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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | Damage identification in beam-type structures: frequency-based method vs mode-shape-based method 显示文摘 | Kim J T Ryu Y S Cho H M | 2003 | Engineering Structures2003，25，1： | 2 |
| 4 | Fabrication of homostructure ZnO p-n junctions显示文摘 | Kim W J White H M | 2000 | J Cryst Growth2000，219，： | 1 |
| 5 | 显示文摘 | Ryu S Park J H Jang H M | 2007 | Appl Phys Lett2007，91，14： | 1 |
| 6 | Transformation of isotropic fluid to nematic gel triggered by dynamic bridging of su- pramolecular nanocylinders显示文摘 | Ryu J H Lee M | 2005 | J Am Chem Soc2005，127，14： | 1 |
| 7 | Non-invasive prenatal diagnosis of fetal trisomy 21 using cell-free fetal DNA in maternal blood显示文摘 | Lim J H Park S Y Ryu H M | 2013 | Obstet Gynecol Sci2013，56，58： | 1 |
| 8 | Development of in situgelling and mucoadhesive acetaminophe liquid suppository 显示文摘 | CHOI H G JUNG J H RYU J M | 1998 | Int J Pharm1998，165，： | 1 |
| 9 | Characteristic of neuraminidase inhibitory xanthones from Cudrania tricuspidata显示文摘 | Ryu Y B Curtis-Long M J Lee J W | 2009 | Bioorg Med Chem2009，17，7： | 1 |
| 10 | Modification of rubber powder with peroxide and properties of polypropylene/rubber composites 显示文摘 | Shanmugharaj A M Kim J K Ryu S H | 2007 | Journal of Applied Polymer Science2007，104，4： | 1 |
| 11 | Ethanol fermentation from Jerusalem artichoke powder using Saccharomyces cerevisiae KCCM50549 without pretreatment for inulin hydrolysis 显示文摘 | Lim S H Ryu J M Lee H | 2011 | Bioresource Technology2011，102，2： | 1 |
| 12 | Plant growth-promoting rhizobacteria systemically protect Ara- bidopsis thaliana against cucumber mosaic virus by a salicylic acid and NPRl-independent and jasmonic acid- dependent signaling pathway 显示文摘 | RYU C M MUROHY J F MYSORE K S | 2004 | The Plant Journal2004，39，3： | 1 |
| 13 | Preparation of copolymer particles by emulsion polymerization using a polymerizable amphiphilic 显示文摘 | Hong C K Hwang M J Ryu D W | 2008 | Colloids and Surface A Physicochemical and Engineering Aspects2008，331，3： | 1 |
| 14 | Thermochemical performance of magnesium hydroxide-expanded graphite pellets for chemical heat pump显示文摘 | Zamengo M Ryu J Kato Y | 2014 | Applied Thermal Engineering2014，64，12： | 1 |
| 15 | Induced systemic resistance and promotion of plant growth by Bacillus spp 显示文摘 | KLOEPPER J W RYU C M ZHANG S | 2004 | Phytopathology2004，94，11： | 1 |
| 16 | Position-based routing algorithm for improving reliability of inter-vehicle communication显示文摘 | Ryu M Cha S Koh J | 2011 | KSII Transactions on Internet and Information Systems2011，5，8： | 1 |
| 17 | Improvement of silicon powder negative electrodes by copper electroless deposition for lithium secondary batteries显示文摘 | KIM J W RYU J H LEE K T OH S M | 2005 | J Power Sources2005，147，： | 1 |
| 18 | Plant Inversion Control of Tail-Controlled Missiles显示文摘 | Park C S Tank M J | 1997 | AIAA-97-37661997，，： | 1 |
| 19 | Infrared (IR) investigation of the structural changes of silica glasses with fictive temperature显示文摘 | Tomozawa M Hong J W Ryu S R | 2005 | J Non-Cryst Solids2005，351，： | 1 |
| 20 | Damage identification in beam-type structures:Frequency-based method vs mode- shape-based method 显示文摘 | Kim J T Ryu Y S Cho H M | 2003 | Eng Struct2003，25，1： | 1 |
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