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| 1 | A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV) infected pneumonia(standard version)显示文摘In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province;and then named '2019 novel coronavirus(2019-nCoV)' by the World Health Organization(WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world’s attention but without treatment and control manual. For the request from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline according to the rapid advice guidelines methodology and general rules of WHO guideline development;we also added the first-hand management data of Zhongnan Hospital of Wuhan University. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control(including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue for 2019-nCoV infections. This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV. | Ying-Hui Jin Lin Cai Zhen-Shun Cheng Hong Cheng Tong Deng Yi-Pin Fan Cheng Fang Di Huang Lu-Qi Huang Qiao Huang Yong Han Bo Hu Fen Hu Bing-Hui Li Yi-Rong Li Ke Liang Li-Kai Lin Li-Sha Luo Jing Ma Lin-Lu Ma Zhi-Yong Peng Yun-Bao Pan Zhen-Yu Pan Xue-Qun Ren Hui-Min Sun Ying Wang Yun-Yun Wang Hong Weng Chao-Jie Wei Dong-Fang Wu Jian Xia Yong Xiong Hai-Bo Xu Xiao-Mei Yao Yu-Feng Yuan Tai-Sheng Ye Xiao-Chun Zhang Ying-Wen Zhang Yin-Gao Zhang Hua-Min Zhang Yan Zhao Ming-Juan Zhao Hao Zi Xian-Tao Zeng Yong-Yan Wang Xing-Huan Wang 无 | 2020 | Military Medical Research2020，7，1： | 161 |
| 2 | Coral reef-like polyanaline nanotubes prepared by a reactive template of manganese oxide for supercapacitor electrode显示文摘由 nanopaticles 组成的珊瑚像礁石的 PANI nanotubes 被锰氧化物的一个反应模板成功地综合。结构被使用 SEM, TEM,和英尺红外描绘,并且这些 nanotubes 的 supercapacitive 行为与周期的 voltammetry (CV ) 被调查,并且 chargedischarge 分别地测试。533 F/g 的一个最大的特定的电容能在 1 mol/L 被完成有 0.2 ~ 0.8 V 的潜在的范围的水的 H2SO4 (对浸透的甘汞电极) 在为 PANI 电极的一种一半房间安装配置,为电气化学的电容器在电极材料建议它的潜在的申请。 | Ling Ren Wang Fen Ran Yong Tao Tan Lei Zhao Ling Bin Kong Long Kang | 2011 | Chinese Chemical Letters2011，22，8： | 8 |
| 3 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 4 | Characterizing the induction of diabetes in juvenile cynomolgus monkeys with different doses of streptozotocin显示文摘Juvenile(2-3 years old) cynomolgus monkeys are frequently used as recipients in non-human primate islet transplantation studies.The aim of this study was to examine the effects of different doses of streptozotocin(STZ),and find the optimal dose for inducing diabetes in these monkeys.Fifteen juvenile(2-3 years old) cynomolgus monkeys were separated into three groups and administered with different doses of STZ(100,68 or 60 mg kg-1).Basal and glucose-stimulated blood glucose,insulin,and C-peptide levels,as well as body weights were monitored.Hepatic and renal function tests and pancreatic immunohistochemistry were performed before and after STZ treatment.Monkeys treated with both 100 and 68 mg kg-1 of STZ exhibited continuous hyperglycemia,which coincided with a nearly complete loss of islet--cells.Two monkeys received 60 mg kg-1 of STZ,but only one became completely diabetic.During the first week following STZ treatment,hepatic and renal function slightly increased in these three groups.However,24 hours post-STZ,serum total bile acid levels were significantly increased in monkeys treated with 100 mg kg-1 than those treated with 68 mg kg-1 of STZ(P<0.05).These data suggest that 100 mg kg-1 and 68 mg kg-1 of STZ can safely induce diabetes in cynomolgus monkeys aged 2-3 years,but 68 mg kg-1 of STZ,rather than 100 mg kg-1 of STZ,may be more appropriate for inducing diabetes in these monkeys.Furthermore,body surface area,rather than body weight,was a more reliable determinant of dosage,where 700 mg m-2 of STZ should be the lower limit for inducing diabetes in juvenile monkeys. | ZOU ChunLin WANG JiaYin WANG ShuYan HUANG Fen REN ZhenHua CHEN ZhiGuo ZHANG YU | 2012 | Science China(Life Sciences)2012，55，3： | 3 |
