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| 1 | Immunoexpression of cyclooxygenase-2 in primary gastric carcinomas and lymph node metastases显示文摘AIM: To evaluate immunoexpression of cyclooxygenase-2 (COX-2) in primary gastric carcinomas and respective lymph node metastases. METHODS: Immunohistochemistry to analyze COX-2 expression was performed on tissue microarray slices obtained from 36 specimens of gastrectomy and satellite lymph nodes from patients with gastric carcinoma. RESULTS: Immunostaining was seen in most cases, and COX-2 expression was higher in lymph node me-tastases than in corresponding primary gastric tumors of intestinal, diffuse and mixed carcinomas, with a statistically signif icant difference in the diffuse histotype (P = 0.0108). CONCLUSION: COX-2 immunoexpression occurs frequently in primary gastric carcinomas, but higher expression of this enzyme is observed in lymph node metastases of the diffuse histotype. | Paulo RC Almeida Francisco VA Ferreira Cássio C Santos Francisco D Rocha-Filho Raul RP Feitosa Esther AA Falco Belise K Cavada Roberto CP Lima-Júnior Ronaldo A Ribeiro | 2012 | World Journal of Gastroenterology2012，18，8： | 14 |
| 2 | Neo-adjuvant chemo(radio)therapy in gastric cancer: Current status and future perspectives显示文摘In the last 20 years, several clinical trials on neoadjuvant chemotherapy and chemo-radiotherapy as a therapeutic approach for locally advanced gastric cancer have been performed. Even if more data are necessary to define the roles of these approaches, the results of preoperative treatments in the combined treatment of gastric adenocarcinoma are encouraging because this approach has led to a higher rate of curative surgical resection. Owing to the results of most recent randomized phase III studies, neoadjuvant chemotherapy for locally advanced resectable gastric cancer has satisfied the determination of level I evidence. Remaining concerns pertain to the choice of the optimal therapy regimen, strict patient selection by accurate pre-operative staging, standardization of surgical procedures, and valid criteria for response evaluation. New well-designed trials will be necessary to find the best therapeutic approach in pre-operative settings and the best way to combine old-generation chemotherapeutic drugs with new-generation molecules. | Alberto Biondi Maria C Lirosi Domenico D'Ugo Valeria Fico Riccardo Ricci Francesco Santullo Antonia Rizzuto Ferdinando CM Cananzi Roberto Persiani | 2015 | World Journal of Gastrointestinal Oncology2015，7，12： | 13 |
| 3 | Listeria monocytogenes following orthotopic liver transplantation:Central nervous system involvement and review of the literature显示文摘Listeria monocytogene is a well-recognized cause of bacteremia in immunocompromised individuals,including solid organ transplant recipients,but has been rarely reported following orthotopic liver transplantation. We describe a case of listeria meningitis that occurred within a week after liver transplantation. The patient developed a severe headache that mimicked tacrolimus encephalopathy,and was subsequently diagnosed with listeria meningitis by cerebrospinal fluid culture. The infection was successfully treated with three-week course of intravenous ampicillin. Recurrent hepatitis C followed and was successfully treated with interferon alfa and ribavirin. Fourteen cases of listeriosis after orthotopic liver transplantation have been reported in the English literature. Most reported cases were successfully treated with intravenous ampicillin. There were four cases of listeria meningitis,and the mortality of them was 50%. Early detection and treatment of listeria meningitis are the key to obtaining a better prognosis. | Shugo Mizuno Ivan R Zendejas Alan I Reed Robin D Kim Richard J Howard Alan W Hemming Denise C Schain Consuelo Soldevila-Pico Roberto J Firpi Shiro Fujita | 2007 | World Journal of Gastroenterology2007，13，32： | 2 |
| 4 | Sequential assembly and polymerization of the polyprenol-linked pentasacchariderepeating unit of the Xanthan polysaccharide in Xanthomonas campestris显示文摘 | Luis I Roberto O C Marcelo A D | 1993 | Journal of Bacteriology1993，175，9： | 1 |
| 5 | Body fat and insulin resist- ance independently predict increased serum C-reactive protein in hyperandrogenic women with polycystic ovary syndrome 显示文摘 | Flavia T Romolo D Roberto C | 2009 | Eur J Endocrinol2009，161，5： | 1 |
| 6 | A Global-rank-ing Local Feature Selection Method for Text Categorization显示文摘 | Roberto H W George D C Renato F C | 2012 | Expert Systems with Applications2012，39，12： | 1 |
| 7 | ESD indirect coupling modeling显示文摘 | Graziano C Roberto D L Valter M P | 1996 | IEEE Trans on EMC1996，38，3： | 1 |
| 8 | Glass fiber reinforced polymer pultruded members: constitutive model and stability analysis 显示文摘 | Antonella C Roberto D M | 2004 | Journal of Engineering Mechanics2004，130，8： | 1 |
| 9 | Robust and efficient authentication of video stream broadcasting显示文摘 | GABRIELE O STEFANO C ROBERTO D P | 2011 | ACM Transactions on Information and System Security (TISSEC)2011，14，1： | 1 |
| 10 | Implementation and testing of passive control devices based on shape memory alloy显示文摘 | Mauro D Donatello C Roberto M | 2000 | Earthquake Engineering and Structural Dynamics2000，29，2： | 1 |
| 11 | A review and a fundamental theo- ry of silicon nitride tribochemistry 显示文摘 | Roberto C D Kajdas C K | 2012 | Wear2012，288，： | 1 |
| 12 | Individual and interaction effects of vanillin and syringaldehyde on the xylitol formation by Candida guilliermondii 显示文摘 | Cortez D Y Roberto I C | 2009 | Biores Teehnol2009，101，： | 1 |
| 13 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 14 | Sequential assembly and polymerization of the polyprenol-linked pentasaccharide repeating unit of the Xanthan polysaccharide in Xanthomonas campestris显示文摘 | Luis I Roberto O C Marcelo A D | 1993 | Journal of Bacteriology1993，175，9： | 1 |
| 15 | Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD1839(Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor显示文摘 | Fortunato C Rosa C Roberto B Vincenzo D Grazia P Sabino De Placido | 2000 | Clin Cancer Res2000，6，： | 1 |
| 16 | Biochemical markers for predition of chemotherapy - induced cardiotoxicity: systemic review of the literature and recommendations for use 显示文摘 | Alberto D Roberto D Daniela C | 2008 | Am J Clin Pathol2008，130，5： | 1 |
| 17 | CTAB,Triton X-100 and freezing-tha- wing treatments of Candida guilliermondii : effects on permeability and accessibility of the glucose-6-phosphate dehydrogenase, xy- lose reductase and xylitol dehydrogenase enzymes 显示文摘 | Cortez D V Roberto I C | 2011 | New Bio- tech2011，29，2： | 1 |
| 18 | Desiccation tolerance in the moss Polytrichum formosum : Physiological and fine-structural changes during desiccation and recovery显示文摘 | Michael C F P Roberto L Jeffrey G D | 2007 | Annals of Botany2007，99，： | 1 |
| 19 | Design synthesis and biologicalac- tiveties of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors显示文摘 | Roberto D Roberta C | 2005 | J Med Chem2005，48，： | 1 |
| 20 | Glass iiber reinforced polymer pultruded members : constitutive model and stability analysis 显示文摘 | Antonella C Roberto D M | 2004 | Journal of Engineering Mechanics2004，13，8： | 1 |
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