angelica sinensis), Chishao(Radix Paeoniae Rubra), Chuanxiong(Rhizoma Ligustici Chuanxiong), Honghua(Flos Carthami), Taoren(Semen Persicae) and Dilong(Pheretima), and identifies the therapeutic targets and underlying mechanisms that contribute to the neuroprotective properties of Buyang Huanwu decoction. | Qingchun Mu Pengfei Liu Xitong Hu Haijun Gao Xu Zheng Haiyan Huang | 2014 | Neural Regeneration Research2014,9,17: | 32 |
| 2 | Bone marrow mesenchymal stem cell therapy in ischemic stroke: mechanisms of action and treatment optimization strategies显示文摘Animal and clinical studies have confirmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly understood. Here, we summarize the transplantation approaches, directional migration, differentiation, replacement, neural circuit reconstruction,angiogenesis, neurotrophic factor secretion, apoptosis, immunomodulation, multiple mechanisms of action,and optimization strategies for bone marrow mesenchymal stem cells in the treatment of ischemic stroke.We also explore the safety of bone marrow mesenchymal stem cell transplantation and conclude that bone marrow mesenchymal stem cell transplantation is an important direction for future treatment of cerebral ischemia. Determining the optimal timing and dose for the transplantation are important directions for future research. | Guihong Li Fengbo Yu Ting Lei Haijun Gao Peiwen Li Yuxue Sun Haiyan Huang Qingchun Mu | 2016 | Neural Regeneration Research2016,11,6: | 22 |
| 3 | Velocity-Free MS/AE Source Location Method for Three-Dimensional Hole-Containing Structures显示文摘Microseismic/acoustic emission(MS/AE)source localization method is crucial for predicting and controlling of potentially dangerous sources of complex structures.However,the locating errors induced by both the irregular structure and pre-measured velocity are poorly understood in existing methods.To meet the high-accuracy locating requirements in complex three-dimensional hole-containing structures,a velocity-free MS/AE source location method is developed in this paper.It avoids manual repetitive training by using equidistant grid points to search the path,which introduces A*search algorithm and uses grid points to accommodate complex structures with irregular holes.It also takes advantage of the velocity-free source location method.To verify the validity of the proposed method,lead-breaking tests were performed on a cubic concrete test specimen with a size of 10 cm10 cm10 cm.It was cut out into a cylindrical empty space with a size of/6cm10 cm.Based on the arrivals,the classical Geiger method and the proposed method are used to locate lead-breaking sources.Results show that the locating error of the proposed method is 1.20 cm,which is less than 2.02 cm of the Geiger method.Hence,the proposed method can effectively locate sources in the complex three-dimensional structure with holes and achieve higher precision requirements. | Longjun Dong Qingchun Hu Xiaojie Tong Youfang Liu | 2020 | Engineering2020,6,7: | 22 |
| 4 | Adenovirus-mediated CTLA4Ig gene inhibits infiltration of immune cells and cell apoptosis in rats after liver transplantation显示文摘AIM: To investigate the role of adenovirus-mediated CTLA4Ig gene therapy in inhibiting the infiltration of macrophages and CD8+T cells and cell apoptosis after liver transplantation. METHODS: The rat orthotopic liver transplantation model was applied. The rats were divided into three groups: group I: rejection control (SD-to-Wistar); group Ⅱ: acute rejection treated with intramuscular injection of CsA 3.0 mg/(kg·d) for 12 d (SD-to-Wistar+CsA); groupⅢ: injection of 1×10^9 PFU adenovirus-mediated CTLA41g gene liquor in dorsal vein of penis 7 d before liver transplantation (SD-to-Wistar+CTLA4Ig). Immunohistochemistry and transferase-mediated dUTP nick-end labeling (TUNEL )were used to analyze the expression of CTLA4Ig gene in liver, infiltration of macrophages and CD8+T cells, cell apoptosis in grafts at different time-points after liver transplantation. Histopathological examination was done. RESULTS: CTLA4Ig gene expression was positive in liver on d 7 after administering adenovirus-mediated CTLA4Ig gene via vein, and remained positive until day 60 after liver transplantation. Infiltration of macrophages and CD8+T cells in CTLA4Ig-treated group was less than in rejection control group and CsA-treated group. The apoptotic index of rejection group on d 3, 5, and 7 were significantly higher than that of CTLA4Ig-treated group. A good correlation was found between severity of rejection reaction and infiltration of immune activator cells or cell apoptotic index in grafts. CONCLUSION: CTEA4Ig gene is constantly expressed in liver and plays an important role in inducing immune tolerance, | Guo-Ping Jiang, Zhen-Hua Hu, Shu-Sen Zheng, Chang-Ku Jia, Ai-Bin Zhang, Wei-Lin Wang, Department of Hepatobiliary Pancreatic Surgery, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, The First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China | 2005 | World Journal of Gastroenterology2005,11,7: | 14 |