| 5 | Immunogenicity of HGV NS5 protein expressed from Sf9 insect cells显示文摘INTRODUCTIONAlthough reliable assays for the detection ofhepatitis C virus and E virus became available, still10% 20% hepatitis are not caused byhepatitis A-E virus[1-3]. In 1996, two research groups isolatedthis agent independently and almost simultaneouslyand named hepatitis G virus and GB virus C,respectively[4-7]. | Hao Ren Fen Lu Zhu Shi Ying Zhu Yan Bin Song Zhong Tian Qi Department of Microbiology, Second Military Medical University, Shanghai 200433, China | 2001 | World Journal of Gastroenterology2001，7，1： | 3 |
| 6 | Ginger-indirect moxibustion plus acupuncture versus acupuncture alone for chronic fatigue syndrome:a randomized controlled trial显示文摘OBJECTIVE:To assess the efficacy and safety of gingerindirect moxibustion for chronic fatigue syndrome(CFS).METHODS:In this central randomized,controlled trial,290 CFS participants were recruited and randomly allocated to group A(ginger-indirect moxibustion plus acupuncture)or group B(acupuncture alone).The study consisted of a treatment period of 8 weeks with a total of 24 treatments(3 sessions per week,every other day),and a follow-up period of 12 weeks.The outcome was measured by Fatigue Severity Scale(FSS),Psychological Health Report(SPHERE),the Self-rating depression scale(SDS)and the Hamilton anxiety scale(HAMA)at baseline,2,4,6,8,12 and 20 weeks.RESULTS:With the treatment undergoing,the changes of FSS,SPHERE,SDS and HAMA scores in both groups increased gradually,and the effect maintained at the 12th week.Between groups,significantly higher score changes were seen in group A in FSS after 4 weeks treatment(11.94 vs 9.12,95%CI:0.94,4.7)and in SPHERE after 2 weeks treatment(3.7 vs 2.27,95%CI:0.56,2.31).But for SDS and HAMA,the improvement did not differ significantly between groups.No severe adverse events were reported.CONCLUSION:Ginger-indirect moxibustion is a safe and effective intervention to relieve fatigue and accompanying physical symptoms of CFS. | MA Tingting WU Jie YANG Lijie FENG Fen YANG Huilin ZHANG Jinhua ZHONG Yanjin NING Qing HUANG Lirong LIN Youbing YAN Jue CHEN Guiquan HOU Tianshu WANG Li REN Yuanfang TAN Jing | 2022 | Journal of Traditional Chinese Medicine2022，42，2： | 2 |
| 7 | Embedding physics domain knowledge into a Bayesian network enables layer-by-layer process innovation for photovoltaics显示文摘Process optimization of photovoltaic devices is a time-intensive,trial-and-error endeavor,which lacks full transparency of the underlying physics and relies on user-imposed constraints that may or may not lead to a global optimum.Herein,we demonstrate that embedding physics domain knowledge into a Bayesian network enables an optimization approach for gallium arsenide(GaAs)solar cells that identifies the root cause(s)of underperformance with layer-by-layer resolution and reveals alternative optimal process windows beyond traditional black-box optimization.Our Bayesian network approach links a key GaAs process variable(growth temperature)to material descriptors(bulk and interface properties,e.g.,bulk lifetime,doping,and surface recombination)and device performance parameters(e.g.,cell efficiency).For this purpose,we combine a Bayesian inference framework with a neural network surrogate device-physics model that is 100×faster than numerical solvers.With the trained surrogate model and only a small number of experimental samples,our approach reduces significantly the time-consuming intervention and characterization required by the experimentalist.As a demonstration of our method,in only five metal organic chemical vapor depositions,we identify a superior growth temperature profile for the window,bulk,and back surface field layer of a GaAs solar cell,without any secondary measurements,and demonstrate a 6.5%relative AM1.5G efficiency improvement above traditional grid search methods. | Zekun Ren Felipe Oviedo Maung Thway Siyu I.P.Tian Yue Wang Hansong Xue Jose Dario Perea Mariya Layurova Thomas Heumueller Erik Birgersson Armin G.Aberle Christoph J.Brabec Rolf Stangl Qianxiao Li Shijing Sun Fen Lin Ian Marius Peters Tonio Buonassisi | 2020 | npj Computational Materials2020，，1： | 2 |
