6篇
您的检索式：作者名="Qu Minghai"
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| 1 | A novel method for preparing poly ( ethylene terephthalate)/BaS04 nanocomposites显示文摘 | QU Minghai WANG Yuzhong WANG Chuan | 2005 | J Eur Polym2005，41，11： | 1 |
| 2 | Investigation of interfacial modification for flame retardant ethylene vinyl acetate copolymer/alumina trihydrate nanocomposites 显示文摘 | Zhang Xingui Gao Fen Qu Minghai | 2005 | Polymer Degradation and Stability2005，，87： | 1 |
| 3 | Preparation and Flammability of a Novel Intumescent Flame-retardant Poly ( ethylene-co-vinyl Acetate ) System显示文摘 | WANG DEYI CAI XIAOXIA QU MINGHAI | 2008 | Polymer Degradation and Stability2008，93，12： | 1 |
| 4 | Preparation and flammability of a novel intumescent flame-retardant poly ( ethylene-co-vinyl acetate) system 显示文摘 | Wang Deyi Cai Xiaoxia Qu Minghai | 2008 | Polymer Degrada- tion and Stability2008，93，12： | 1 |
| 5 | Preparation and flammability of a novel intumescent flame-retardant poly ( ethylene-co-vinyl acetate) system 显示文摘 | Wang Deyi Cai Xiaoxia Qu Minghai | 2008 | Polymer Degradation and Stability2008，93，： | 1 |
| 6 | Melphalan-loaded methoxy poly(ethylene glycol)-poly(D,L-lactide)copolymer nanomicelles in the treatment of multiple myeloma显示文摘Multiple myeloma(MM)is the second most common hematological tumor characterized by the proliferation of monoclonal plasma cells.Melphalan(MEL)is commonly used in the treatment of MM and is especially essential for patients undergoing autologous stem cell transplantation(ASCT).Although many drugs for MM have been developed in recent years,chemotherapy followed by ASCT remains the optimal option.Melphalan,the backbone of the conditioning regimen,brings severe toxicities at a high dose.Nanodrug delivery systems enable drugs to be highly effective and have low toxicity.In this study,methoxy poly(ethylene glycol)-poly(D,L-lactide)copolymer(MPEG-PDLLA)was chosen to encapsulate melphalan,and the characteristics,effectiveness,and safety of MEL/MPEG-PDLLA in vitro and in vivo were investigated.MEL/MPEG-PDLLA showed slow release and was easily engulfed by MM cells despite a result of the antitumor assay comparable to that of free melphalan in vitro.The in vivo results showed that MEL/MPEG-PDLLA could significantly alleviate tumor burden and prolong survival time without increasing the toxicity to vital organs.In addition,MEL/MPEG-PDLLA could significantly reduce the damage to the intestinal mucosa caused by melphalan.In conclusion,MEL/MPEG-PDLLA shows improved antitumor activity and has the potential to alleviate pains of MM patients undergoing ASCT. | Yingying Chen Qiang Zeng Bingyang Chu Zhigang Liu Xue Wei Mengran Chen Peipei Yang Minghai Tang Ting Niu Yongqian Jia Ying Qu Zhiyong Qian | 2023 | Chinese Chemical Letters2023，34，9： | 0 |
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