| 5 | The electromagnetic wave experiment for CSES mission: Search coil magnetometer显示文摘The seismic activities on the Earth can produce a disturbance of the electromagnetic field and particles in the ionosphere. The search coil magnetometer(SCM) mounted on China Seismo-Electromagnetic satellite(CSES) is designed to measure the magnetic field fluctuation of low frequency electromagnetic waves in the frequency range of 10 Hz–20 k Hz. The SCM comprises a three-axis search coil sensor mounted on a 4.5 m boom and an electronic box inside satellite module. The sampling rate of the SCM is 51.2 k Hz and the time resolution of the power spectrum density(PSD) is 2 s. The frequency resolution is 12.5 Hz.There are three operation modes: survey, detailed survey and calibration. In the survey mode, the SCM can provide a PSD in the whole frequency range of 10 Hz–20 k Hz and wave forms in the low frequency range below 2 k Hz while in the detailed survey mode the SCM can provide both PSD and wave forms in the whole frequency range of 10 Hz–20 k Hz. The sensitivity of the SCM instrument is 5.0×10^(-4) n T Hz^(-1/2) at 10 Hz, 5.0×10^(–5) n T Hz^(-1/2) at 200 Hz, 3.4×10^(-5) n T Hz^(-1/2) at 2 k Hz and 1.1×10^(-4) n T Hz^(-1/2) at 20 k Hz. The telemetry rate is ~0.85 Mbps in the survey mode and ~3.0 Mbps in the detailed survey mode. The phase difference between three axes can be made generally with a precision of less than 1.0°. The dynamic range of the SCM instrument is over 100 d B. The orthogonality of three mechanical axes of search coil senor is better than 0.13°. The performance of SCM can satisfy the requirement of scientific objectives of CSES mission. | CAO JinBin ZENG Li ZHAN Feng WANG ZuoGui WANG Yan CHEN Yu MENG QingChun JI ZhanQiang WANG PengFei LIU ZhongWei MA LingYu | 2018 | Science China(Technological Sciences)2018,61,5: | 13 |
| 6 | QTG-Seq Accelerates QTL Fine Mapping through QTL Partitioning and Whole-Genome Sequencing of Bulked Segregant Samples显示文摘Deciphering the genetic mechanisms underlying agronomic traits is of great importance for crop improvement. Most of these traits are controlled by multiple quantitative trait loci (QTLs), and identifying the underlying genes by conventional QTL fine-mapping is time-consuming and labor-intensive. Here, we devised a new method, named quantitative trait gene sequencing (QTG-seq), to accelerate QTL fine-mapping. QTGseq combines QTL partitioning to convert a quantitative trait into a near-qualitative trait, sequencing of bulked segregant pools from a large segregating population, and the use of a robust new algorithm for identifying candidate genes. Using QTG-seq, we fine-mapped a plant-height QTL in maize (Zea mays L.), qPH7, to a 300-kb genomic interval and verified that a gene encoding an NF-YC transcription factor was the functional gene. Functional analysis suggested that qPH7-encoding protein might influence plant height by interacting with a CO-like protein and an AP2 domain-containing protein. Selection footprint ana卜 ysis indicated that qPH7 was subject to strong selection during maize improvement. In summary, QTG-seq provides an efficient method for QTL fine-mapping in the era of “big data'. | Hongwei Zhang Xi Wang Qingchun Pan Pei Li Yunjun Liu Xiaoduo Lu Wanshun Zhong Minqi Li Linqian Han Juan Li Pingxi Wang Dongdong Li Yan Liu Qing Li Fang Yang Yuan-Ming Zhang Guoying Wang Lin Li | 2019 | Molecular Plant2019,12,3: | 13 |