| 8 | Theoretical analysis for mechanical erosion of carbon-base materials in ablation 显示文摘 | Ren Fen Sun H S Liu L Y | 1996 | Journal of Thermophysics and Heat Transfer1996，10，4： | 1 |
| 9 | Factors that influence acceptance of web - based e - learning systems for the in - service education of junior high school teachers in Taiwan 显示文摘 | Hong - Ren Chen a Hsiao - Fen Tseng | 2012 | Evaluation and Program Planning2012，35，： | 1 |
| 10 | Arabinose substitution degree in xylan positively affects lignocellulose enzymatic digestibility after various NaOH/H 2 SO 4 pretreatments in Miscanthus显示文摘 | Fengcheng Li Shuangfeng Ren Wei Zhang Zhengdan Xu Guosheng Xie Yan Chen Yuanyuan Tu Qing Li Shiguang Zhou Yu Li Fen Tu Lin Liu Yanting Wang Jianxiong Jiang Jingping Qin Shizhong Li Qiwei Li Hai-Chun Jing Fasong Zhou Neal Gutterson Liangcai Peng | 2012 | Bioresource Technology2012，，： | 1 |
| 11 | Couple's infertility in relation to male smoking in a Chinese rural area显示文摘吸烟是繁殖健康的一个著名风险因素。然而,在富饶上的父亲的吸烟的效果是广泛地检验的更少。我们在西南中国的一个多山的区域进行了代表性的研究估计在夫妇富饶上的男性吸烟的效果。在学习区域的 18-49 年的 8200 对夫妇的一个总数被邀请参予学习。在里面人会见被执行包括吸并且喝习惯收集夫妇,和丈夫生活方式因素的人口统计的特征。信息准时回顾地被收集到怀孕(TTP ) 。不孕被定义为失败在常规没有防卫的交际以后完成临床的怀孕 12 个月。逻辑回归模型被用来估计在男性吸烟和不孕之间的协会。7025 对夫妇的一个总数总之被包括。在为潜在的 confounders 调整以后,如果丈夫吸烟了,夫妇是更可能的受不了不孕(调整机会比率[aOR ]=1.28, 95% CI:1.08-1.52 ) 在第一怀孕前。在分析根据吸持续时间的丈夫的意见被执行以后,增加的风险在 5-10 年的相对更长的吸烟持续时间开始了(aOR = 1.58, 95% CI:1.26-1.99 ) 并且一个更强壮的协会(aOR = 3.34, 95% CI:2.45-4.56 ) 在 10 年的组被观察。类似的模式被作出对有利的裁决每天和香烟的全部的数量吸的香烟的数字吸烟了。从我们的调查结果,我们断定男性吸烟可以在夫妇不孕上有不利影响。 | Fen Yang Lin Li Jian-Ping Chen Xiao-Qin Liu Chun-Li Zhong Yuan Yang Yan-Feng Ren Wei Yuan Hong Liang Mao-Hua Miao | 2017 | Asian Journal of Andrology2017，19，3： | 1 |
| 12 | Effects of azide on electron transport of exoelectrogens in air-cathode microbial fuel cells 显示文摘 | ZHOU X QU Y KIM B H ChOO P Y LIU J DU Y HE W CHANG I S REN N FEN N | 2014 | B ioresour Technol2014，169，： | 1 |
| 13 | Ward novel strategies for the treatment of sepsis 显示文摘 | Niels C、 Reidmann Ren - Fen Guo Peter A | 2003 | Nutrue medicine2003，5，： | 1 |
| 14 | Effects of additives and templates on calcium carbonate mineralization in vitro 显示文摘 | REN D FEN G Q L BOURRAT X | 2011 | Micron2011，42，3： | 1 |
| 15 | A generalized dy- namic herding model with feed-back interactions显示文摘 | ZHENG Bo REN Fen TRIMPER S | 2004 | Physica A2004，343，： | 1 |
| 16 | Bioleaching of a low grade nickel-copper-cobalt sulfide ore显示文摘 | YANG Cong-ren QIN Wen-qing LAI Shao-shi WANG Jun ZHANG Yan-sheng HAO Fen REN Liu-yi ZHUANG Tian CHANG Zi-yong | 2011 | Hydrometallurgy2011，106，12： | 1 |
| 17 | Research on the Contents of Chinese Seabucklthorn Fruit Oil and Its Application to Chloasma Treatments显示文摘 | Hanqing Xu Junfeng Ren Huili Xu Kefeng Sun Ailin Lv Jie Fen | 2005 | Journal of US-China Medical Science2005，2，6： | 1 |
| 18 | Survey of Depression by Beck Depression Inventory in Uremic Patients Undergoing Hemodialysis and Hemodiafiltration显示文摘 | Shu‐Fen Su Hwee‐Yeong Ng Tiao‐Lai Huang Po‐Jui Chi Yueh‐Ting Lee Chun‐Ren Lai Yau‐Hsing Lin Pei‐Chen Huang Chien‐Te Lee | 2012 | Therapeutic Apheresis and Dialysis2012，，6： | 1 |
| 19 | The Reaserch of Displacement Oil of the Polymer System with the Low Interfacial Tension Conditions显示文摘 | Ma Wen Guo Guo Quan Li Dan Liu Ren Qiang Xia Hui Fen | 2012 | 2012 (535)2012，，535： | 1 |
| 20 | Visible light photocatalytic performance of hierarchical BiOBr microspheres synthesized via a reactable ionic liquid显示文摘 | Bo Chai Huan Zhou Fen Zhang Xiang Liao Meixia Ren | 2014 | Materials Science in Semiconductor Processing2014，，： | 1 |
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