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    题名 作者 年代 出处 被引量
1Influence of Aggregate Type and Size on Ductility and Mechanical Properties of Engineered Cementitious Composites显示文摘Sahmaran Mustafa Lachemi Mohamed Hossain Khandaker M A Ranade Ravi Li Victor C 2009ACI Materials Journal2009,,3:2
2Emerging role of caldesmon in cancer:A potential biomarker for colorectal cancer and other cancers显示文摘Colorectal cancer(CRC) is a devastating disease, mainly because of metastasis. As a result, there is a need to better understand the molecular basis of invasion and metastasis and to identify new biomarkers and therapeutic targets to aid in managing these tumors. The actin cytoskeleton and actin-binding proteins are known to play an important role in the process of cancer metastasis because they control and execute essential steps in cell motility and contractility as well as cell division. Caldesmon(CaD) is an actin-binding protein encoded by the CALD1 gene as multiple transcripts that mainly encode two protein isoforms: High-molecular-weight CaD, expressed in smooth muscle, and low-molecular weight CaD(l-CaD), expressed in nonsmooth muscle cells. According to our comprehensive review of the literature, CaD, particularly l-CaD, plays a key role in the development, metastasis, and resistance to chemoradiotherapy in colorectal, breast, and urinary bladder cancers and gliomas, among other malignancies. CaD is involved in many aspects of the carcinogenic hallmarks, including epithelial mesenchymal transition via transforming growth factor-beta signaling, angiogenesis, resistance to hormonal therapy, and immune evasion. Recent data show that CaD is expressed in tumor cells as well as in stromal cells, such as cancerassociated fibroblasts, where it modulates the tumor microenvironment to favor the tumor. Interestingly, CaD undergoes selective tumor-specific splicing, and the resulting isoforms are generally not expressed in normal tissues, making these transcripts ideal targets for drug design. In this review, we will analyze these features of CaD with a focus on CRC and show how the currently available data qualify CaD as a potential candidate for targeted therapy in addition to its role in the diagnosis and prognosis of cancer.Alya R Alnuaimi Vidhya A Nair Lara J Bou Malhab Eman Abu-Gharbieh Anu Vinod Ranade Gianfranco Pintus Mohamad Hamad Hauke Busch Jutta Kirfel Rifat Hamoudi Wael M Abdel-Rahman 2022World Journal of Gastrointestinal Oncology2022,14,9:2
3Hydrodynamics of trickle bed reactors:experiments and CFD modeling显示文摘Gunjal P R Kashid M N Ranade V V Chaudhuri R V 0,,16:1
4Ex-pression of survivin and p53 proteins and their correlationwith hormone receptor status in Indian breast cancer pa-tients显示文摘Ranade K J Nerurkar A V Phulpagar M D 2009Indian J Med Sci2009,63,11:1
5Reversal of phototaxis in the larvae of Polydora pulchra Carazzi (Polychaeta,Spionidae)显示文摘RANADE M R 1957Nature1957,179,:1
6Evaluating EMMS model for simulating high solid flux risers显示文摘Naren P R Lali A M Ranade V V 0,,8:1
7Industrial heat pumps: where and when? 显示文摘Ranade S M Chao Y T 1990Hydrocarbon Process1990,94,10:1
8Hydrodynamic of bubble column re- actors at high gas velocity: Experiments and computational fluid dynamics (CFD) simulations显示文摘Ranade V V Rampure M 2007Industrial & Engineering Chem- istry Research2007,46,25:1
9The reaction between a gas and a solid in a nonisothermal packed bed: Simulation and experiments显示文摘Ranade M G Evans J W 1980Industrial and Engineering Chemistry Process Design and Development1980,19,1:1
10Adhesion and removal of fine particles on surfaces显示文摘Ranade M B 1987Aerosol Science and Technology1987,7,2:1
11Expression of survivin and p53 proteins and their correlation with hormone receptor status in Indian breast cancer patients显示文摘Ranade K J Nerurkar A V Phulpagar M D 2009Indian J Med Sci2009,63,11:1
12Hy- drodynamics of bubble column reactors at high gas velocity: experiments and computational fluid dynamics (CFD) sim- ulations 显示文摘RAMPURE M R KULKARNI A A RANADE V V 2007Industrial & Engineering Chemistry Research2007,46,25:1
13Atmospheric plasma deposited dense silica coatings on plastics 显示文摘CUI L Y RANADE A N MATOS M A 2012ACS Applied Materials & Interfaces2012,4,12:1
14Industrial heat pumps :where and when 显示文摘Ranade S M Chao Y T 1990Hydrocarbon Process1990,94,10:1
15Study of Nd3+,Pd2+,Pt4+,and Fe3+ dopant effect on photoreactivity of TiO2 nanoparticles显示文摘Ranade M Navrotsky A Zhang H 2002Proc Natl Acad Sci USA2002,99,2:1
16Hydrodynamics of bubble column reactors at high gas velocity:experiments and computational fluid dynamics(CFD)simulations显示文摘Rampure M R Kulkarni A A Ranade V V 0,,25:1
17High-throughput genotyping with single nucleotide polymorphisms 显示文摘RANADE K CHANG M S TING C T 2001Genome Res2001,11,7:1
18Radiation dose distributions in three dimen- sions from tomographic optical density scanning of polymer gels, I : Development of an optical scanner显示文摘GORE J C RANADE M MARYANSKI M J 1996Physics in Medicine and Biology1996,41,12:1
19Influence of vehicle front end design on pedestrian lower leg performance for SUV class vehicle显示文摘Bhagat M Chalipat S Ranade A 2011SAE International Journal of Passenger Cars- Mechanical Systems2011,4,1:1
20Computational snapshot of flow generated by axial impellers in baffled stirred vessels 显示文摘RANADE V V DOMMETI S M S 1996Trans IChemE1996,74,4:1
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