| 7 | Design of structured-light vision system for tomato harvesting robot显示文摘In order to improve the operating precision of the harvesting robot,a vision system for intelligently identifying and locating the mature tomato was designed.The active detection method based on structured-light stereo vision was expected to deal with the problem of variable illumination and target occlusion in the glasshouse.The maximum between-cluster variances of hue(H)and saturation(S)value were adopted as the threshold for color segmentation,which weakened the impact on the image caused by the light intensity variation.Through the limit on the pixel size and circularity of the candidate areas,the vision system recognized the fruit area and removed the noise areas.The fruit’s 3D position was computed on the basis of spatial relationship between the laser plane and the camera,when the linear laser was projected on the centre area of the mature fruit.The blue view-scanning laser stripe pixels on the mature fruit were extracted according to its Cb color characteristic.As the field test results show,the measurement error on the fruit radius is less than 5 mm,the centre distance error between the fruit and camera is less than 7 mm,and the single axis coordinate error is less than 5.6 mm.This structured-light vision system could effectively identify and locate mature fruit. | Feng Qingchun Cheng Wei Zhou Jianjun Wang Xiu | 2014 | International Journal of Agricultural and Biological Engineering2014,7,2: | 12 |
| 8 | Design and test of tray-seedling sorting transplanter显示文摘In order to improve the automatic sorting and transplanting of tray-seedling and reduce labors strength,a new sorting transplanter was designed.According to the feature of normal seedling tray and manual grading method,the mechanical sorting procedure was defined.The key parts of sorting transplanter are as follows:an efficient transfer mechanism with aerodynamic buffer,a seedling identifying and measuring unit based on linear-structured vision,the extendible multi-grasper with wireless technology and the system controller.The experiments were conducted and showed that the transplanting success rate was 90.0% on the tray of 6×12 holes under the speed of 700 cycles per hour.The vision unit’s failed identifying rate for the superior pepper seedlings on five different trays was less than 10%,and the measurement error of seedling height was about 5 mm. | Feng Qingchun Zhao Chunjiang Jiang Kai Fan Pengfei Wang Xiu | 2015 | International Journal of Agricultural and Biological Engineering2015,8,2: | 12 |
| 9 | Where were the monsoon regions and arid zones in Asia prior to the Tibetan Plateau uplift?显示文摘The impact of the Tibetan Plateau uplit on the Asian monsoons and inland arid climates is an important but also controversial question in studies of paleoenvironmental change during the Cenozoic. In order to achieve a good understanding of the background for the formation of the Asian monsoons and arid environments, it is necessary to know the characteristics of the distribution of monsoon regions and arid zones in Asia before the plateau uplit. In this study, we discuss in detail the paterns of distribution of the Asian monsoon and arid regions before the plateau uplit on the basis of modeling results without topography from a global coupled atmosphere–ocean general circulation model, compare our results with previous simulation studies and available biogeological data, and review the uncertainties in the current knowledge. Based on what we know at the moment, tropical monsoon climates existed south of 20?N in South and Southeast Asia before the plateau uplit, while the East Asian monsoon was entirely absent in the extratropics. hese tropical monsoons mainly resulted from the seasonal shits of the Inter-Tropical Convergence Zone. here may have been a quasi-monsoon region in central-southern Siberia. Most of the arid regions in the Asian continent were limited to the latitudes of 20–40?N, corresponding to the range of the subtropical high pressure year-around. In the meantime, the present-day arid regions located in the relatively high latitudes in Central Asia were most likely absent before the plateau uplit. he main results from the above modeling analyses are qualitatively consistent with the available biogeological data. hese results highlight the importance of the uplit of the Tibetan Plateau in the Cenozoic evolution of the Asian climate patern of dry–wet conditions. Future studies should be focused on efects of the changes in land–sea distribution and atmospheric CO2 concentrations before and ater the plateau uplit, and also on cross-comparisons between numerical simulations and geological evidence, so that a comprehensive understanding of the evolution of the Cenozoic paleoenvironments in Asia can be achieved. | Xiaodong Liu Qingchun Guo Zhengtang Guo Zhi-Yong Yin Buwen Dong Robin Smith | 2015 | National Science Review2015,2,4: | 12 |
| 10 | Chain-type wireless sensor network node scheduling strategy显示文摘In order to reduce power consumption of sensor nodes and extend network survival time in the wireless sensor network(WSN), sensor nodes are scheduled in an active or dormant mode. A chain-type WSN is fundamentally different from other types of WSNs, in which the sensor nodes are deployed along elongated geographic areas and form a chain-type network topology structure. This paper investigates the node scheduling problem in the chain-type WSN. Firstly, a node dormant scheduling mode is analyzed theoretically from geographic coverage, and then three neighboring nodes scheduling criteria are proposed. Secondly, a hybrid coverage scheduling algorithm and dead areas are presented. Finally, node scheduling in mine tunnel WSN with uniform deployment(UD), non-uniform deployment(NUD) and optimal distribution point spacing(ODS) is simulated. The results show that the node scheduling with UD and NUD, especially NUD,can effectively extend the network survival time. Therefore, a strategy of adding a few mobile nodes which activate the network in dead areas is proposed, which can further extend the network survival time by balancing the energy consumption of nodes. | Guangzhu Chen Qingchun Meng Lei Zhang | 2014 | Journal of Systems Engineering and Electronics2014,25,2: | 9 |
| 11 | A new strawberry harvesting robot for elevated-trough culture显示文摘In order to improve robotic harvesting and reduce production cost,a harvesting robot system for strawberry on the elevated-trough culture was designed.It was supposed to serve for sightseeing agriculture and technological education.Based on the sonar-camera sensor,an autonomous navigation system of the harvesting robot was built to move along the trough lines independently.The mature fruits were recognized according to the H(Hue)and S(Saturation)color feature and the picking-point were located by the binocular-vision unit.A nondestructive end-effector,used to suck the fruit,hold and cut the fruit-stem,was designed to prevent pericarp damage and disease infection.A joint-type industrial manipulator with six degrees-of-freedom(DOF)was utilized to carry the end-effector.The key points and time steps for the collision-free and rapid motion of manipulator were planned.Experimental results showed that all the 100 mature strawberry targets were recognized automatically in the harvesting test.The success harvesting rate was 86%,and the success harvesting operation cost 31.3 seconds on average,including a single harvest operation of 10 seconds.The average error for fruit location was less than 4.6 mm. | Feng Qingchun Wang Xiu Zheng Wengang Qiu Quan Jiang Kai | 2012 | International Journal of Agricultural and Biological Engineering2012,5,2: | 8 |
| 12 | Design and test of robotic harvesting system for cherry tomato显示文摘Harvesting of fresh-eating cherry tomato was highly costly on labor and time.In order to achieve mechanical harvesting for the fresh-eating tomato,a new harvesting robot was designed,which consisted of a stereo visual unit,an end-effector,manipulator,a fruit collector,and a railed vehicle.The robot configuration and workflow design focused on the special cultivating condition.Three key parts were introduced in detail:a railroad vehicle capably moving on both ground and rail was adopted as the robot’s carrier,a visual servo unit was used to identify and locate the mature fruits bunch,and the end-effector to hold and separate the fruit bunch was designed based on the stalk’s mechanical features.The field test of the new developed robot was conducted and the results were analyzed.The successful harvest rate of the robot was 83%,however,each successful harvest averagely needed 1.4 times attempt,and a single successful harvesting cycle cost 8 s excluding the time cost on moving. | Qingchun Feng Wei Zou Pengfei Fan Chunfeng Zhang Xiu Wang | 2018 | International Journal of Agricultural and Biological Engineering2018,11,1: | 8 |
| 13 | May-June mean maximum temperature change during 1360-2005 as reconstructed by tree rings of Sabina Tibetica in Zaduo,Qinghai Province显示文摘Based on tree-ring samples collected from Zaduo area in southern Qinghai Province, a 646-year ring-width series was established. Using response function, correlation function and partial correlation analysis we found that the ring-width series is sensitive most to May and June mean maximum air temperature at Zaduo meteorological stations and the correlation is significantly negative. Therefore, May-June mean maximum air temperature in Zaduo area since 1360 is reconstructed using this ring-width series. The regression equation was cross-validated in the calibration period of 1961-2005. The calibration equation can explain 59.8% of the total variance. Since high temperature could reinforce evapotranspiration and result in water stress, the high values are more reliable than the low values in the reconstructed series. By further analyzing upon the reconstructed series, it shows that on the in-ter-annual scale there are 6 periods with higher temperature: 1438-1455, 1572-1612, 1684-1700, 1730-1754, 1812-1829 and 1853-1886; while there are 5 periods with lower temperature: 1547-1571, 1701-1729, 1755-1777, 1830-1852 and 1887-1910. There is no significant rising of temperature in recent 50 years. By comparison with the rings-width series nearby which are also sensitive to the mean maximum air temperature and the mean maximum temperature reconstruction by ring-widths, it is found that the variation of inter-annual scale is fairly common in the region. | SHI XingHe QIN NingSheng ZHU HaiFeng SHAO XueMei WANG QingChun ZHU XiDe | 2010 | Chinese Science Bulletin2010,55,26: | 8 |
| 14 | Some Investigations on Early Organization of Karst System显示文摘Some investigations on the early organization of karst system are carried out through modeling the dissolution evolution processes of stochastic fracture networks in carbonate rock. It is assumed that water flow in fracture network is laminar, and the dissolution rate process can be described with an empirical equation, The results suggest that a karst system is a self-organization system. It can spontaneously create higher hierarchical level out of a relative homogeneous structure through amplifying the microscopic heterogeneity of initial flow field. Under given boundary conditions, a karst system with initial fracture network of varied hierarchical levels is likely to have stronger tendency to lead to a typical karst system featuring conduit passages than a system with initial network of unique hierarchical level. Through merging local flow systems, a karst system concentrates the limited flow into a few pathways to promote the formation of higher hierarchical level. | Yu Qingchun(Geofront Laboratory, Department of Civil Engineering, Kyoto University, Kyoto 606-8501, Japan)Shen Jifang Wan Junwei(Department of Hydrogeology and Environmental Engineering, China University of Geosciences,Wuhan 430074, China)Ohnishi Yuzo(Geo | 1999 | Journal of Earth Science1999,18,4: | 8 |
| 15 | Tracing the settlement region of massive floating green algae in the Yellow Sea显示文摘Outbreaks of large-scale green tides formed by Ulva prolifera in the Yellow Sea (YS) cause heavy ecological damages and huge economic losses. However, the ecological consequences of green tides remain poorly understood due to the lack of knowledge on the settlement region of massive green algae floating in the YS. In this study, we established a method to trace the settlement region of floating green algae, using 28-isofucosterol preserved in sediment as the specific biomarker for green algae. Sterols including 28-isofucosterol in surface sediment samples collected during an investigation in the YS and the Bohai Sea (BS) in August 2015 were analyzed using gas chromatography coupled with a mass spectrometer (GC-MS). Based on the content of 28-isofucosterol in sediment samples, the potential settlement region of fl oating green algae was identifi ed in the sea area southeast to the Shandong Peninsula around the sampling site H06 (122.66°E, 36.00°N). This paper presents a first result on the settlement region of floating green algae in the YS for providing a solid basis to elucidate the ecological consequences of green tides in the area. | GENG Huixia YU Rencheng ZHANG Qingchun YAN Tian KONG Fanzhou ZHOU Mingjiang | 2019 | Journal of Oceanology and Limnology2019,37,5: | 7 |
| 16 | Natural products as LSD1 inhibitors for cancer therapy显示文摘Natural products generally fall into the biologically relevant chemical space and always possess novel biological activities, thus making them a rich source of lead compounds for new drug discovery. With the recent technological advances, natural product-based drug discovery is now reaching a new era. Natural products have also shown promise in epigenetic drug discovery, some of them have advanced into clinical trials or are presently being used in clinic. The histone lysine specific demethylase1(LSD1), an important class of histone demethylases, has fundamental roles in the development of various pathological conditions. Targeting LSD1 has been recognized as a promising therapeutic option for cancer treatment. Notably, some natural products with different chemotypes including protoberberine alkaloids, flavones, polyphenols, and cyclic peptides have shown effectiveness against LSD1. These natural products provide novel scaffolds for developing new LSD1 inhibitors. In this review, we mainly discuss the identification of natural LSD1 inhibitors, analysis of the co-crystal structures of LSD1/natural product complex, antitumor activity and their modes of action. We also briefly discuss the challenges faced in this field. We believe this review will provide a landscape of natural LSD1 inhibitors. | Yuan Fang Chao Yang Zhiqiang Yu Xiaochuan Li Qingchun Mu Guochao Liao Bin Yu | 2021 | Acta Pharmaceutica Sinica B2021,11,3: | 6 |
| 17 | Genomic, Transcriptomic, and Phenomic Variation Reveals the Complex Adaptation of Modern Maize Breeding显示文摘 | Haijun Liu Xiaqing Wang Marilyn L. Warburton Weiwei Wen Minliang Jin Min Deng Jie Liu Hao Tong Qingchun Pan Xiaohong Yang Jianbing Yan | 2015 | Molecular Plant2015,8,6: | 6 |
| 18 | Fuzzy sliding mode control guidance law with terminal impact angle and acceleration constraints显示文摘In this paper, a novel fuzzy sliding mode control(FSMC) guidance law with terminal constraints of miss distance, impact angle and acceleration is presented for a constant speed missile against the stationary or slowly moving target. The proposed guidance law combines the sliding mode control algorithm with a fuzzy logic control scheme for the lag-free system and the first-order lag system. Through using Lyapunov stability theory, we prove the sliding surface converges to zero in finite time. Furthermore, considering the uncertain information and system disturbances, the guidance gains are on-line optimized by fuzzy logic technique. Numerical simulations are performed to demonstrate the performance of the FSMC guidance law and the results illustrate the validity and effectiveness of the proposed guidance law. | Qingchun Li Wensheng Zhang Gang Han Yuan Xie | 2016 | Journal of Systems Engineering and Electronics2016,27,3: | 6 |
| 19 | A Principle of Astronomical Three-dimensional Position Fixing Based on Single Baseline Radio Interferometry显示文摘 | WANG Anguo LI Hui WANG Yan ZHANG Lei CAO Qingchun | 2011 | Chinese Journal of Electronics2011,20,1: | 5 |
| 20 | Continental drift, plateau uplift, and the evolutions of monsoon and arid regions in Asia, Africa, and Australia during the Cenozoic显示文摘Monsoon and arid regions in the Asia-Africa-Australia(A-A-A) realm occupy more than 60% of the total area of these continents. Geological evidence showed that significant changes occurred to the A-A-A environments of the monsoon and arid regions, the land-ocean configuration in the Eastern Hemisphere, and the topography of the Tibetan Plateau(TP) in the Cenozoic. Motivated by this background, numerical experiments for 5 typical geological periods during the Cenozoic were conducted using a coupled ocean-atmosphere general circulation model to systemically explore the formations and evolutionary histories of the Cenozoic A-A-A monsoon and arid regions under the influences of continental drift and plateau uplift. Results of the numerical experiments indicate that the timings and causes of the formations of monsoon and arid regions in the A-A-A realm were very different. The northern and southern African monsoons existed during the mid-Paleocene, while the South Asian monsoon appeared in the Eocene after the Indian Subcontinent moved into the tropical Northern Hemisphere. In contrast, the East Asian monsoon and northern Australian monsoon were established much later in the Miocene. The establishment of the tropical monsoons in northern and southern Africa, South Asia, and Australia were determined by both the continental drift and seasonal migration of the Inter-Tropical Convergence Zone(ITCZ), while the position and height of the TP were the key factor for the establishment of the East Asian monsoon. The presence of the subtropical arid regions in northern and southern Africa,Asia, and Australia depended on the positions of the continents and the control of the planetary scale subtropical high pressure zones, while the arid regions in the Arabian Peninsula and West Asia were closely related to the retreat of the Paratethys Sea. The formation of the mid-latitude arid region in the Asian interior, on the other hand, was the consequence of the uplift of the TP.These results from this study provide insight to the important roles played by the earth's tectonic boundary conditions in the formations and evolutions of regional climates during geological times. | Xiaodong LIU Buwen DONG Zhi-Yong YIN Robin S.SMITH Qingchun GUO | 2019 | Science China Earth Sciences2019,62,7: | 5 |